Int J Stomatol

Inter J Stomatol ›› 2010, Vol. 37 ›› Issue (3): 302-302～305.doi: 10.3969/j.issn.1673-5749.2010.03.016

Previous Articles     Next Articles

Research progress of resin monomer toxicity mechanism

FANG Jun-yan, LING Jun-qi   

  1. Dept. of Conservative Dentistry and Endodontics, Hospital of Stomatology, Guanghu
  • Received:2009-02-24 Revised:2009-12-03 Online:2010-05-20 Published:2010-05-20
  • Contact: LING Jun-qi

RichHTML

6

PDF (PC)

1079

Abstract: Monomers was residual when composite resin polymerized incompletely. Unpolymerized monomers could penetrate into oral, dentin and periapical tissue, contributing to the cytotoxicity and mutation toxicity. In this review,
we summarize the toxicity mechanisms about interference redox equilibrium, inhibition 3-kinase/Akt signaling cascade, activation mitogen-activated protein kinase pathway, induction gene expression of inflammatory factor and inflammatory reaction, cell cycle proteins regulatory the cell cycle of the resin monomer in cell.

Key words: resin monomer, oxidative stress, reactive oxygen species, cytotoxicity, programmed cell death, glutathione

CLC Number: 

  • R

TrendMD: 
[1] Wu Sijia,Shu Chang,Wang Yang,Wang Yuan,Deng Shuli,Wang Huiming.. Effect and research progress on root canal infection management of regenerative endodontic procedure in immature permanent teeth [J]. Int J Stomatol, 2023, 50(4): 388-394.
[2] Zhang Jingyi,Li Danwei,Sun Yu,Lei Yayan,Liu Tao,Gong Yu. In vitro cytotoxicity of composite resin and compomer and effect on osteogenic differentiation of osteoblasts [J]. Int J Stomatol, 2022, 49(4): 412-419.
[3] Ding Xu,Li Xin,Li Yan,Xia Boyuan,Yu Weixian. Research progress on the relationship among oxidative stress, mitochondrial quality control, and periodontitis [J]. Int J Stomatol, 2021, 48(4): 385-390.
[4] Zhu Junjin,Wang Jian.. Advances in the loading methods of silver nanoparticles on the surface of titanium implants [J]. Int J Stomatol, 2021, 48(3): 334-340.
[5] Zhou Feng,Chen Ye,Chen Chen,Zhang Yining,Geng Ruiman,Liu Ji. Mechanism of sirtuin 1 in regulating periodontitis [J]. Int J Stomatol, 2021, 48(3): 341-346.
[6] Wu Nan,Li Bin. Inhibitory effect of pyrroloquinoline quinone on epithelial-mesenchymal transition in tongue squamous cell carcinoma cells [J]. Int J Stomatol, 2020, 47(4): 406-412.
[7] Zhuo Yang,Shengdan Zhang,Chengcheng Liu,Yi Ding. Research progress on salivary markers for diagnosis of aggressive periodontitis [J]. Inter J Stomatol, 2019, 46(1): 55-61.
[8] Donglei Wu,Jing Liu. Research progress on the association between oxidative stress injury and certain oral diseases [J]. Inter J Stomatol, 2019, 46(1): 62-67.
[9] Chen Xiuchun, Zhang Zhimin, Hong Lihua, Zhang Yaqi, Zheng Peng, Li Wenyue. Cytotoxic mechanism of triethylene glycol dimethacrylate [J]. Inter J Stomatol, 2018, 45(2): 209-213.
[10] Zhang Peng, Ding Yi, Wang Qi. Research on the role of inflammaging in diabetes mellitus-associated periodontitis [J]. Inter J Stomatol, 2017, 44(6): 664-668.
[11] Yu Wenwen, Wang Xu, Sun Xinhua. Research progress on biological safety of orthodontic metallic appliance [J]. Inter J Stomatol, 2015, 42(5): 592-596.
[12] Wu Yuhong, Lin Juhong, Zhang Hongmei. Physicochemical and biological properties of Portland cement and mineral trioxide aggregate and their applications [J]. Inter J Stomatol, 2014, 41(6): 699-702.
[13] Liu Junchao, Pan Yaping. Cyclin-dependent kinase inhibitor protein and kinase inhibitor protein and oral diseases [J]. Inter J Stomatol, 2014, 41(6): 712-715.
[14] Huang Long, Jian Xinchun.. Areca nut-related carcinogens and oral cancer [J]. Inter J Stomatol, 2014, 41(1): 102-107.
[15] Yan Wen, Li Wei.. Cytotoxicity and genotoxicity of dental filling materials utilized in endodontic thera [J]. Inter J Stomatol, 2013, 40(5): 608-611.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[9] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[10] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .