Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (6): 665-669.doi: 10.3969/j.issn.1673-5749.2011.06.013

Previous Articles     Next Articles

Research progress on side population cells

Wang Wenjing, Wei Xi.   

  1. Dept. of Conservative Dentistry and Endodontics,Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat -Sen University, Guangzhou 510055,China
  • Received:2010-08-01 Revised:2011-06-23 Online:2011-11-20 Published:2011-11-20

RichHTML

2

PDF (PC)

1875

Abstract:

A defining property of side population cells（SP cell） is low fluorescence after staining with Hoechst33342. Adenosine triphosphate binding cassette superfamily G member-2 of transport protein（ABCG-2） is an important determinant of the SP phenotype, and have biofunctions on SP cells. SP cells have now been isolated from a wide variety of mammalian tissues, most of which, including the dental pulp SP cells, showed a stem-cell like potential of self-renewal and multilineage differentiation. Due to its unique anatomy and poor blood circulation, dental pulp is vulnerable to external stimulates, however hardly inreversible. Dental pulp SP cells as newly discovered stem-like cells may illustrate a good prospect of application and extension in dental pulp damage repair. This article intended to give an review on formation of the phenotype of SP cells, expression of stem cellrelated antigens of SP cells, stem-like cells’potential and the differences between SP and stem cells. Most of all, the statues and prospects of research on dental SP cells.

Key words: side population cell, stem cell, tissue engineering, regeneration


TrendMD: 
[1] Chang Xinnan,Liu Lei. Applications and research progress of biodegradable magnesium-based materials in craniomaxillofacial surgery [J]. Int J Stomatol, 2024, 51(1): 107-115.
[2] Chen Runzhi,Zhang Wentao,Chen Feng,Yang Fan. Modification of silk fibroin-based hydrogels and their applications for bone tissue engineering [J]. Int J Stomatol, 2023, 50(6): 739-746.
[3] Wang Jiaxi,Mingyue Lü,Yuan Quan. Research progress on sticky bone in oral tissue regeneration [J]. Int J Stomatol, 2023, 50(5): 594-602.
[4] Yu Lerong,Li Xiangwei,Ai Hong. Research progress on the stemness maintenance of dental pulp stem cells [J]. Int J Stomatol, 2023, 50(4): 463-471.
[5] Fan Lin,Sun Jiang.. Application of microneedles in stomatology [J]. Int J Stomatol, 2023, 50(4): 472-478.
[6] Wu Jiaxin,Cheng Xingqun,Wu Hongkun.. Clinical application and research progress on hyaluronic acid in the repair of papillary height loss [J]. Int J Stomatol, 2023, 50(3): 347-352.
[7] Xu Yanxue,Fu Li.. Research progress on functionally graded membranes for guided bone regeneration [J]. Int J Stomatol, 2023, 50(3): 353-358.
[8] Yang Mengyao,Gao Xianling,Deng Shuli. Application of electrospun nanofibers in periodontal regeneration [J]. Int J Stomatol, 2023, 50(1): 10-18.
[9] Li Peitong,Shi Binmian,Xu Chunmei,Xie Xudong,Wang Jun.. Distribution and role of Gli1+ mesenchymal stem cells in teeth and periodontal tissues [J]. Int J Stomatol, 2023, 50(1): 37-42.
[10] Man Yi, Huang Dingming. Combined treatment strategy of oral implantology and endodontics microsurgery: clinical protocol and practical cases (part 2) [J]. Int J Stomatol, 2022, 49(6): 621-632.
[11] Man Yi, Huang Dingming. Combined treatment strategy of oral implantology and endodontic microsurgery for bone augmentation and en-dodontic diseases in aesthetic area (part 1): application basis and indications [J]. Int J Stomatol, 2022, 49(5): 497-505.
[12] Li Pei,Lin Ling,Zhao Wei.. Research progress on the stem cells from human exfoliated deciduous teeth in the regeneration and repair of oral tissue [J]. Int J Stomatol, 2022, 49(4): 483-488.
[13] Cai Chaoying,Chen Xuepeng,Hu Ji’an. Research progress on exosome composite scaffolds in oral tissue engineering [J]. Int J Stomatol, 2022, 49(4): 489-496.
[14] Cai Yunzhu,Zhu Shu,Liu Yao,Chen Xu.. Research progress on dental stem cells in the treatment of nervous system diseases [J]. Int J Stomatol, 2022, 49(3): 255-262.
[15] Hong Yaya,Chen Xuepeng,Si Misi. Advances in research on noncoding RNA during the osteogenic differentiation of dental follicle stem cells [J]. Int J Stomatol, 2022, 49(3): 263-271.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[9] . [J]. Foreign Med Sci: Stomatol, 2004, 31(02): 126 -128 .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .