Int J Stomatol ›› 2021, Vol. 48 ›› Issue (2): 173-179.doi: 10.7518/gjkq.2021015

• Original Articles • Previous Articles     Next Articles

Meta-analysis of the long-term stability of serious anterior skeletal open-bite malocclusion after orthodontic surgery

Liu Ling(),Gong Renguo(),Dong Xiuhua,Liu Rumeng   

  1. The First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, China
  • Received:2020-08-24 Revised:2020-12-19 Online:2021-03-01 Published:2021-03-17
  • Contact: Renguo Gong;


Objective The aim of this systematic review was to analyse the long-term stability of a serious anterior skeletal open-bite malocclusion with orthodontic combined surgical treatments. Methods Data were obtained from SCI, Medline, PubMed, Cochrane Library, EMBASE, Springer, DOI and other foreign databases, such as Chinese Biomedical Literature Database, China National Knowledge Infrastructure database, VIP database for Chinese technical periodicals, the digital journal of Wan Fang Data and other Chinese databases. The literatures, which consisted of randomised controlled trials, quasi-randomised controlled trials and clinical case-control trials, were selected and evaluated independently by two investigators in accordance with the inclusion and exclusion criteria. Then, Meta-analysis was performed on the literatures that met the inclusion criteria. Results The six references (five foreign articles and one Chinese article) that met the requirements were pre-post case-control studies with a total of 220 patients. Meta-analysis showed that SNA, SNB, ANB, MP-PP, SN-PP, N-Me, ANS-Me, S-G0, OB, OJ, L1-MP/(°), L1-MP/mm, U1-PP/(°) and U1-PP/mm before operation and at least 1 year after operation had no statistical difference, whereas MP-SN had statistical difference.Conclusion Orthodontic and surgical treatment for serious anterior skeletal open-bite malocclusion could keep relative stability, except a little replace of the mandibular.

Key words: skeletal anterior open-bite, orthodontic treatment, stability, Meta-analysis

CLC Number: 

  • R783.5


Fig 1

Process of literature screening and results"

Tab 1

Characteristics of included trials"

纳入研究 研究
结局指标 结论
CCT 自身
81(22/59) 24.6 a、b、c OB 术后2年覆保持相对稳定
CCT 自身
21(10/11) 23.6 a、b、c SNA、SNB、ANB、MP-PP、SN-PP、OB、OJ、L1-MP、U1-PP 术后1年上、下颌硬组织均有轻微复发,前牙覆 稳定
CCT 自身
49(18/31) 20.9 a、b、c SNA、SN-PP、U1-PP、L1-PP、U6-PP、S-G0、N-Me、ANS-Me、N-ANS、OJ、OB 术后1年硬组织及牙齿都保持很好的稳定,但腭平面倾斜角度有复发
CCT 自身对照 58(18/40) 23 a、b、c SNA、SNB、ANB、MP-SN、MP-PP、SN-PP、L1-MP、OB、OJ 术后2年上颌硬组织保持良好的稳定,下颌有轻微复发,术后0~3周颌间固定可增强稳定性
CCT 自身对照 24(10/14) 30.8 a、b、c SNA、SNB、ANB、MP-SN、MP-PP、SN-PP、U1-PP、L1-MP、OB 术后2年上颌垂直向有轻微复发,下颌垂直向及矢状向均有轻微复发
CCT 自身对照 20(8/12) 26.5 a、b、c MP-SN、MP-PP、SN-PP、U1-PP、L1-MP、S-G0、N-Me、ANS-Me、N-ANS、OB 术后15年骨骼出现一定程度的复发,但是前牙覆基本稳定。双颌手术对矫正骨性开具有良好的临床效果

Tab 2

GRADE analysis results"

研究指标 研究数量 病例数 MD(95%CI) 证据质量 结局指标
术后 术后≥1年
SNA 4 129 129 0.63(0.43,1.68) 中等质量 关键
SNB 3 91 91 1.07(0.17,2.30) 中等质量 关键
ANB 3 91 91 0.60(1.42,0.22) 中等质量 关键
MP-SN 3 80 80 1.59(3.74,0.55) 中等质量 关键
MP-PP 4 101 101 1.05(2.81,0.71) 中等质量 关键
SN-PP 4 139 139 1.05(2.81,0.71) 中等质量 关键
N-Me 2 48 48 0.17(2.28,2.62) 中等质量 关键
ANS-ME 2 48 48 0.74(2.93,1.45) 中等质量 关键
S-G0 2 48 48 0.74(2.93,1.45) 中等质量 关键
OB 6 220 220 0.35(1.30,0.59) 中等质量 关键
OJ 3 117 117 0.28(1.25,0.69) 中等质量 关键
L1-MP/(°) 3 117 117 0.32(1.97,1.33) 中等质量 关键
L1-MP/mm 2 22 22 0.43(2.80,1.93) 中等质量 关键
U1-PP/(°) 2 59 59 1.48(5.39,2.43) 中等质量 关键
U1-P/mm 3 60 60 0.22(1.66,1.22) 中等质量 关键
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