Int J Stomatol ›› 2021, Vol. 48 ›› Issue (5): 609-613.doi: 10.7518/gjkq.2021087

• Reviews • Previous Articles     Next Articles

Smoking affects the oral microenvironment and its role in the progression of dental caries

Fan Yu(),Cheng Lei()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-12-24 Revised:2021-05-22 Online:2021-09-01 Published:2021-09-10
  • Contact: Lei Cheng;
  • Supported by:
    National Natural Science Foundation of China(81870759)


Numerous epidemiological studies report a close relationship between smoking and the occurrence of dental caries. Modern caries etiology shows that changes in the oral microenvironment including saliva flow rate, buffer capacity, composition, and oral microbial composition causes acid-forming and acid-fast bacteria to dominate. Consequently, the balance of demineralization and remineralization is broken, leading to the occurrence of caries. Other caries-related factors such as socioeconomic status and oral-health awareness also affect the occurrence and development of caries. Studies show that smoking exerts direct and indirect effects on the oral microenvironment, thereby promoting the occurrence of caries. The aim of our review is to summarize the effect of smoking on dental caries from this aspect.

Key words: smoking, dental caries, saliva, oral microorganism, nicotine

CLC Number: 

  • R781.1

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