Int J Stomatol

Int J Stomatol ›› 2026, Vol. 53 ›› Issue (1): 43-50.doi: 10.7518/gjkq.2026201

• Stem Cell • Previous Articles     Next Articles

Osteogenic effect and factors that influence dental pulp stem cells in alveolar bone regeneration

Chengxing Ding1(),Xiaolan Li2,Mingli Yang1()   

  1. 1.School of Preclinical Medicine, Zunyi Medical University, Zunyi 563000, China
    2.School of Stomatology, Zunyi Medical University, Zunyi 563000, China
  • Received:2024-12-04 Revised:2025-05-23 Online:2026-01-01 Published:2025-12-31
  • Contact: Mingli Yang E-mail:2816105292@qq.com;63677179@qq.com
  • Supported by:
    2023 Science and Technology Fund Project of Guizhou Provincial Health Commission(gzwkj2023-520);Project of Zunyi Science and Technology Department (Zunyi Science and Technology Cooperation Project HZ [2020]36);Project of Guizhou Province Science and Technology Department (Guizhou Science and Technology Coo-peration [2018]5772-043)

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Abstract:

Dental pulp stem cells (DPSCs) have potential for self-renewal and differentiation into various cell types. They can be transplanted into the defect area of the alveolar bone to induce their differentiation into osteoblasts, thereby promoting the regeneration and reconstruction of the alveolar bone. This study reviews the osteogenic ability of DPSCs in alveolar bone regeneration and the factors that influence their osteogenic ability. The challenges faced in the clinical application of DPSCs are analyzed to provide insights into the basic research and clinical application of DPSCs for repairing the alveolar bone.

Key words: dental pulp stem cell, alveolar bone, bone defect, bone regeneration

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  • R78

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Fig 1

Mechanisms and the relevant influencing factors of DPSCs in osteogenic differentiation"

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