Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (2): 226-229.doi: 10.3969/j.issn.1673-5749.2012.02.026

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Influence of the caseinolytic protease on the ability of Streptococcus mutans to cause dental caries

Wang Tuo, Yu Danni.   

  1. Dept. of Stomatology, The Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China
  • Received:2011-05-21 Revised:2011-12-21 Online:2012-03-01 Published:2012-03-01

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Abstract:

Streptococcus mutans is known as a primary pathogen of dental caries, it not only has an advantage over amount, but also has a strong ability to produce and resist acid. However, forming biofilms to adhere to the surface of the teeth is the most important step. The caseinolytic protease is a kind of heat shock protein, which mediates the proteolysis. This protease can remove the denatured proteins in the bacterial and play a particular role in biofilm formation and stress response reaction of the bacterial.

Key words: Streptococcus mutans, caseinolytic protease, stress response, biofilm


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