Int J Stomatol

Inter J Stomatol ›› 2014, Vol. 41 ›› Issue (3): 347-350.doi: 10.7518/gjkq.2014.03.023

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Calcium and phosphorus remineralization and its system

Xu Pengcheng, Xu Xin, Zhou Xuedong   

  1. State Key Laboratory of Oral Diseases, Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2013-04-09 Revised:2013-12-20 Online:2014-05-01 Published:2014-05-01

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Abstract:

Dental caries is a highly prevalent disease that progresses from initial demineralization to eventual cavitation on the dental hard tissue. Calcium and phosphate ions are the material basis of remineralization. Enamel remineralization easily occurs when calcium and phosphate ions increase. Amorphous calcium phosphate(ACP) can be combined with fluoride to produce calcium phosphate fluoride(ACPF). ACP and ACPF can provide available calcium phosphate and fluoride ions to the oral environment to promote enamel remineralization. However, the ability of ACP and ACPF to promote remineralization is reduced because of the rapid deposition. Casein phosphopeptide-amorphous calcium phosphate complexes(CPP-ACP) conserve calcium. Phosphate ions can provide a continuous supply of calcium phosphate to the oral environment. CPP-ACP can be combined with fluoride to produce CPP-ACPF, which can constantly release calcium, phosphate, and fluoride ions to promote enamel remineralization.

Key words: dental caries, remineralization, fluoride, amorphous calcium phosphate, casein phosphopeptide

CLC Number: 

  • R 781.1

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[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
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[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .