Int J Stomatol

Inter J Stomatol ›› 2019, Vol. 46 ›› Issue (1): 62-67.doi: 10.7518/gjkq.2019.01.011

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Research progress on the association between oxidative stress injury and certain oral diseases

Donglei Wu,Jing Liu()   

  1. School of Stomatology, Jinan University, Guangzhou 510630, China
  • Received:2018-02-03 Revised:2018-10-12 Online:2019-01-01 Published:2019-01-11
  • Contact: Jing Liu E-mail:tjliu@jnu.edu.cn
  • Supported by:
    This study was supported by Excellent Talents Funding of Jinan University(51025036)

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Abstract:

Oxidative stress is a state in which oxidation exceeds the antioxidant systems when the endogenous antioxidant system cannot effectively remove the large amount of free radicals accumulated in the body. It participates in the development of various diseases. The oral cavity is usually attacked by multiple endogenous or exogenous stimulations, which can lead to stress injury. This article reviews the research progress of oxidative stress in oral and maxillofacial regions induced by various peripheral stimuli and its correlation with related diseases, including temporomandibular disorders, masticatory muscle diseases, periodontal diseases, oral cancer and precancerous lesions. It also provides a new idea for the etiologic investigation, diagnosis and treatment of oral diseases from the perspective of oxidative stress. Moreover, it provides an update of the literature concerning the association of oxidative stress with pathological conditions related to oral cavity, focusing on the diagnostic and therapeutic importance of the tests based on saliva specimens in a preventive perspective.

Key words: oral diseases, oxidative stress, antioxidant, reactive oxygen species

CLC Number: 

  • R781

TrendMD: 
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