Int J Stomatol

Inter J Stomatol ›› 2017, Vol. 44 ›› Issue (2): 195-199.doi: 10.7518/gjkq.2017.02.016

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A review on the role of Veillonella in caries and its interaction with Streptococcus

Wang Yuxia, Zhou Xuedong, Li Mingyun.   

  1. State Key Laboratory of Oral Diseases, Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2016-03-20 Online:2017-03-01 Published:2017-03-01
  • Supported by:
    This study was supported by the National Natural Science Foundation of China(81400501, 81430011) and the International Science and Technology Cooperation Program of China(2014DFE30180).

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Abstract: The genus Veillonella is a member of the normal oral flora and is highly abundant in the human oral cavity. Veillonella utilizes lactate, which ameliorates the caries process. However, Resultsof in vitro studies and rat model systems are ambiguous. With the development of human oral microbiome research, several studies reported that the frequency of Veillonella in caries-activated individuals is higher than that in caries-free ones, and the distribution of Veillonella is highly related to some cariogenic Streptococcus species. Veillonella facilitates the action of some cariogenic Streptococcus species, such as Streptococcus mutans in caries development. These findings create new focus on the genus Veillonella as a factor relating to caries. This paper provides a review on the distribution of Veillonella in human oral cavity, the relationship between Veillonella and caries, and the relationship between Veillonella and Streptococcus species related to caries.

Key words: Veillonella, Streptococcus, dental caries

CLC Number: 

  • R780.2

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