Int J Stomatol

Inter J Stomatol ›› 2019, Vol. 46 ›› Issue (1): 43-47.doi: 10.7518/gjkq.2019.01.008

• Reviews • Previous Articles     Next Articles

Research progress on submandibular gland branching-morphogenesis and its influencing factors in embryonic mice

Zhikai Liu,Chunyi Wang,Chunjie Li()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Head and Neck Tumor Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-04-15 Revised:2018-08-02 Online:2019-01-01 Published:2019-01-11
  • Contact: Chunjie Li E-mail:lichunjie@scu.edu.cn
  • Supported by:
    This study was supported by National Natural Science Foundation of China(81500807)

RichHTML

21

PDF (PC)

495

Abstract:

As an important part of salivary glands, submandibular gland’s significance of clinical experiments and organ reconstruction is drawing more attention in recent years. In this paper, starting from the research status at abroad, we point out the submandibular gland and its basic concepts of branching morphogenesis. Then we introduce the relevant factors of affecting research in recent years such as the growth factors, hormone and micro RNA, etc..

Key words: submandibular gland, branching-morphogenesis, epidermal growth factor, fibroblast growth factor, microRNA

CLC Number: 

  • R782

TrendMD: 
[1] Sakai T . Development and regeneration of salivary gland toward for clinical application[J]. Oral Sci Int, 2016,13(1):7-14.
doi: 10.1016/S1348-8643(15)00040-3
[2] Tucker AS . Salivary gland development[J]. Semin Cell Dev Biol, 2007,18(2):237-244.
doi: 10.1016/j.semcdb.2007.01.006
[3] Koyama N, Hayashi T, Kashimata M . Regulation of branching morphogenesis in fetal mouse submandi-bular gland by signaling pathways activated by growth factors and α6 integrin[J]. J Oral Biosci, 2011,53(4):298-303.
doi: 10.1016/S1349-0079(11)80022-8
[4] Häärä O, Koivisto T, Miettinen PJ . EGF-receptor re-gulates salivary gland branching morphogenesis by supporting proliferation and maturation of epithelial cells and survival of mesenchymal cells[J]. Differen-tiation, 2009,77(3):298-306.
doi: 10.1016/j.diff.2008.10.006 pmid: 19272528
[5] Kobayashi F, Matsuzaka K, Inoue T . The effect of basic fibroblast growth factor on regeneration in a surgical wound model of rat submandibular glands[J]. Int J Oral Sci, 2016,8(1):16-23.
doi: 10.1038/ijos.2015.36 pmid: 4822181
[6] Cortez VS, Cervantes-Barragan L, Robinette ML , et al. Transforming growth factor-β signaling guides the differentiation of innate lymphoid cells in salivary glands[J]. Immunity, 2016,44(5):1127-1139.
doi: 10.1016/j.immuni.2016.03.007 pmid: 27156386
[7] Gao P, Qiao XH, Gou LM , et al. TGF-β1 attenuated branching morphogenesis of embryonic murine submandibular gland through Smad3 activation[J]. Anat Histol Embryol, 2017,46(6):600-605.
doi: 10.1111/ahe.12295 pmid: 28884513
[8] Sathi GA, Farahat M, Hara ES , et al. MCSF orches-trates branching morphogenesis in developing sub-mandibular gland tissue[J]. J Cell Sci, 2017,130(9):1559-1569.
doi: 10.1242/jcs.196907 pmid: 28348107
[9] Ingham PW, McMahon AP . Hedgehog signaling in animal development: paradigms and principles[J]. Genes Dev, 2001,15(23):3059-3087.
doi: 10.1101/gad.938601 pmid: 11731473
[10] Mizukoshi K, Koyama N, Hayashi T , et al. Shh/Ptch and EGF/ErbB cooperatively regulate branching morphogenesis of fetal mouse submandibular glands[J]. Dev Biol, 2016,412(2):278-287.
doi: 10.1016/j.ydbio.2016.02.018 pmid: 26930157
[11] Obana-Koshino A, Ono H, Miura J , et al. Melatonin inhibits embryonic salivary gland branching morpho-genesis by regulating both epithelial cell adhesion and morphology[J]. PLoS One, 2015,10(4):e0119960.
doi: 10.1371/journal.pone.0119960 pmid: 25876057
[12] Jevnaker AM, Osmundsen H . MicroRNA expression profiling of the developing murine molar tooth germ and the developing murine submandibular salivary gland[J]. Arch Oral Biol, 2008,53(7):629-645.
doi: 10.1016/j.archoralbio.2008.01.014 pmid: 18346711
[13] Gluck C, Min S, Oyelakin A , et al. RNA-seq based transcriptomic map reveals new insights into mouse salivary gland development and maturation[J]. BMC Genomics, 2016,17(1):923.
doi: 10.1186/s12864-016-3228-7 pmid: 27852218
[14] Rebustini IT, Hayashi T, Reynolds AD , et al. miR-200c regulates FGFR-dependent epithelial prolife-ration via Vldlr during submandibular gland bran-ching morphogenesis[J]. Development, 2012,139(1):191-202.
doi: 10.1242/dev.070151 pmid: 22115756
[15] Hayashi T, Koyama N, Gresik EW , et al. Detection of EGF-dependent microRNAs of the fetal mouse submandibular gland at embryonic day 13[J]. J Med Invest, 2009,56(Suppl):250-252.
doi: 10.2152/jmi.56.250 pmid: 20224191
[16] Hayashi T, Koyama N, Azuma Y , et al. Mesenchymal miR-21 regulates branching morphogenesis in murine submandibular gland in vitro[J]. Dev Biol, 2011,352(2):299-307.
doi: 10.1016/j.ydbio.2011.01.030 pmid: 21295561
[17] Wong DT . Salivary extracellular noncoding RNA: emerging biomarkers for molecular diagnostics[J]. Clin Ther, 2015,37(3):540-551.
doi: 10.1016/j.clinthera.2015.02.017 pmid: 25795433
[18] Shi H, Cao N, Pu Y , et al. Long non-coding RNA expression profile in minor salivary gland of primary Sjögren’s syndrome[J]. Arthritis Res Ther, 2016,18(1):109.
doi: 10.1186/s13075-016-1005-2 pmid: 4869341
[19] Kwon HR, Larsen M . The contribution of specific cell subpopulations to submandibular salivary gland branching morphogenesis[J]. Curr Opin Genet Dev, 2015,32:47-54.
doi: 10.1016/j.gde.2015.01.007 pmid: 25706196
[20] Rugel-Stahl A, Elliott ME, Ovitt CE . Ascl3 marks adult progenitor cells of the mouse salivary gland[J]. Stem Cell Res, 2012,8(3):379-387.
doi: 10.1016/j.scr.2012.01.002 pmid: 22370009
[21] Nelson DA, Manhardt C, Kamath V , et al. Quan-titative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation[J]. Biol Open, 2013,2(5):439-447.
doi: 10.1242/bio.20134309 pmid: 3654261
[22] Lombaert IM, Abrams SR, Li L , et al. Combined KIT and FGFR2b signaling regulates epithelial progenitor expansion during organogenesis[J]. Stem Cell Reports, 2013,1(6):604-619.
doi: 10.1016/j.stemcr.2013.10.013 pmid: 24371813
[23] Ray S, Yuan D, Dhulekar N , et al. Cell-based multi-parametric model of cleft progression during sub-mandibular salivary gland branching morphogenesis[J]. PLoS Comput Biol, 2013,9(11):e1003319.
doi: 10.1371/journal.pcbi.1003319 pmid: 24277996
[24] Ogawa M, Oshima M, Imamura A , et al. Functional salivary gland regeneration by transplantation of a bioengineered organ germ[J]. Nat Commun, 2013,4:2498.
doi: 10.1038/ncomms3498 pmid: 24084982
[25] Racz GZ, Zheng C, Goldsmith CM , et al. Toward gene therapy for growth hormone deficiency via salivary gland expression of growth hormone[J]. Oral Dis, 2015,21(2):149-155.
doi: 10.1111/odi.12217 pmid: 24320050
[1] Zhou Jinkuo,Zhang Jinhong,Shi Xiaojing,Liu Guangshun,Jiang Lei,Liu Qianfeng. Influences of long noncoding RNA small nucleolar RNA host gene 22 on the cell proliferation, invasion and migration of oral squamous carcinoma cells by regulating microRNA-27b-3p [J]. Int J Stomatol, 2024, 51(1): 52-59.
[2] Li Liheng,Wang Rui,Wang Xiaoming,Zhang Zhiyi,Zhang Xuan,An Feng,Wang Qin,Zhang Fan. Effects of circular RNA hsa_circ_0085576 on cell migration and invasion of oral squamous cell carcinoma by regulating the microRNA-498/B-cell-specific Moloney murine leukemia virus integration site 1 axis [J]. Int J Stomatol, 2024, 51(1): 60-67.
[3] Qian Suting,Ding Lingmin,Ji Yaning,Lin Jun.. Differential expression of microRNA in gingival crevicular fluid of periodontitis and its regulatory mechanism on periodontitis [J]. Int J Stomatol, 2022, 49(3): 349-355.
[4] Ai Xiaoqing,Dou Lei,Qiao Xin,Yang Deqin. MicroRNA profile of exosomes derived from dental pulp stromal cells under three-dimensional culture condition [J]. Int J Stomatol, 2022, 49(1): 27-36.
[5] Shen Jie,He Di,Liu Yanming. Research progress on the functional surgery of benign submandibular gland tumors [J]. Int J Stomatol, 2021, 48(2): 230-237.
[6] Sun Jianwei,Lei Lihong,Tan Jingyi,Chen Lili. Regulation of osteoimmunology by MicroRNA 155 and research progress of its possible mechanism in periodontitis [J]. Int J Stomatol, 2020, 47(5): 607-615.
[7] Zhou Jieyu,Liu Lin,Wu Yafei,Zhao Lei. Research progress on microRNA-mediated mechanisms between periodontitis and atherosclerosis [J]. Int J Stomatol, 2020, 47(1): 76-83.
[8] Zhang Xiaomin,Gao Ying. Research progress on recurrent sialoliths in residual Wharton’s duct [J]. Int J Stomatol, 2019, 46(5): 604-608.
[9] Dingli Feng,Lidan Zhuo,Di Lu,Hongyan Guo. Mechanism of microRNA modulation of cartilage differentiation in mesenchymal stem cells [J]. Inter J Stomatol, 2018, 45(6): 640-645.
[10] Chuan Fang,Yadong Li. Investigative progresses of microRNA in oral squamous cell carcinoma [J]. Inter J Stomatol, 2018, 45(6): 646-651.
[11] Hao Yilin, Fang Fuchun, Wu Buling. Functions of microRNA on the osteogenic differentiation of human periodontal ligament-derived cells [J]. Inter J Stomatol, 2018, 45(1): 46-49.
[12] Liu Runheng, Liu Yudong, Chen Zhuofan.. Role and mechanism of microRNA in osteogenic differentiation [J]. Inter J Stomatol, 2017, 44(1): 108-113.
[13] Geng Fengxue, Pan Yaping.. Biological functions of microRNA-203 and its role in oral diseases [J]. Inter J Stomatol, 2016, 43(6): 685-689.
[14] Li Long, Huang Hongzhang.. Role of microRNA-205 on chemoresistance and its mechanism in tumor [J]. Inter J Stomatol, 2016, 43(6): 734-738.
[15] Li Hongyu, Huang Hongzhang. Mechanisms of the transcript factor Snail during palatogenesis [J]. Inter J Stomatol, 2016, 43(4): 468-472.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[9] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[10] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .