Int J Stomatol

Int J Stomatol ›› 2023, Vol. 50 ›› Issue (2): 177-185.doi: 10.7518/gjkq.2023005

• Original Articles • Previous Articles     Next Articles

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revascularization Meta-analysis of the efficacy comparison between endodontic1(),Zhuanzhuan apexification Li1,2()   

  1. 1.School of Stomatology, Inner Mongolia Medical University, Hohhot 010059, China
    2.Dept. of Stomatology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China
  • Received:2022-02-13 Revised:2022-07-19 Online:2023-03-01 Published:2023-03-14
  • Contact: apexification Li Zhuanzhuan E-mail:158787309@qq.com;endotana@163.com

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Abstract:

Objective To explore the efficacy of pulp revascularization and apexification in the treatment of irrever-sible pulp damage in young permanent teeth by Meta-analysis. Methods Foreign language databases (PubMed, Embase, and Cochrane library) and Chinese databases (China National Knowledge Infrastructure, SinoMed, Wanfang, and VIP) were searched from January 2001 to October 2021 for the randomized controlled trial (RCT) of two methods for the treatment of irreversible damage to young permanent dental pulp. The screening, data extraction, and quality evaluation were conducted by two members of the research team independently and in strict accordance with the inclusion and exclusion criteria. Meta-analysis was performed using RevMan 5.3 and STATA 12.0 software. Results A total of 19 RCT studies were included, and the results of the meta-analysis showed the significantly higher success rate of pulp revascularization in the treatment of irreversible damage to the pulp of young permanent teeth compared with that of apexification (P<0.05). Pulp revascularization also promoted the increase in tube wall thickness (P<0.05), root extension (P<0.05), and the incidence of complications (P<0.05). Conclusion Pulp revascularization has a higher success rate and a better efficacy in promoting root development than apexification.

Key words: Meta-analysis, young permanent teeth, irreversible damage to the dental pulp, pulp revascularization, apexification

CLC Number: 

  • R 781.34

TrendMD: 

Fig 1

Flow chart of literature screening"

Tab 1

Baseline characteristics of patients included in the study"

参考

文献

发表时

间/年

随机

方法

病例

总数

病程/d年龄/岁总有效率/%结局指标
研究组对照组研究组对照组研究组对照组

[13]

[17]

[1]

[24]

[22]

[21]

[20]

[23]

[25]

[2]

[14]

[16]

[10]

[15]

[11]

[18]

[12]

[19]

[26]

2020

2018

2021

2019

2018

2019

2019

2020

2017

2020

2018

2018

2021

2017

2020

2017

2017

2017

2017

①

①

①

①

②

②

①

②

①

①

①

①

①

①

③

④

①

②

⑤

80

136

84

74

74

80

86

76

100

78

84

78

120

67

64

96

80

78

103

28.00±0.34

—

—

—

4.90±1.70

1.70±0.30

—

8.50±2.90

8.20±1.20

8.30±1.70

9.52±1.12

—

—

9.47±0.94

—

3.52±0.66

3.62±0.65

5.51±0.74

—

27.00±0.31

—

—

—

5.40±2.10

1.50±0.20

—

8.60±2.50

8.50±1.50

8.60±1.30

9.49±1.04

—

—

8.69±0.67

—

3.65±0.85

3.56±0.74

5.47±0.72

—

12.10±1.20

10.51±1.09

10.54±0.96

13.14±1.32

13.12±1.10

12.70±0.30

12.30±3.50

13.60±2.40

12.30±2.20

11.20±1.30

11.58±2.14

11.18±2.66

9.42±1.73

12.03±2.18

7~14

9.61

9.27

9.18±2.14

6~18

12.12±1.20

10.20±1.31

10.33±0.82

13.25±1.29

12.73±2.20

12.50±3.20

11.90±3.20

12.50±2.30

11.40±2.50

11.50±1.10

11.6±2.24

11.12±2.13

9.53±1.83

12.03±2.18

7~14

9.04

9.04

9.21±2.16

6~18

80.00

77.49

78.57

83.78

81.08

62.00

81.40

73.68

—

82.05

76.19

76.92

75.00

75.76

75.00

83.00

85.00

76.92

97.00

85.00

94.12

95.24

97.30

94.59

95.00

95.35

94.74

—

97.44

92.86

94.87

90.00

94.12

93.75

97.90

97.50

94.87

89.80

①②

①②④

①②

①②

①②

①②

①②

①②④

②

①②④

①②④

①②④

①②

①②

①②③④

①②③

①②③

①②③

①②③

Tab 2

Risk bias assessment included in the literature"

参考

文献

随机

分组

分配

隐藏

盲法

数据

完整

选择

报告

其他

偏倚

[10]212222
[11]012222
[12]212222
[13]212222
[14]212222
[15]212222
[16]212222
[17]212222
[18]012222
[19]212222
[20]112222
[21]112222
[2]212222
[22]112222
[1]212222
[23]112222
[24]212222

[25]

[26]

2

2

1

1

2

2

2

2

2

2

2

2

Fig 2

Comparison of the total success rate between pulp revascularization and apical induction"

Fig 3

Comparison of the wall thickness of the two methods before treatment"

Fig 4

Comparison of wall thickness after two methods of treatment"

Fig 5

Comparison of the length of anterior teeth treated by two methods"

Fig 6

Comparison of tooth length after two treatments"

Fig 7

Comparison of the incidence of complications after two methods of treatment"

Fig 8

Funnel chart comparing the total success rate of the two methods"

Fig 9

Funnel diagram after trimming"

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