国际口腔医学杂志 ›› 2020, Vol. 47 ›› Issue (3): 304-310.doi: 10.7518/gjkq.2020019

• 综述 • 上一篇    下一篇

中性粒细胞细胞外陷阱网与牙周炎的相关性研究进展

王晓宇,朱昭蓉,吴亚菲,赵蕾()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心四川大学华西口腔医院牙周病科 成都 610041
  • 收稿日期:2019-06-11 修回日期:2019-10-31 出版日期:2020-05-01 发布日期:2020-05-08
  • 通讯作者: 赵蕾 E-mail:jollyzldoc@163.com
  • 作者简介:王晓宇,硕士,Email:492742363@qq.com
  • 基金资助:
    国家自然科学基金面上项目(81970944);四川省重点研发项目(2018SZ0161)

Advances in research on the relationship of neutrophil extracellular traps to periodontitis

Wang Xiaoyu,Zhu Zhaorong,Wu Yafei,Zhao Lei()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2019-06-11 Revised:2019-10-31 Online:2020-05-01 Published:2020-05-08
  • Contact: Lei Zhao E-mail:jollyzldoc@163.com
  • Supported by:
    The General Program of National Natural Science Foundation of China(81970944);Reasher and Development Project of Sichuan Province(2018SZ0161)

摘要:

中性粒细胞是机体防御系统的成员之一,在免疫反应中发挥着重要作用。中性粒细胞细胞外陷阱网(NET)是新近发现的中性粒细胞发挥作用的一种形式,除了能够诱获并杀灭病原体而发挥作用之外,还可能对机体产生直接或者间接的损伤。NET不仅出现在牙周组织中,还与牙周致病菌息息相关。本文对NET与牙周炎的相关性研究进行综述。

关键词: 中性粒细胞细胞外陷阱网, 中性粒细胞, 牙周炎, 牙周致病菌

Abstract:

Neutrophil is a member of the body’s defence system and plays an important role in immune responses. Neutrophil extracellular trap (NET) is a newly discovered form of functioning neutrophil that can trap and kill pathogens and may cause direct or indirect damage to the body. NETs not only appear in periodontal tissues but are also closely related to periodontal pathogens. This article will review related research on NETs and periodontitis.

Key words: neutrophil extracellular trap, neutrophil, periodontitis, periodontal pathogen

中图分类号: 

  • R781.4 +2
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