国际口腔医学杂志 ›› 2019, Vol. 46 ›› Issue (6): 670-674.doi: 10.7518/gjkq.2019076

• 综述 • 上一篇    下一篇



  1. 1. 中国医科大学口腔医院牙周科 沈阳 110002
    2. 中国医科大学口腔医院综合急诊黏膜病科 沈阳 110002
  • 收稿日期:2019-01-21 修回日期:2019-05-21 出版日期:2019-11-01 发布日期:2019-11-14
  • 通讯作者: 潘亚萍 E-mail:yppan@cmu.edu.cn
  • 作者简介:张智颖,硕士,Email: 372771916@qq.com
  • 基金资助:

Research progress on Porphyromonas gingivalis outer membrane vesicles

Zhang Zhiying1,Liu Dongjuan2,Pan Yaping1()   

  1. 1. Dept. of Peridontology, Hospital of Stomatology, China Medical University, Shenyang 110002, China
    2. Dept. of Emergency and Oral Medicine, Hospital of Stomatology, China Medical University, Shenyang 110002, China
  • Received:2019-01-21 Revised:2019-05-21 Online:2019-11-01 Published:2019-11-14
  • Contact: Yaping Pan E-mail:yppan@cmu.edu.cn
  • Supported by:
    This study was supported by National Natural Science Foundation of China(81670997);Postdoctoral Funds in China(2018M640269)



关键词: 牙周炎, 牙龈卟啉单胞菌, 外膜囊泡


Porphyromonas gingivalis is one of the major periodontal pathogens. Studies have shown that outer membrane vesicle (OMV) can exchange information with host cells and other microorganisms and transmit virulence factors to cause changes in host cells. Virulence factors contained in OMV mainly include adhesins and proteolytic enzymes, which play important roles in the pathogenesis of Porphyromonas gingivalis infection. This paper reviews the occurrence of Porphyromonas gingivalis OMV and its role in the pathogenesis of Porphyromonas gingivalis infection, thereby providing a reference for the in-depth study ofPorphyromonas gingivalis OMV.

Key words: periodontitis, Porphyromonas gingivalis, outer membrane vesicle


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