关键词: 唇腭裂, 上呼吸道感染, 生命体征

Abstract: Objective This study aims to test the correlations between upper respiratory infection(URI) and vital signs after cleft lip and/or palate(CL/P) surgery to find out some preoperative manifestations that may predict surgical risk. Methods The investigators implemented retrospective studies. A total of 1 000 medical records of infants who had CL/P surgery were randomly collected. The predictor variable was several preoperative symptoms related to URI, and the outcome variable was vital signs after operation. Then, two kinds of variables were exchanged. Descriptive and univariate analyses were computed to find the links. Results About 93.3% of the infants suffered abnormal vital signs within 24 h after operation, but most complications were mild. Two groups, which were divided by whether the highest preoperative temperature was normal or not, had statistically different proportions of abnormal postoperative temperature and systolic blood pressure(SBP) (P<0.05). Univariate analysis results: an excessive white blood cell count caused statistically different postoperative SBP and respiratory rate, as compared with the normal white blood cell count(P<0.05). A fever caused different postoperative temperature, SBP, and respiratory rate(P<0.05). A diagnosis of URI caused different postoperative SBP and oxyhemoglobin saturation(P<0.05). Conclusion Tolerating CL/P surgery under general anesthesia is relatively safe for children with only slight URI symptoms, whereas a careful monitoring is indispensable. Moreover, temperature before surgery is a sensitive indicator, and white blood cell count and diagnosis of URI are also ponderable.

Key words: cleft lip and/or palate, upper respiratory infection, vital sign