国际口腔医学杂志 ›› 2019, Vol. 46 ›› Issue (2): 186-190.doi: 10.7518/gjkq.2019023
吕慧欣1,杜留熠1,王鹞1,于维先2,任静宜1,顾芯铭1,周延民1()
Huixin Lü1,Liuyi Du1,Yao Wang1,Weixian Yu2,Jingyi Ren1,Xinming Gu1,Yanmin Zhou1()
摘要:
炎症小体是存在于细胞质的多蛋白质复合物,参与机体的固有免疫反应,活化促炎因子白细胞介素-1β等介导了细胞的死亡,对炎症的进程有重要的调控作用。牙周炎是由多种牙周病致病菌(例如牙龈卟啉单胞菌)引起的炎性破坏性疾病。细菌菌体以及其毒性成分可以引发多种炎症小体的聚集组装,最终导致牙周组织的破坏等变化。本文将就机体发生牙周炎过程中炎症小体的产生和致病机制进行综述。
中图分类号:
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