Int J Stomatol

Int J Stomatol ›› 2023, Vol. 50 ›› Issue (2): 210-216.doi: 10.7518/gjkq.2023021

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Effects of flavonoids on oral microorganisms and its mechanism

Chen Yifei1(),Zhang Binjing1,Feng Shuqi1,Xu Rui1,Yang Shuxian1,Li Yuqing2()   

  1. 1.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Di-seases & West China School of Stomatology, Sichuan University, Chengdu 610041, China
    2.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2022-05-12 Revised:2022-09-09 Online:2023-03-01 Published:2023-03-14
  • Contact: Yuqing Li E-mail:1677935971@qq.com;liyuqing@scu.edu.cn
  • Supported by:
    National Natural Science Foundation of China(32170046);International Research and Development Program of Sichuan(2022YFH0048)

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Abstract:

Flavonoids are natural organic compounds widely existed in plants. In recent years, there has been an increasing amount of research on the effects and processes of flavonoids on oral microbes such as Streptococcus mutans, Porphyromonas gingivalis, and Candida albicans, due to their strong antibacterial activity. It demonstrates that a variety of flavonoids have an inhibitory impact on oral pathogenic bacteria and may be useful in the prevention and treatment of oral illnesses and oral health care. This review summarized the effects and mechanism of flavonoids on oral microorga-nisms and evaluated the application value of flavonoids in prevention and treatment of oral diseases and oral health care.

Key words: flavonoids, oral microorganism, antimicrobial effect, oral disease prevention

CLC Number: 

  • R 780.1

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