国际口腔医学杂志

国际口腔医学杂志 ›› 2022, Vol. 49 ›› Issue (2): 144-152.doi: 10.7518/gjkq.2022040

• 论著 • 上一篇    下一篇

替牙期骨性Ⅲ类单侧完全性唇腭裂与非唇腭裂患者牙弓形态的对比研究

张琦1,2(),范存晖1,2(),杨茜1,2,李然3,徐晓琳4,丁玮1,2,王文惠1,2,杨彩秀1,2   

  1. 1.青岛大学附属医院口腔正畸科 青岛 266000
    2.青岛大学口腔医学院 青岛 266000
    3.济宁医学院附属医院口腔正畸科 济宁 272000
    4.烟台市口腔医院口腔正畸科 烟台 264010
  • 收稿日期:2021-07-09 修回日期:2021-11-10 出版日期:2022-03-01 发布日期:2022-03-15
  • 通讯作者: 范存晖
  • 作者简介:张琦,硕士,Email： 525145681@qq.com
  • 基金资助:
    青岛大学附属医院“临床医学+X”科研项目(2020-2021)

Dental arch morphology between patients with unilateral complete cleft lip and palate and patients with non-cleft lip and palate with a class Ⅲ skeletal relationship in mixed dentition stage: a comparative study

Zhang Qi1,2(),Fan Cunhui1,2(),Yang Qian1,2,Li Ran3,Xu Xiaolin4,Ding Wei1,2,Wang Wenhui1,2,Yang Caixiu1,2   

  1. 1. Dept. of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao 266000, China
    2. School of Stomatology, Qingdao University, Qingdao 266000, China
    3. Dept. of Orthodontics, Affiliated Hospital of Jining Medical University, Jining 272000, China
    4. Dept. of Orthodontics, Yantai Stomatological Hospital, Yantai 264010, China
  • Received:2021-07-09 Revised:2021-11-10 Online:2022-03-01 Published:2022-03-15
  • Contact: Cunhui Fan
  • Supported by:
    This study was supported by “Clinical Medicine + X” Scientific Research Project of the Affiliated Hospital of Qingdao University(2020-2021)

RichHTML

13

PDF (PC)

79

摘要：

目的 研究替牙期骨性Ⅲ类单侧完全性唇腭裂（UCLP）患者和非唇腭裂骨性Ⅲ类患者牙弓形态的差异。方法 选取替牙期骨性Ⅲ类UCLP患者23例、非唇腭裂骨性Ⅲ类患者24例为试验组;年龄相仿的个别正常𬌗患者24例为对照组。在石膏模型上测量3组患者的牙弓宽度及长度。使用SPSS 26.0统计软件对数据进行统计分析。结果 1）UCLP组上颌裂隙侧牙弓宽度及长度均小于非裂隙侧（P<0.01）,骨性Ⅲ类组双侧差异无统计学意义（P>0.05）。2）UCLP组上颌裂隙侧牙弓宽度及长度小于骨性Ⅲ类组,2组均小于正常𬌗组（P<0.05）;上颌非裂隙侧牙弓长度小于骨性Ⅲ类,2组均小于正常𬌗组;上颌非裂隙侧牙弓宽度除尖牙区外,其余各段（前磨牙和磨牙区）与骨性Ⅲ类组差异无统计学意义（P>0.05）。3）UCLP组骨性Ⅲ类组下颌牙弓的宽度及长度差异无统计学意义（P>0.05）,均大于正常𬌗组（P<0.05）。结论 替牙期UCLP患者上颌牙弓较骨性Ⅲ类患者更窄、更短,且不对称;下颌牙弓在该期与骨性Ⅲ类患者尚无明显差异。对于UCLP反𬌗及牙弓缩窄患者的治疗应采取个性化、有针对性的差异性扩弓矫治方案。

关键词: 替牙期, 单侧完全性唇腭裂, 骨性Ⅲ类, 牙弓形态

Abstract:

Objective To explore the dental arch morphology between patients with unilateral complete cleft lip and palate (UCLP) and patients with non-cleft lip and palate with a classⅢskeletal relationship in mixed dentition stage. Methods The objects of study were 23 patients with skeletal classⅢUCLP and 23 patients with non-cleft skeletal class Ⅲ UCLP in mixed dentition stage who were enrolled as the experimental groups. The control group comprised 24 subjects of the same age with normal occlusion. Measurements were made for the width and length of the dental arch on the plaster model. SPSS 26.0 software was used for data analysis. Results 1) In the UCLP group, the width and length of the dental arch on the maxillary fissure side were smaller than those on the non-fissure side (P<0.01), but no statistical difference was found between the two sides in the skeletal classⅢgroup (P>0.05). 2) The width and length of the dental arch on the maxillary fissure side were less in the UCLP group than those in the skeletal group Ⅲ group while both were less in the former two experimental groups than those in the normal occlusion group (P<0.05). Meanwhile, the length of the dental arch on the maxillary non-fissure side was less than that in the skeletal class Ⅲ group, which was less in the former two experimental groups than that in the normal occlusion group. In addition, no statistical difference was found in the width of the dental arch when compared with the skeletal class Ⅲ group in the remaining areas, except for the canine zone (P>0.05). 3) There was no significant difference in the width and length of the mandibular arch between the two experimental groups (P>0.05), which were both larger in the former two experimental groups than those in the normal occlusion group (P<0.05). Conclusion The maxillary arch of the patients with UCLP in the mixed dentition stage is narrower, shorter, and more asymmetric than that of patients with skeletal classⅢUCLP while no significant difference is found in the mandibular arch between the patients with UCLP and patients with skeletal classⅢUCLP in the same stage. It is recommended that individualized and targeted differential arch expansion be adopted for the treatment of patients with UCLP combined with crossbite and intraversion.

Key words: mixed dentition, unilateral complete cleft lip and palate, skeletal class Ⅲ, arch morphology

中图分类号: 

  • R783.5

图1

标记点的确定及牙弓宽度、长度的测量= 左：确定测量标志点;中：牙弓长度;右：牙弓宽度;上：上颌;下：下颌。"

表 1

UCLP组双侧牙弓宽度及长度的比较"

测量项目 裂隙侧（n=23） 非裂隙侧（n=23） 差值 T值 P值
UW1 13.60±1.65 19.53±3.55 5.93 -7.385 0.000**
UW2 21.86±1.91 26.03±2.56 4.17 -9.315 0.000**
UW3 28.09±2.97 29.49±2.32 1.40 -3.083 0.005**
UL 29.05±2.03 29.99±2.26 0.94 -4.666 0.000**
LW1 17.01±2.10 16.70±1.99 -0.31 1.173 0.253
LW2 23.73±3.75 23.74±3.71 0.01 1.922 0.068
LW3 33.61±3.33 33.85±3.43 0.24 -0.909 0.373
LL 29.07±1.53 29.00±1.59 -0.07 0.360 0.722

表 2

UCLP组上颌裂隙侧、骨性Ⅲ类及正常??组牙弓宽度及长度的比较"

测量项目 UCLP组裂隙侧（n=23） 骨性Ⅲ类组（n=48） 正常??组（n=48） F值 P值
UW1 13.60±1.65ab 17.13±1.65a 18.77±3.43 32.558 0.000**
UW2 21.86±1.91ab 24.45±2.44a 27.62±1.85 62.980 0.000**
UW3 28.09±2.97ab 29.87±2.18a 34.89±2.65 73.450 0.000**
UL 29.05±2.03ab 30.30±1.40a 31.54±2.69 11.383 0.000**

表 3

UCLP组上颌非裂隙侧与骨性Ⅲ类及正常??组牙弓宽度及长度的比较"

测量项目 UCLP组非裂隙侧（n=23） 骨性Ⅲ类组（n=48） 正常??组（n=48） F值 P值
UW1 19.53±3.55ab 17.13±1.65a 18.77±3.43 6.667 0.002**
UW2 26.03±2.56a 24.45±2.44a 27.62±1.85 23.977 0.000**
UW3 29.49±2.32a 29.81±2.18a 34.89±2.65 65.656 0.000**
UL 29.99±2.26ab 30.30±1.40a 31.54±2.69 5.694 0.004**

表 4

UCLP与骨性Ⅲ类、正常??组下颌牙弓宽度及长度的比较"

测量项目 UCLP组裂隙侧（n=23） 骨性Ⅲ类组（n=48） 正常??组（n=48） F值 P值
LW1 16.50±2.30a 17.23±2.38a 15.89±3.27 3.380 0.038*
LW2 24.49±4.52a 26.53±2.94a 23.73±3.69 4.783 0.010*
LW3 33.05±4.47a 33.19±3.14a 31.63±2.46 5.407 0.006**
LL 28.75±1.71a 29.02±2.02a 27.03±2.74 5.146 0.007**
[1] Harikrishnan P, Balakumaran V. Analysis of intrama-xillary and mid-face skeletal asymmetry in a three-dimensional model with complete unilateral cleft lip and palate[J]. J Craniofac Surg, 2018, 29(8): e759-e762.
doi: 10.1097/SCS.0000000000004718
[2] Vyas T, Gupta P, Kumar S, et al. Cleft of lip and pa-late: a review[J]. J Family Med Prim Care, 2020, 9(6): 2621.
doi: 10.4103/jfmpc.jfmpc_472_20
[3] Vanderas AP. Incidence of cleft lip, cleft palate, and cleft lip and palate among races: a review[J]. Cleft Palate J, 1987, 24(3): 216-225.
[4] Wang MY, Yuan Y, Wang ZF, et al. Prevalence of orofacial clefts among live births in China: a syste-matic review and meta-analysis[J]. Birth Defects Res, 2017, 109(13): 1011-1019.
doi: 10.1002/bdr2.v109.13
[5] Abuhijleh E, Aydemir H, Toygar-Memikoğlu U. Th-ree-dimensional craniofacial morphology in unilate-ral cleft lip and palate[J]. J Oral Sci, 2014, 56(2): 165-172.
pmid: 24930754
[6] Cruz CV, Mattos CT, Maia JC, et al. Genetic polymorphisms underlying the skeletal class Ⅲ phenotype[J]. Am J Orthod Dentofacial Orthop, 2017, 151(4): 700-707.
doi: 10.1016/j.ajodo.2016.09.013
[7] McNamara JA Jr. A method of cephalometric evaluation[J]. Am J Orthod, 1984, 86(6): 449-469.
pmid: 6594933
[8] Caballero JT, Pucciarelli MGR, Pazmiño VFC, et al. 3D comparison of dental arch stability in patients with and without cleft lip and palate after orthodontic/rehabilitative treatment[J]. J Appl Oral Sci, 2019, 27: e20180434.
[9] Disthaporn S, Suri S, Ross B, et al. Incisor and molar overjet, arch contraction, and molar relationship in the mixed dentition in repaired complete unilate-ral cleft lip and palate: a qualitative and quantitative appraisal[J]. Angle Orthod, 2017, 87(4): 603-609.
doi: 10.2319/091916-698.1 pmid: 28195497
[10] Lacerda RHW, Vieira AR. Retrognathic maxilla in individuals born with oral clefts is due to intrinsic factors and not only due to early surgical treatment[J]. Angle Orthod, 2021, 91(2): 243-247.
doi: 10.2319/060620-521.1 pmid: 33351889
[11] 房晓旭, 范存晖. 口周力对唇腭裂患者牙颌发育影响的研究现状[J]. 口腔医学, 2019, 39(9): 840-843.
Fang XX, Fan CH. Research status of the effect of perioral muscle pressure on the development of teeth and jaw in patients with cleft lip and palate[J]. Sto-matology, 2019, 39(9): 840-843.
[12] 左森, 古力巴哈·买买提力. 乌鲁木齐地区替牙期单侧完全性唇腭裂患者修复术后气道形态与舌骨位置研究[J]. 实用口腔医学杂志, 2020, 36(4): 637-642.
Zuo S, Gulibaha M. A study of airway morphology and hyoid bone position after unilateral complete cleft lip and palate repair in patients with mixed dentition of Urumqi region[J]. J Pract Stomatol, 2020, 36(4): 637-642.
[13] 李巍然, 林久祥, 傅民魁. 唇腭裂术后反𬌗患者口周肌肌电图的研究[J]. 中华口腔医学杂志, 1994, 29(6): 342-345, 384.
pmid: 7743877
Li WR, Lin JX, Fu MK. Electromyography of perio-ral muscles in the cleft lipand palate patients with crossbite[J]. Chin J Stomatol, 1994, 29(6): 342-345, 384.
pmid: 7743877
[14] Jamilian A, Showkatbakhsh R, Boushehry MB. The effect of tongue appliance on the nasomaxillary complex in growing cleft lip and palate patients[J]. J Indian Soc Pedod Prev Dent, 2006, 24(3): 136-139.
pmid: 17065780
[15] Shi B, Losee JE. The impact of cleft lip and palate repair on maxillofacial growth[J]. Int J Oral Sci, 2015, 7(1): 14-17.
doi: 10.1038/ijos.2014.59
[16] 郭凌燕, 陈林林. 唇腭裂患者上颌骨生长发育影响因素的研究进展[J]. 实用临床医学, 2016, 17(1): 94-96.
Guo LY, Chen LL. Research progress on the influen-cing factors of maxillary growth and development in cleft lip and palate[J]. Pract Clin Med, 2016, 17(1): 94-96.
[17] 金群芳. 单侧唇腭裂患者术后恒牙列牙弓形态学分析[D]. 乌鲁木齐: 新疆医科大学, 2015.
Jin QF. Postoperative morphological characterristics of dental arch in patients with unilateral cleft lip and palate[D]. Urumqi: Xinjiang Medical University, 2015.
[18] Wahaj A, Ahmed I. Comparison of intercanine and intermolar width between cleft lip palate and normal class Ⅰ occlusion group[J]. J Coll Physicians Surg Pak, 2015, 25(11): 811-814.
[19] Gopinath VK, Samsudin AR, Mohd Noor SNF, et al. Facial profile and maxillary arch dimensions in unilateral cleft lip and palate children in the mixed dentition stage[J]. Eur J Dent, 2017, 11(1): 76-82.
doi: 10.4103/ejd.ejd_238_16 pmid: 28435370
[20] 高升辉, 姚军, 闫福华, 等. 福建省北部地区儿童牙弓宽度测量研究[J]. 中国实用口腔科杂志, 2009, 2(7): 412-414.
Gao SH, Yao J, Yan FH, et al. A study on the mea-surements of the dental arch width of the children in Fujian[J]. Chin J Pract Stomatol, 2009, 2(7): 412-414.
[21] 徐静, 张景慧. 青少年牙冠、牙弓大小与错𬌗畸形的关系[J]. 全科口腔医学电子杂志, 2015, 2(9): 20-21, 25.
Xu J, Zhang JH. Relationship between the size of dental crown and dental arch and malocclusion in adolescents[J]. Gen J Stomatol, 2015, 2(9): 20-21, 25.
[22] 田忠辉, 范存晖, 刘沂, 等. 替牙期单侧完全性唇腭裂患者下颌骨体积的测量分析[J]. 中国实用口腔科杂志, 2019, 12(5): 275-278.
Tian ZH, Fan CH, Liu Y, et al. Measurement and analysis of mandibular volume in patients with uni-lateral complete cleft lip and palate during mixed den-tition[J]. Chin J Pract Stomatol, 2019, 12(5): 275-278.
[23] 王宏扬, 范存晖, 杨茜, 等. 替牙期单侧完全性唇腭裂病人下颌骨对称性的锥形束CT观察[J]. 青岛大学医学院学报, 2017, 53(2): 174-176.
Wang HY, Fan CH, Yang Q, et al. Cone-beam com-puted tomography assessment of mandibular asym-metry in unilateral complete cleft lip and palate pa-tients during mixed dentition period[J]. Acta Acad Med Qingdao Univ, 2017, 53(2): 174-176.
[24] Shankar VA, Snyder-Warwick A, Skolnick GB, et al. Incidence of palatal fistula at time of secondary alveolar cleft reconstruction[J]. Cleft Palate Craniofac J, 2018, 55(7): 999-1005.
doi: 10.1597/16-179
[25] Liou EJ, Tsai WC. A new protocol for maxillary protraction in cleft patients: repetitive weekly protocol of alternate rapid maxillary expansions and constrictions[J]. Cleft Palate Craniofac J, 2005, 42(2): 121-127.
doi: 10.1597/03-107.1
[26] Dogan E, Seckin O. Maxillary protraction in patients with unilateral cleft lip and palate: evaluation of soft and hard tissues using the Alt-RAMEC protocol[J]. J Orofac Orthop, 2020, 81(3): 209-219.
doi: 10.1007/s00056-020-00220-y pmid: 32342120
[27] 李巍然. 唇腭裂的正畸治疗及长期稳定性[J]. 中华口腔医学杂志, 2018, 53(9): 585-589.
doi: 10.3760/cma.j.issn.1002-0098.2018.09.003 pmid: 30196616
Li WR. Stability of orthodontic treatment in the pa-tients with cleft lip and palate[J]. Chin J Stomatol, 2018, 53(9): 585-589.
doi: 10.3760/cma.j.issn.1002-0098.2018.09.003 pmid: 30196616
[28] Lin YF, Fu Z, Ma L, et al. Cone-beam computed tomography-synthesized cephalometric study of ope-rated unilateral cleft lip and palate and noncleft children with class Ⅲ skeletal relationship[J]. Am J Orthod Dentofacial Orthop, 2016, 150(5): 802-810.
doi: 10.1016/j.ajodo.2016.03.031
[29] Liu XY, Chen ZQ. Effects of palate repair on cranial base and maxillary morphology in patients with unilateral complete cleft lip and palate[J]. Cleft Palate Craniofac J, 2018, 55(10): 1367-1374.
doi: 10.1177/1055665618768544
[30] 邱赛男, 金作林, 李盛, 等. 已修复唇腭裂与骨性Ⅲ类成人患者颌骨差异[J]. 实用口腔医学杂志, 2018, 34(4): 522-525.
Qiu SN, Jin ZL, Li S, et al. Craniofacial difference between patients with cleft lip and palate after ana-plasty and those with skeletal classⅢmalocclusion[J]. J Pract Stomatol, 2018, 34(4): 522-525.
[31] Pegelow M, Alqadi N, Karsten AL. The prevalence of various dental characteristics in the primary and mixed dentition in patients born with non-syndro-mic unilateral cleft lip with or without cleft palate[J]. Eur J Orthod, 2012, 34(5): 561-570.
doi: 10.1093/ejo/cjr074
[32] Batwa W, Almarhoon HA, Almoammar KA, et al. Dento-skeletal characteristics of cleft patients with missing teeth[J]. Clin Cosmet Investig Dent, 2018, 10: 237-244.
doi: 10.2147/CCIDE
[33] Lai MC, King NM, Wong HM. Dental development of Chinese children with cleft lip and palate[J]. Cleft Palate Craniofac J, 2008, 45(3): 289-296.
doi: 10.1597/07-019
[34] 范新新, 李静, 葛立宏, 等. 非综合征性单侧完全性唇腭裂恒牙发育异常的研究[J]. 中华口腔医学杂志, 2011, 46(5): 263-266.
Fan XX, Li J, Ge LH, et al. Dental anomalies in Chinese children with complete unilateral cleft lip and palate[J]. Chin J Stomatol, 2011, 46(5): 263-266.
[35] Bartzela TN, Carels CE, Bronkhorst EM, et al. Tooth agenesis patterns in unilateral cleft lip and palate in humans[J]. Arch Oral Biol, 2013, 58(6): 596-602.
doi: 10.1016/j.archoralbio.2012.12.007
[36] Laing E, Ashley P, Naini FB, et al. Space maintenance[J]. Int J Paediatr Dent, 2009, 19(3): 155-162.
doi: 10.1111/j.1365-263X.2008.00951.x pmid: 19385999
[37] 朱万春, 许丽霞, 李双飞, 等. 唇腭裂患者患龋情况的调查[J]. 四川大学学报(医学版), 2007, 38(4): 697-700.
Zhu WC, Xu LX, Li SF, et al. Dental caries in chil-dren with cleft lip and/or palate in China[J]. J Sichuan Univ (Med Sci), 2007, 38(4): 697-700.
[38] 牟思璇, 朱妍菲, 杜常欣, 等. 改良牙支持式上颌骨前部牵引成骨术与上颌骨Le FortⅠ型前徙术对唇腭裂患者腭咽部结构的影响[J]. 中国口腔颌面外科杂志, 2020, 18(5): 427-433.
Mu SX, Zhu YF, Du CX, et al. Comparative study of modified tooth-borne anterior maxillary segmental distraction osteogenesis and Le FortⅠosteotomy on velopharyngeal structure changes in cleft lip palate patients[J]. China J Oral Maxillofac Surg, 2020, 18(5): 427-433.
[39] Zhang Z, Zhang P, Li S, et al. Skeletal, dental and facial aesthetic changes following anterior maxillary segmental distraction by tooth-borne device in patients with cleft lip and palate[J]. Int J Oral Maxillofac Surg, 2021, 50(6): 774-781.
doi: 10.1016/j.ijom.2020.09.010
[40] 李巍然, 林久祥, 傅民魁. 唇腭裂术后反𬌗与普通反𬌗畸形的牙颌、面形态结构比较研究[J]. 口腔正畸学杂志, 1994, 1(1): 13-16.
Li WR, Lin JX, Fu MK. A comparative study on the dental and maxillofacial morphology of cleft lip and palate after surgery[J]. Chin J Orthod, 1994, 1(1): 13-16.
[41] Sundareswaran S, Nipun CA. Glenoid fossa position in surgically repaired unilateral cleft lip and pa-late patients[J]. Eur J Orthod, 2015, 37(4): 386-390.
doi: 10.1093/ejo/cju065
[42] Celikoglu M, Buyuk SK, Ekizer A, et al. Evaluation of mandibular transverse widths in patients affected by unilateral and bilateral cleft lip and palate using cone beam computed tomography[J]. Angle Orthod, 2015, 85(4): 611-615.
doi: 10.2319/061614-438.1 pmid: 25230812
[43] Singh GD, Rivera-Robles J, de Jesus-Vinas J. Longitudinal craniofacial growth patterns in patients with orofacial clefts: geometric morphometrics[J]. Cleft Palate Craniofac J, 2004, 41(2): 136-143.
doi: 10.1597/02-166 pmid: 14989692
[44] 傅民魁. 口腔正畸学[M]. 北京: 人民卫生出版社, 2012: 244.
Fu MK. Orthodontics[M]. Beijing: People’s Medical Publishing House, 2012: 244.
[45] 林倚帆, 马莲, 李巍然. 骨性Ⅲ类替牙期单侧完全性唇腭裂与非唇腭裂患者颅面结构比较[C]// 中华口腔医学会口腔正畸专业委员会. 2016中国国际正畸大会暨第十五次全国口腔正畸学术会议论文汇编. 北京: 中华口腔医学会口腔正畸专业委员会, 2016: 2.
Lin YF, Ma L, Li WR, et al. Cone-beam computed tomography-synthesized cephalometric study of ope-rated unilateral cleft lip and palate and noncleft chil-dren with classⅢskeletal relationship[C]// Oral Or-thodontic Committee of Chinese Stomatological As-sociation. 2016 China International Orthodontic Con-ference and the 15th National Conference on Ortho-dontics. Beijing: Orthodontic Committee of Chinese Stomatological Association, 2016: 2.
[1] 潘颖丹, 刘艺琴, 肖立伟. 替牙期唇腭裂患者的正畸治疗[J]. 国际口腔医学杂志, 2017, 44(4): 380-384.
[2] 田静 1 高辉 2 刘颖 1 孙留振 3 肖丹娜 2. 骨性Ⅲ类错畸形患者前牙弓形态的特征分析[J]. 国际口腔医学杂志, 2013, 40(2): 156-159.
[3] 张林 段沛沛综述 陈扬熙审校. 正畸弓丝形态的研究进展[J]. 国际口腔医学杂志, 2012, 39(2): 273-276.
[4] 崔洲迎, 赖文莉, 蒋兴棵, 张颖敏. 2×4 矫治技术矫正替牙期前牙反的临床分析[J]. 国际口腔医学杂志, 2009, 36(3): 285-287.
[5] 徐蕾,丁寅. 唇挡对替牙期下颌牙弓的作用[J]. 国际口腔医学杂志, 2001, 28(02): -.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] 王昆润. 修补颌骨缺损的新型生物学相容材料[J]. 国际口腔医学杂志, 1999, 26(06): .
[2] 陆加梅. 不可复性关节盘移位患者术前张口度与关节镜术后疗效的相关性[J]. 国际口腔医学杂志, 1999, 26(06): .
[3] 王昆润. 咀嚼口香糖对牙周组织微循环的影响[J]. 国际口腔医学杂志, 1999, 26(06): .
[4] 宋红. 青少年牙周炎外周血分叶核粒细胞的趋化功能[J]. 国际口腔医学杂志, 1999, 26(06): .
[5] 高卫民,李幸红. 发达国家牙医学院口腔种植学教学现状[J]. 国际口腔医学杂志, 1999, 26(06): .
[6] 侯锐. 正畸患者釉白斑损害的纵向激光荧光研究[J]. 国际口腔医学杂志, 1999, 26(05): .
[7] 轩东英. 不同赋形剂对氢氧化钙抗菌效果的影响[J]. 国际口腔医学杂志, 1999, 26(05): .
[8] 房兵. 唇腭裂新生儿前颌骨矫正方法及对上颌骨生长发育的影响[J]. 国际口腔医学杂志, 1999, 26(05): .
[9] 杨美祥. 前牙厚度在预测上下颌牙量协调性中的作用[J]. 国际口腔医学杂志, 1999, 26(04): .
[10] 赵艳丽. 手术刀、电凝、CO_2和KTP激光对大鼠舌部创口的作用[J]. 国际口腔医学杂志, 1999, 26(04): .