国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (3): 335-339.doi: 10.7518/gjkq.2018.03.017
李一涵, 潘兰兰
Li Yihan, Pan Lanlan
摘要: 近年来,阿尔兹海默症(AD)患者人数随年龄呈指数式递增,且引发AD的病因至今不明确。多数研究曾表明,AD的发生与年龄老化、遗传因素、炎症反应、氧化应激等多种因素相关。最新研究证实牙周病已是引发多种系统性疾病高危险因素之一,同时有越来越多证据证实牙周病与AD发病存在密切的相关性。牙周病通过产生炎性因子和免疫反应的机制引发AD。本文就牙周病与AD发生相关性及其机制的研究作一综述。
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