Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (1): 105-109.doi: 10.3969/j.issn.1673-5749.2012.01.029

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Relation of monocyte chemoattractant protein-1 and intercellular adhesion molecule-1 between atherosclerosis and periodontal disease

Jiao Lining, Bi Liangjia, Lin Jiang.   

  1. Dept. of Stomatology, The Affiliated Fourth Hospital of Stomatology, Harbin Medical University, Harbin 150001, China
  • Received:2010-08-07 Revised:2011-07-18 Online:2012-01-01 Published:2012-01-01

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Abstract:

Coronary heart disease on the pathologic foundation of atherosclerosis is one of the fatal diseases now, however, there is an association exists between periodontitis and atherosclerosis. Both monocyte chemoattractant protein（MCP）-1 and intercellular adhesion molecule（ICAM）-1 play important roles in the occurrence and development of atherosclerosis and periodontitis. In this article the relationship between atherosclerosis and periodontitis by means of MCP-1 and ICAM-1 is reviewed.

Key words: monocyte chemoattractant protein -1, intercellular adhesion molecule -1, periodontal disease, atherosclerosis, Porphyromonas gingivalis


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