国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (3): 280-285.doi: 10.7518/gjkq.2018.03.007

• 干细胞专栏 • 上一篇    下一篇

牙源性干细胞的特点及其在骨组织工程中的应用

周洁, 王颖, 张雷, 吴婷婷, 周咏, 邹多宏   

  1. 安徽医科大学口腔医学院 安徽医科大学附属口腔医院种植科 安徽省口腔疾病研究省级重点实验室 合肥 230032
  • 收稿日期:2017-11-14 修回日期:2018-01-29 发布日期:2018-05-08
  • 通讯作者: 邹多宏,副教授,博士,Email:zouduohongyy@163.com
  • 作者简介:周洁,硕士,Email:15856950201@163.com
  • 基金资助:
    国家自然科学基金(31370983);安徽省杰出青年基金(1508085J08);高校优秀青年人才支持计划重点项目(gxyqZD2016- 058)

Characteristics of dental tissue-derived stem cells and their application in bone tissue engineering

Zhou Jie, Wang Ying, Zhang Lei, Wu Tingting, Zhou Yong, Zou Duohong   

  1. College of Stomatology, Anhui Medical University, Dept. of Implantology, Affiliated Stomatological Hospital, Anhui Medical University, Key Laboratory of Oral Diseases Research in Anhui Province, Hefei 230032, China
  • Received:2017-11-14 Revised:2018-01-29 Published:2018-05-08
  • Supported by:
    This study was supported by National Natural Science Foundation of China (31370983), Excellent Youth Foundation of Anhui Scientific Committee (1508085J08) and Key Program in the Youth Elite Support Plan in Universities of Anhui Province (gxyqZD2016058).

摘要: 近年来,口腔特有的成体干细胞,包括牙髓干细胞、脱落乳牙干细胞、根尖乳头干细胞、牙周膜干细胞、牙囊前体干细胞等作为种子细胞为组织再生研究提供重要的细胞来源。现就这些牙源性干细胞的特点以及其在骨组织工程中的应用研究进行综述。

关键词: 成体干细胞, 种子细胞, 牙源性干细胞, 骨组织工程

Abstract: In recent years, adult stem cells obtained from dental tissue, including dental pulp stem cells, stem cells from human exfoliated deciduous teeth, apical papilla stem cells, periodontal ligament stem cells and follicle progenitor cells, provide sources of seed cells for oral tissue engineering in dentistry. In this paper, we review the characteristics of these adult stem cells and their applications in bone tissue engineering.

Key words: adult stem cell, seed cell, dental tissue-derived stem cell, bone tissue engineering

中图分类号: 

  • Q813.1
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