Int J Stomatol

Inter J Stomatol ›› 2010, Vol. 37 ›› Issue (5): 597-599.doi: 10.3969/j.issn.1673-5749.2010.05.029

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Growth factors in vascularization of adipose tissue engineering

KONG Zi-ren, YANG Xiao-juan, TIAN Weidong.   

  1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
  • Online:2010-09-20 Published:2010-09-20

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Abstract:

Tissue engineering is the construction of new tissue and organs for reparative purposes. In order to implant tissues of greater size to survive, the tissue has to be vascularized, and implementing the vascularization as early as possible is pivotal to the success of the engineered tissue. Adipose tissue engineers use two main methods to create a vascularised structure: Stimulation of the endogenous angiogenic responses by the vascular growth factors, and formation of structures that mimic the vascular tree of the organ or tissue to be replaced. We will illustrate the growth factors of vascularization utilized for obtaining optimal results in the field, and the fabricating methods of the scaffold using these vascular growth factors in vivo and in vitro.

Key words: vascularization, growth factor, adipose tissue engineeri


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