国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (2): 224-227.doi: 10.7518/gjkq.2018.02.018
郑直, 颜世果
Zheng Zhi, Yan Shiguo
摘要: 疱疹病毒是自然界中常见的病毒,与牙周炎之间关系的研究备受关注,其普遍存在于慢性牙周炎、侵袭性牙周炎患者的口腔之中,这类病毒通过对细胞的直接损伤作用,干扰宿主的免疫反应以及与牙周致病菌之间建立协同关系,在牙周炎的致病中扮演一定角色。因此,本文将疱疹病毒与牙周炎的研究现状进行综述。
中图分类号:
[1] Bilder L, Elimelech R, Szwarcwort-Cohen M, et al.The prevalence of human herpes viruses in the saliva of chronic periodontitis patients compared to oral health providers and healthy controls[J]. Arch Virol, 2013, 158(6):1221-1226. [2] Chalabi M, Rezaie F, Moghim S, et al.Periodontopa-thic bacteria and herpesviruses in chronic periodontitis[J]. Mol Oral Microbiol, 2010, 25(3):236-240. [3] Sahin S, Saygun I, Kubar A, et al.Periodontitis lesions are the main source of salivary cytomegalo-virus[J]. Oral Microbiol Immunol, 2009, 24(4):340-342. [4] Muzammil, Jayanthi D, Faizuddin M, et al. Associa-tion of interferon lambda-1 with herpes simplex vi-ruses-1 and -2, Epstein-Barr virus, and human cyto-megalovirus in chronic periodontitis[J]. J Investig Clin Dent, 2017, 8(2). doi: 10.1111/jicd.12200. [5] Sharma R, Padmalatha O, Kaarthikeyan G, et al.Comparative analysis of presence of Cytomegalo-virus (CMV) and Epsteinbarr virus -1 (EBV-1) in cases of chronic periodontitis and aggressive perio-dontitis with controls[J]. Indian J Dent Res, 2012, 23(4):454-458. [6] Kubar A, Saygun I, Ozdemir A, et al.Real-time polymerase chain reaction quantification of human cytomegalovirus and Epstein-Barr virus in periodon-tal pockets and the adjacent gingiva of periodontitis lesions[J]. J Periodontal Res, 2005, 40(2):97-104. [7] Ling PD, Lednicky JA, Keitel WA, et al.The dynamics of herpesvirus and polyomavirus reactivation and shedding in healthy adults: a 14-month longitudinal study[J]. J Infect Dis, 2003, 187(10):1571-1580. [8] Dawson DR, Wang C, Danaher RJ, et al.Real-time polymerase chain reaction to determine the prevalence and copy number of epstein-barr virus and cytome-galovirus DNA in subgingival plaque at individual healthy and periodontal disease sites[J]. J Perio-dontol, 2009, 80(7):1133-1140. [9] Kato A, Imai K, Ochiai K, et al.Higher prevalence of Epstein-Barr virus DNA in deeper periodontal pockets of chronic periodontitis in Japanese patients[J]. PLoS One, 2013, 8(8):e71990. [10] Bertoldi C, Pellacani C, Lalla M, et al.Herpes Sim-plex Ⅰ virus impairs regenerative outcomes of perio-dontal regenerative therapy in intrabony defects: a pilot study[J]. J Clin Periodontol, 2012, 39(4):385-392. [11] Petrović SM, Zelić K, Milasin J, et al.Detection of herpes simplex virus type 1 in gingival crevicular fluid of gingival sulcus/periodontal pocket using polymerase chain reaction[J]. Srp Arh Celok Lek, 2014, 142(5/6):296-300. [12] Yapar M, Saygun I, Ozdemir A, et al.Prevalence of human herpesviruses in patients with aggressive periodontitis[J]. J Periodontol, 2003, 74(11):1634-1640. [13] Saygun I, Kubar A, Ozdemir A, et al.Herpesviral-bacterial interrelationships in aggressive periodonti-tis[J]. J Periodontal Res, 2004, 39(4):207-212. [14] Ling LJ, Ho CC, Wu CY, et al.Association between human herpesviruses and the severity of periodontitis[J]. J Periodontol, 2004, 75(11):1479-1485. [15] Bilichodmath S, Mangalekar SB, Sharma DC, et al.Herpesviruses in chronic and aggressive periodontitis patients in an Indian population[J]. J Oral Sci, 2009, 51(1):79-86. [16] Rodrigues PM, Teixeira AL, Kustner EC, et al.Are herpes virus associated to aggressive periodontitis? A review of literature[J]. J Oral Maxillofac Pathol, 2015, 19(3):348-355. [17] Sharma S, Tapashetti RP, Patil SR, et al.Revelation of viral-bacterial interrelationship in aggressive perio-dontitis via polymerase chain reaction: a microbiolo-gical study[J]. J Int Oral Health, 2015, 7(9):101-107. [18] Slots J.Herpesviral-bacterial interactions in perio-dontal diseases[J]. Periodontol 2000, 2010, 52(1): 117-140. [19] Betts K, Abusleme L, Freeman AF, et al.A 17-year old patient with DOCK8 deficiency, severe oral HSV-1 and aggressive periodontitis-a case of virally induced periodontitis[J]. J Clin Virol, 2015, 63:46-50. [20] Verdugo F, Castillo A, Castillo F, et al.Epstein-Barr virus associated peri-implantitis: a split-mouth study[J]. Clin Oral Investig, 2015, 19(2):535-543. [21] Contreras A, Zadeh HH, Nowzari H, et al.Herpe-svirus infection of inflammatory cells in human pe-riodontitis[J]. Oral Microbiol Immunol, 1999, 14(4): 206-212. [22] Savard M, Gosselin J.Epstein-Barr virus immunos-suppression of innate immunity mediated by phagocytes[J]. Virus Res, 2006, 119(2):134-145. [23] Ressing ME, Horst D, Griffin BD, et al.Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products[J]. Semin Cancer Biol, 2008, 18(6):397-408. [24] Slots J, Saygun I, Sabeti M, et al.Epstein-Barr virus in oral diseases[J]. J Periodontal Res, 2006, 41(4): 235-244. [25] Lin YL, Li M.Human cytomegalovirus and Epstein-Barr virus inhibit oral bacteria-induced macrophage activation and phagocytosis[J]. Oral Microbiol Im-munol, 2009, 24(3):243-248. [26] Baqui AA, Jabra-Rizk MA, Kelley JI, et al.Enhanced interleukin-1beta, interleukin-6 and tumor necrosis factor-alpha production by LPS stimulated human monocytes isolated from HIV+ patients[J]. Immuno-pharmacol Immunotoxicol, 2000, 22(3):401-421. [27] Slots J.Herpesviruses in periodontal diseases[J]. Periodontol 2000, 2005, 38:33-62. [28] Verdugo F, Castillo A, Simonian K, et al.Periodonto-pathogen and Epstein-Barr virus contamination affects transplanted bone volume in sinus augmentation[J]. J Periodontol, 2012, 83(2):162-173. [29] Sugano N, Ikeda K, Oshikawa M, et al.Relationship between |
[1] | 王晓宇,朱昭蓉,吴亚菲,赵蕾. 中性粒细胞细胞外陷阱网与牙周炎的相关性研究进展[J]. 国际口腔医学杂志, 2020, 47(3): 304-310. |
[2] | 陈斌,徐蓉蓉,张家鼎,闫福华. 重度牙周炎患牙的保存治疗[J]. 国际口腔医学杂志, 2020, 47(2): 125-130. |
[3] | 崔钰嘉,孙建勋,周学东. 黄连素的生物学功能及治疗口腔疾病研究的进展[J]. 国际口腔医学杂志, 2020, 47(1): 115-120. |
[4] | 周婕妤,刘琳,吴亚菲,赵蕾. 微小RNA介导的牙周炎与动脉粥样硬化相关机制的研究进展[J]. 国际口腔医学杂志, 2020, 47(1): 76-83. |
[5] | 张智颖,刘东娟,潘亚萍. 牙龈卟啉单胞菌外膜囊泡的研究进展[J]. 国际口腔医学杂志, 2019, 46(6): 670-674. |
[6] | 姜亦洋,刘怡. 甲基化对牙周炎发生与发展的影响及临床应用[J]. 国际口腔医学杂志, 2019, 46(5): 593-603. |
[7] | 张佳喻,罗宁,苗棣,应绚,陈悦. 意向性牙再植治疗重度牙周炎患牙的临床研究[J]. 国际口腔医学杂志, 2019, 46(4): 400-406. |
[8] | 原振英,管翠强,南欣荣. DNA甲基化与口腔疾病的研究进展[J]. 国际口腔医学杂志, 2019, 46(4): 437-441. |
[9] | 郭淑娟, 刘倩, 丁一. 牙周病和植体周病国际新分类简介[J]. 国际口腔医学杂志, 2019, 46(2): 125-134. |
[10] | 吕慧欣,杜留熠,王鹞,于维先,任静宜,顾芯铭,周延民. 炎症小体在牙周炎中的研究进展[J]. 国际口腔医学杂志, 2019, 46(2): 186-190. |
[11] | 聂然,郭天奇,李雪,裴婷婷,秦勤,周延民. 与牙周炎相关的组织蛋白酶研究进展[J]. 国际口腔医学杂志, 2019, 46(2): 197-202. |
[12] | 王鹞,吕慧欣,杜留熠,顾芯铭,任静宜,于维先,周延民. 软脑膜在外周炎症影响神经炎症过程中的作用[J]. 国际口腔医学杂志, 2019, 46(2): 223-227. |
[13] | 杨卓,张盛丹,刘程程,丁一. 侵袭性牙周炎唾液诊断标记物的研究进展[J]. 国际口腔医学杂志, 2019, 46(1): 55-61. |
[14] | 许彩薇,薛毅,吴仲寅. 骨硬化蛋白与牙周炎相关性的研究进展[J]. 国际口腔医学杂志, 2018, 45(6): 703-709. |
[15] | 田江雪,莫龙义,贾小玥,刘程程,徐欣. 转化生长因子β在牙周炎发生发展中的作用及其机制[J]. 国际口腔医学杂志, 2018, 45(5): 553-559. |
|