CD24在口腔医学中的研究进展

doi:10.7518/gjkq.2017.05.023

国际口腔医学杂志 ›› 2017, Vol. 44 ›› Issue (5): 608-613.doi: 10.7518/gjkq.2017.05.023

CD24在口腔医学中的研究进展

梁静¹, 王凯¹, 吴家媛^{1, 2}

1.遵义医学院口腔学院遵义 563099;
2.贵州省高等学校口腔疾病研究特色重点实验室遵义 563099

收稿日期:2016-12-19 修回日期:2017-05-15 出版日期:2017-09-01 发布日期:2017-09-01
通讯作者: 吴家媛,副教授,博士,Email：wujiayuan@zmc.edu.cn
作者简介:梁静,住院医师,硕士,Email：845892497@qq.com
基金资助:
国家自然科学基金（81460102）; 贵州省省长基金（[2012]- 16）; 贵州省遵义市红花岗基金（[2012]07）; 贵州省科技创新人才团队资助（[2013]4026）; 贵州省高等学校特色重点实验室建设项目（[2013]109）

Research progress on CD24 in stomatology

Liang Jing¹, Wang Kai¹, Wu Jiayuan^{1, 2}

1. School of Stomatology, Zunyi Medical University, Zunyi 563099, China;
2. Special Key Laboratory of Oral Diseases Research, Institutions of Higher Learning in Guizhou Province, Zunyi 563099, China

Received:2016-12-19 Revised:2017-05-15 Online:2017-09-01 Published:2017-09-01
Supported by:
; This study was supported by National Natural Science Foundation of China(81460102), Governor Foundation of Guizhou Province([2012]16), Zunyi Honghuagang Science Foundation of Guizhou Province([2012]07), Science Innovative Team Foundation of Guizhou Province([2013]4026) and Special Laboratory Construction Foundation of Higher Education of Guizhou Province([2013]109).

摘要/Abstract

摘要： CD24分子是细胞表面的一种糖蛋白,可表达于多种细胞,如前体B细胞、T细胞、神经细胞、肌细胞及肿瘤细胞等。近年来,科学家们针对CD24在医学研究中的重要表现做了大量研究,发现在炎症、肿瘤及干细胞等领域中均有CD24的参与。尽管CD24的功能尚不清楚,但有研究提示它参与了部分口腔疾病的发生和发展。故此文针对CD24在口腔医学领域的相关研究作一总结,以促进该领域研究的进一步发展。

关键词: CD24, 口腔医学, 牙周病, 自身免疫性疾病, 口腔肿瘤

Abstract: CD24 is a cell surface glycoprotein expressed in pre-B cells, T cells, neurons, muscle cells, and carcinoma cells. Many researchers reported that CD24 plays an important role in inflammation, autoimmune diseases, and cancer. The function of this protein remains unclear. However, CD24 may be involved in various oral diseases. Hence, this study summarizes major findings associated with CD24 to stimulate new ideas that can be used for further research and reveal underlying links among diverse processes mediated by CD24.

Key words: CD24, stomatology, periodontal disease, autoimmune disease, oral tumor

中图分类号:

梁静, 王凯, 吴家媛. CD24在口腔医学中的研究进展[J]. 国际口腔医学杂志, 2017, 44(5): 608-613.

Liang Jing, Wang Kai, Wu Jiayuan. Research progress on CD24 in stomatology[J]. Inter J Stomatol, 2017, 44(5): 608-613.

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CD24在口腔医学中的研究进展

Research progress on CD24 in stomatology

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