Int J Stomatol

Inter J Stomatol ›› 2010, Vol. 37 ›› Issue (4): 447-450.doi: 10.3969/j.issn.1673-5749.2010.04.020

Previous Articles     Next Articles

Role of epigenetics in tooth morphogenesis

MA Liang, WANG Sheng-chao, ZHANG Ya-qing.   

  1. （Dept. of Conservative Dentistry and Endodontics, School of Stomatology, The Fourth Military Medical University, Xi′ an 710032, China）
  • Online:2010-07-20 Published:2010-07-20

RichHTML

9

PDF (PC)

1127

Abstract: As one of the research fronts of bioscience in the age of postgenome, epigenetic inheritance has close relationship with cell differentiation, ontogenesis and evolution, aging and the development of disease. In the previous study of developmental variations of tooth morphology, the research mainly focused on the mutation of related genes of tooth morphogenesis. But during the study on tooth phenotype of monozygotic twins, researchers found that the tooth phenotypes between monozygotic twins whose genes are identical are often different from each other. So they suggested that, environment, nutrition, living habits and many other non-genetic factors can interact with gene factor and form a mode of polygenetic inheritance which has an influence on the tooth morphogenesis of descendents. Morphological study, genetic model study and related-gene study are the mostly used research methods. In this review, the epigenetic phenomena involved in the morphogenesis of teeth and research progress were discussed.

Key words: tooth development, epigenetic inheritance, gene


TrendMD: 
[1] Chang Xinnan,Liu Lei. Applications and research progress of biodegradable magnesium-based materials in craniomaxillofacial surgery [J]. Int J Stomatol, 2024, 51(1): 107-115.
[2] Zhou Jinkuo,Zhang Jinhong,Shi Xiaojing,Liu Guangshun,Jiang Lei,Liu Qianfeng. Influences of long noncoding RNA small nucleolar RNA host gene 22 on the cell proliferation, invasion and migration of oral squamous carcinoma cells by regulating microRNA-27b-3p [J]. Int J Stomatol, 2024, 51(1): 52-59.
[3] Xia Weiyao,Jia Zhonglin. Research progress on the relationship between vitamin and oral clefts [J]. Int J Stomatol, 2023, 50(6): 632-638.
[4] Wang Luodan,Fan Hong. Morphological characteristics of sella turcica and its relationship with malocclusion [J]. Int J Stomatol, 2023, 50(6): 653-660.
[5] Hu Jia,Wang Xiuqing,Lu Guoying,Huang Xiaojing.. Regenerative endodontic procedures for permanent tooth with immature apices in adult patients [J]. Int J Stomatol, 2023, 50(6): 686-695.
[6] Gong Meiling,Cheng Xingqun,Wu Hongkun.. Research progress on the correlation between Parkinson’s disease and periodontitis [J]. Int J Stomatol, 2023, 50(5): 587-593.
[7] Wang Jiaxi,Mingyue Lü,Yuan Quan. Research progress on sticky bone in oral tissue regeneration [J]. Int J Stomatol, 2023, 50(5): 594-602.
[8] Wu Sijia,Shu Chang,Wang Yang,Wang Yuan,Deng Shuli,Wang Huiming.. Effect and research progress on root canal infection management of regenerative endodontic procedure in immature permanent teeth [J]. Int J Stomatol, 2023, 50(4): 388-394.
[9] Wang Chunyi,Li Jingtao.. A case of rare mandible and lower lip duplication and literature review [J]. Int J Stomatol, 2023, 50(4): 452-456.
[10] Fan Lin,Sun Jiang.. Application of microneedles in stomatology [J]. Int J Stomatol, 2023, 50(4): 472-478.
[11] Xia Weiyao,Luo Yankun,Jia Zhonglin. Review of the precise diagnosis and genetic etiology of Pierre Robin sequence [J]. Int J Stomatol, 2023, 50(3): 287-292.
[12] Xu Yanxue,Fu Li.. Research progress on functionally graded membranes for guided bone regeneration [J]. Int J Stomatol, 2023, 50(3): 353-358.
[13] Qiao Yuxuan,Li Ying. Research progress on the genes related of the hereditary gingival fibromatosis [J]. Int J Stomatol, 2023, 50(2): 217-223.
[14] Wang Jingyan,Qin Man,Wang Xin.. Research progress on the clinical characteristics of Axenfeld-Rieger syndrome and the pathogenic mechanisms of paired-like homeodomain transcription factor 2 mutations [J]. Int J Stomatol, 2023, 50(2): 224-229.
[15] Yang Mengyao,Gao Xianling,Deng Shuli. Application of electrospun nanofibers in periodontal regeneration [J]. Int J Stomatol, 2023, 50(1): 10-18.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .