Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (4): 420-424.doi: 10.7518/gjkq.2018.04.009

• Reviews • Previous Articles     Next Articles

Research progress on non-coding RNAs in tongue squamous cell carcinoma

Wang Liping, Zha Jun, Ge Linhu.   

  1. Dept. of Implantology, Stomatology Hospital of Guangzhou Medical University, Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Guangzhou 510140, China
  • Received:2017-11-01 Revised:2018-02-20 Online:2018-07-02 Published:2018-07-02
  • Supported by:
    This study was supported by Guangdong Provincial Science and Technology Agency (2013B021800186).

Abstract: As the development of genomics and transcriptomics, non-coding RNAs (ncRNAs) have been paid much attention. Previous studies have suggested that ncRNAs could regulate gene expression through several biological processes such as chromosome remodeling, transcription, and posttranscription translation. Abnormal versions of ncRNAs are closely related to several human diseases such as the generation and development of tumors. Therefore, ncRNAs may become novel biomarkers in the diagnosis, prognosis and target therapies of tumor research. As the essential role of ncRNAs playing in tongue squamous cell carcinoma (TSCC), the latest domestic and foreign literatures in TSCC progression were reviewed in this article.

Key words: non-coding RNA, tongue squamous cell carcinoma, biomarker, target therapy

CLC Number: 

  • Q52

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