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20 January 2011, Volume 38 Issue 1 Previous Issue    Next Issue

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Research progress on maxillary sinus floor elevation surgery ZHOU Lei. Inter J Stomatol. 2011, 38 (1):  1-6.  DOI: 10.3969/j.issn.1673-5749.2011.01.001 Abstract ( 1764 )   HTML ( 17 )   PDF（pc） (484KB) ( 3288 )   Save Maxillary sinus elevation surgery is a most effective and reliable procedure to increase the height of bone available for implant placement in the posterior maxilla. Based on our clinical experiences and the reports in the international literature, the most commonly used techniques and their advantages and disadvantages were discussed in this paper. Sinus floor elevation with simultaneously implant placement could shorten the treatment time and make the treatment more simple. It’s a topic that worth to study, the development of this modality and our experiences are introduced as well. Related Articles | Metrics

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Expression of vascular endothelial growth factor-C in squamous cell carcinoma of the tongue with dif FENG Zheng-Hu, LI Chun-Qing, WANG Ling, HAN Bing, NIE Hong-Bing, SU Xue-Lian Inter J Stomatol. 2011, 38 (1):  7-9.  DOI: 10.3969/j.issn.1673-5749.2011.01.002 Abstract ( 1572 )   HTML ( 2 )   PDF（pc） (242KB) ( 834 )   Save Objective  To study the vascular endothelial growth factor（VEGF）-C expression in squamous cell carcinoma of the tongue with different pattern of invasion. Methods  39 cases with squamous cell carcinoma of the tongue were classified into four groups according to the pattern of invasion described by Anneroth and VEGFC expression was detected respectively by using immunohistochemical staining. Results  The expression of VEGFC in tumor cells varied from the pattern of invasion. The expression in squamous cell carcinoma of the tongue with pattern Ⅲ and Ⅳ of invasion had a high lever than that of pattern Ⅰand Ⅱ. The clinical findings showed that the rate of lymph node metastasis was easily involved in pattern Ⅲ and Ⅳ of invasion. Conclusion VEGFC is correlated with pattern of invasion and it may play an important role in invasion and regional lymph node metastasis in squamous cell carcinoma of the tongue. Related Articles | Metrics

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Cobalt-chromium alloy and titanium abutments and all -ceramic crowns bonding interface between the t WANG Wei-jia1, LONG Gang2, HU Jia-wei3, HE Rui -hua4, SUN Yong4. Inter J Stomatol. 2011, 38 (1):  10-13.  DOI: 10.3969/j.issn.1673-5749.2011.01.003 Abstract ( 1590 )   HTML ( 4 )   PDF（pc） (309KB) ( 1145 )   Save Objective   By comparing the observed cobalt-chromium alloy and titanium abutment abutment supported all-ceramic crowns with three kinds of composite resin bonding between the interface stress distribution to the difference between cobalt-chromium alloy to observe the characteristics of base stations. Methods   Mandibular first molar implants local structure of three-dimensional finite element model to simulate the maximum bite force at the crown teeth occlusal surface horizontal and vertical force loading. Results   Cobalt-chromium alloy on bonding interface of base stations was less than the stress of titanium abutment interface and a more uniform stress distribution in the region wide, cobalt-chromium alloy with titanium bonding interface of base stations as base stations, the horizontal loading force much larger than the maximum vertical load and, stress concentration, mainly in the neck and base stations and the crown implant junction. Cobalt-chromium alloy on bonding interface of base stations, the maximum stress concentration than the titanium abutment interface was smalland wide distribution. Conclusion   Cobalt-chromium alloy bond stress distribution of base stations is better than titanium abutment interface. Cobalt-chromium alloy on bonding interface of base stations is relatively more resistant titanium abutment fracture. Cobalt-chromium alloy on bonding interface of base stations, base station interface with titanium as similar to the stress distribution. In clinical applications, cobalt-chromium alloy is a titanium abutment of base stations a useful complement. Related Articles | Metrics

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Platelet-rich plasma generated via the three centrifugalization method and its impact on adipose tis XU Yan, YE Mei, CHEN Fang, JIANG Da-Chuan, SUN Xiao-Yu, LIN Xiao, SHEN Ji-Long Inter J Stomatol. 2011, 38 (1):  14-18.  DOI: 10.3969/j.issn.1673-5749.2011.01.004 Abstract ( 1507 )   HTML ( 5 )   PDF（pc） (269KB) ( 1935 )   Save Objective  The study investigated an effective method of generating platelet-rich plasma（PRP） and evaluated the impact of different concentrations of PRP on adipose tissue-derived stem cell（ADSC） proliferation and mineralization in vitro. Methods  40 mL whole blood was collected from 3 healthy Beagle dogs and then PRP was separated by the two centrifugalization method and the three centrifugalization method respectively. Then the platelet was counted and analyzed. ADSC were exposed to DMEM medium with various concentrations of PRP （5%, 10%, 15%, 20%） respectively. After incubation of 48, 72, 96 h, the proliferations of ADSC were measured. ADSC were cultured in osteoblasts induced medium and osteoblasts induced medium with PRP（5%, 10%, 15%, 20%） respectively, The osteogenetic expression of ADSC and the influence on its osteogenesis mineralization of PRP were observed. Results   The number of platelet from the three centrifugalization method was more than that from the two centrifugalization method. The role on various concentrations of PRP on cell proliferation was more significant than that of negative control（P<0.001）, the differences between various concentrations of PRP groups had a statistical significance（P<0.001）. The group of 96 h, 15% PRP reached to pe ak value in ADSC proliferation. The quantity of mineralization node in ADSC was maximized under the condition of osteoblasts induced medium with 20% PRP. Conclusion   The three centrifugalization method was more efficient than the two centrifugalization method. PRP promoted ADSC proliferation in both the dose- and time- dependent ways while PRP improved ADSC mineralization in the dose-dependent way only. Related Articles | Metrics

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Three-dimensional finite element analysis on the effect of root canal size on fracture ZHANG Yan1,2, QIN Xiao-hong2, YAO Ji3, LI Sha-sha2, ZHANG Li-jie3. Inter J Stomatol. 2011, 38 (1):  19-21.  DOI: 10.3969/j.issn.1673-5749.2011.01.005 Abstract ( 1085 )   HTML ( 2 )   PDF（pc） (136KB) ( 721 )   Save Objective To evaluate the effects of root canal size on the distribution of the stress located on the root. Methods A three-dimensional finite element model of maxillary second premolar（single tube） was created, by varying the root canal size to analyze the distribution of the stress located on different root models. Results The root canal size slightly affected the stress level. The stress variety located on the coronal 1/3 of the root. Conclusion The results suggest that clinical root canal treatment should be just removing the infected tissue and avoiding over-cutting of dentin, root canal preparation no more than 1/3 of the original root canal is secure. Related Articles | Metrics

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Study on the clinical application of contralateral primary tumor submental island flap to reconstruct oral and maxillofacial defects PAN Meng-xiong, MA Xiang-wei, QIN Xiao-rong, MAO Jun-wu, LI Bo, LIU Zhiqiang. Inter J Stomatol. 2011, 38 (1):  22-23.  DOI: 10.3969/j.issn.1673-5749.2011.01.006 Abstract ( 1100 )   HTML ( 1 )   PDF（pc） (220KB) ( 751 )   Save Objective To explore the method that uses primary tumor contralateral submental island flap to reconstruct tongue and floor of mouth defects. Methods Selected 5 cases that used primary tumor contralateral submental island flap to reconstruct tongue and floor of mouth defects after tumor resection, and observed the clinical efficacy. Results The submental island flap has a long pedicle, which can reach contralateral tongue and floor of mouth if required. All flaps were survived postoperative. Conclusion Contralateral primary tumor submental island flap has many features include: Easy obtaining and high survival rate with minimal donor site morbidity. It does not affect the radical, so it will be an ideal material for repairing tongue and floor of mouth defects. Related Articles | Metrics

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Clinical use of spiral CT in locating impacted teeth ZHOU Yan-ling, LI Na, MI Chang-jiang, MI Fang-lin. Inter J Stomatol. 2011, 38 (1):  24-26.  DOI: 10.3969/j.issn.1673-5749.2011.01.007 Abstract ( 1010 )   HTML ( 1 )   PDF（pc） (43KB) ( 579 )   Save Objective To discuss the clinical value of spiral CT in locating impacted teeth. Methods 23 cases with impacted teeth were examined with spiral CT scanning, which was to demonstrate the shape and location of impacted teeth and their relationship with neighbor teeth by means of three dimensional construction including multiplanar reconstruction（MPR）, surface shaded display（SSD） and volume rendering（VR）. Results There were 28 impacted teeth in 23 patients. The number of impacted teeth, shape, labial or palatal lacation, eruption orientation and their relationship to adjacent teeth could be clearly demonstrate on the reconstructed three dimensional images. Conclusion The combination of CT axial images with different reconstructions is an accurate and effective method to examine impacted teeth. Related Articles | Metrics

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Flexural strength of dental resin with differently made diamonds CHU Ya-qing1, TONG Yi1, WANG Xinzhi2, Inter J Stomatol. 2011, 38 (1):  27-30.  DOI: 10.3969/j.issn.1673-5749.2011.01.008 Abstract ( 1029 )   HTML ( 2 )   PDF（pc） (705KB) ( 815 )   Save Objective The purpose of this study was to assess the effects of differently synthesized diamonds on the flexural strength of dental resins. Methods Three groups resins were prepared in the same modify and compound process respectively with uniform quantity of detonation nanodiamond（DND）, still pressure diamond（SPD）, and polycrystalline diamond（PCD）. Resin without diamond was prepared as reference sample. Flexural strength of the four groups resins were measured by the method outlined in YY1042-2003. Results Flexural strength increases by 117.2% and 103.1% with the accession of DND and SPD. PCD unsignificantly enhances resin’s flexural strength. Conclusion Obvious increases in flexural strength are observed separately in resins with DND and SPD, and both the two flexural strengthes increase more than double; PCD has no remarkable effect on flexural strength of resin. Related Articles | Metrics

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Effects of titanium nitride coating on wear resistance of cast titanium TONG Yu1, GUO Tian-wen2, XIAO Hui-jun3, WANG Jing2, LIANG Hai-feng4. Inter J Stomatol. 2011, 38 (1):  31-33.  DOI: 10.3969/j.issn.1673-5749.2011.01.009 Abstract ( 1125 )   HTML ( 2 )   PDF（pc） (551KB) ( 691 )   Save Objective To evaluate the effects of titanium nitride（TiN） coating on surface microhardness and wear resistance of cast titanium. Methods TiN film was deposited on cast titanium using closed field unbalanced magnetron sputtering（CFUBMS）, after that microhardness and wear resistance of the cast titanium specimens were characterized by hardness testing and friction and wear test respectively. Results After TiN films were deposited on cast titanium, its microhardness increased significantly, wear volume and friction coefficient decreased significantly. Conclusion CFUBMS TiN coating can protect cast titanium from abrasion excessively. Related Articles | Metrics

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Clinical effects on injury caused dental pulp exposure with root canal filling in one time and fiber post immediate restoration LIU Rui-jie. Inter J Stomatol. 2011, 38 (1):  34-35.  DOI: 10.3969/j.issn.1673-5749.2011.01.010 Abstract ( 1133 )   HTML ( 2 )   PDF（pc） (75KB) ( 809 )   Save Objective To evaluate the clinical effects of root canal filling in one time fiber post immediate restoration when injury caused dental pulp exposure. Methods 30 patients with 49 teeth were involved. After complete root canal therapy, teeth were treated with fiber post and porcelain-fused-to-metal crown. The occurrence of pain after treatment and the effects after two years were observed. Results Five teeth occured medium pain after treatment in 24 hours. After two years, three teeth had root apical inflammation. One fiber post fractured. Conclusion The effects of root canal filling in one time and fiber post immediate restoration when injury caused dental pulp exposure is ideal. Related Articles | Metrics

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Research advances of tissue engineering bone on repairing of alveolar cleft ZHANG Dong-jie, QIAN Yufen. Inter J Stomatol. 2011, 38 (1):  36-39.  DOI: 10.3969/j.issn.1673-5749.2011.01.011 Abstract ( 980 )   HTML ( 1 )   PDF（pc） (171KB) ( 478 )   Save Alveolar cleft is a common congenital developmental defect accompanied with cleft lip and palate. In order to eliminate oronasal fistula, improve the periodontal condition of the teeth adjacent to the cleft and provide bone support during the period of teeth eruption, secondary bone grafting is needed as an essential procedure for alveolar cleft patients. Fresh autogenous bone from appropriate sites（i.e. iliac crest） is the“gold standard”for alveolar cleft osteoplasty, however it is often related to the disadvantages such as limited availability, donor site morbidity, repeated operations due to the absorption of the grafted bone and bone growth of the patients, all of these impose a heavy burden for the patients. To overcome these limitations, tissue engineering bone has provided predictable results with minimal donor-site morbidity. Here we review the three prerequisites consist of cell, scaffold, signaling molecular for tissue engineering and illustrate the relationship between tissue engineering bone and orthodontics for alveolar cleft. Related Articles | Metrics

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Biological property of Streptococcus mutans surface protein LIU Jiao-jiao, CHU Bing-feng, WANG Chenglong. Inter J Stomatol. 2011, 38 (1):  40-43.  DOI: 10.3969/j.issn.1673-5749.2011.01.012 Abstract ( 1210 )   HTML ( 3 )   PDF（pc） (155KB) ( 632 )   Save Streptococcus mutans has been implicated as a primary causative agent of dental caries in humans. And its cell surface protein is known to be one of the significant virulence factors, which has a strong relationship with cariogenic characteristic. This review paid attention to the research progress of biological property, molecular cloning of the encoding gene, main structure and function of the surface protein, in order to provide some reference for further studies about etiology and prevention of dental caries. Related Articles | Metrics

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Research progress on stress tolerance mechanisms by Streptococcus mutans JIANG Wei, LIANG Jing-ping. Inter J Stomatol. 2011, 38 (1):  44-47.  DOI: 10.3969/j.issn.1673-5749.2011.01.013 Abstract ( 1084 )   HTML ( 1 )   PDF（pc） (144KB) ( 726 )   Save Oral cavity is a complex and ever-changing environment. Living in oral cavity have to deal with sudden changes at any time in the environment to ensure its survival and normal physical activities. This is also the prerequisite of cariogenic bacterials when they play cariogenic virulence. Here is a review about research progress on how Streptococcus mutans withstand pressures in the oral environment, including changes in catabolic pathways, membrane remodeling and membrane proton translocating adenosine triphosphatase, urease and malate fermentation, gene regulation, and changes in protein. Related Articles | Metrics

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Research progress on tidemark of mandibular condylar cartilage CHEN Si1, LONG Xing1,2. Inter J Stomatol. 2011, 38 (1):  48-50.  DOI: 10.3969/j.issn.1673-5749.2011.01.014 Abstract ( 1247 )   HTML ( 1 )   PDF（pc） (143KB) ( 1273 )   Save As a junction between mature calcified cartilage and non-calcified cartilage, tidemark attracts more attention on researches about age -related changes, remodification, degeneration and repair in articular cartilage. However, detailed study of tidemark on mandibular condyle was rare. The purpose of this review is to provide a summary of research progress related to morphology and function of tidemark in mandibular condyle and hyaline articular cartilage which is health or suffering osteoarthrosis. Related Articles | Metrics

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Research progress on secreted aspartyl proteinase -2 LIN Yan, ZHAO Wei. Inter J Stomatol. 2011, 38 (1):  51-54.  DOI: 10.3969/j.issn.1673-5749.2011.01.015 Abstract ( 1056 )   HTML ( 2 )   PDF（pc） (148KB) ( 877 )   Save The secreted aspartyl proteinase（Sap）-2 is required for growth of the fungus and is a virulence factor. Moreover, Sap-2 is known to induce antibody response during Saccharomyces albicans infection. Sap-2 is involved in many aspects of pathogenic process. The origin, structure, biological characteristics, expression, influence factors, the mechanism of pathogenicity and application will be reviewed in this paper. Related Articles | Metrics

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Cre/loxP site -specific recombination system and its application in the field of oral medicine ZHANG Wen-juan, YU Dan-ni. Inter J Stomatol. 2011, 38 (1):  55-58.  DOI: 10.3969/j.issn.1673-5749.2011.01.016 Abstract ( 1184 )   HTML ( 3 )   PDF（pc） (147KB) ( 1468 )   Save Cre/loxP system is composed of Cre recombinase and loxP site. Cre recombinase can recognize loxP site and catalyze precise site-specific recombination of DNA between two loxP sites. The Cre/loxP system can modificate the genes in specific time and site, which acts in simple mode and recombinates in high efficiency. It has become an important tool for experiments that can be used to change the genetic information directionally in vivo. In this article, the structure, the mechanism of the recombination, the characteristics of Cre/loxP system and its application in the field of oral medicine have mainly been reviewed. Related Articles | Metrics

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Research progress on major histocompatibility complex classⅠchain-related protein A-natural killer group 2 member D passageway in head and neck squamous cell carcinoma LI Chao, JIANG Can-hua, JIAN Xin-chun. Inter J Stomatol. 2011, 38 (1):  59-62.  DOI: 10.3969/j.issn.1673-5749.2011.01.017 Abstract ( 960 )   HTML ( 2 )   PDF（pc） (148KB) ( 613 )   Save As the ligand of natural killer group 2 member D（NKG2D）, major histocompatibility complex classⅠ chain-related protein A（MICA） can combine with NKG2D to activate immunosurveillance mechanism of nature killer cells. This review concludes the research advances concerning the expression and regulation of the MICANKG2D passageway, and their expression in head and neck squamous cell carcinoma from the latest five years papers. Related Articles | Metrics

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Research progress on chromosome gene locus on the nonsyndromic cleft lip with or without cleft palate ZHUGE Xu-qing, ZHENG Qian. Inter J Stomatol. 2011, 38 (1):  63-66.  DOI: 10.3969/j.issn.1673-5749.2011.01.018 Abstract ( 1183 )   HTML ( 2 )   PDF（pc） (141KB) ( 964 )   Save Cleft lip with or without cleft palate（CL/P） is one of the most common congenital deformity which is considered as a combination factors of genetic and environment. More risked genes have been found under the great development of the molecular genetics. This context is a review on the novest CL/P-linked research about the locus of the risk candidate genes on the chromosomes. Related Articles | Metrics

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Research progress on Numb protein inhibiting tumorigenesis HAN Bang-feng, LI Long-jiang. Inter J Stomatol. 2011, 38 (1):  67-70.  DOI: 10.3969/j.issn.1673-5749.2011.01.019 Abstract ( 938 )   HTML ( 2 )   PDF（pc） (141KB) ( 747 )   Save Numb is a factor of cell fate determinant, which, by asymmetrically partitioning at mitosis, controls cell fate choices by antagonising the activity of the plasma membrance receptor of the Notch family. Numb has recently been shown to help activate the tumor suppressor protein p53. Loss of numb would result, therefore, in both the activation of the potential oncogene notch and the diminution of tumor suppression by p53. Here, we review the structure and function of Numb, Numb-related molecules and the relationship between Numb and tumor. Related Articles | Metrics

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Application of peripheral blood-derived multipotent mesenchymal stromal cells in bone tissue engineering HAN Xue, LIU Hong-chen. Inter J Stomatol. 2011, 38 (1):  71-74.  DOI: 10.3969/j.issn.1673-5749.2011.01.020 Abstract ( 973 )   HTML ( 2 )   PDF（pc） (179KB) ( 680 )   Save Peripheral blood-derived multipotent mesenchymal stromal cells circulate in low number. They share most of the surface markers with bone marrow-derived multipotent mesenchymal stromal cells, possess diverse and complicated gene expression characteristics. Although their origin and physio-pathological function are still unclear, their presence in the adult peripheral blood might relate to controversial subjects in the field of tissue engineering. In this review, current studies about peripheral blood-derived multipotent mesenchymal stromal cells are summarized, and its application in bone tissue engineering is discussed. Related Articles | Metrics

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Technologies of suppression subtractive hybridization and DNA chip technique and their applications in dental pulp studies WU Yu1，2, ZHOU Xue-dong1. Inter J Stomatol. 2011, 38 (1):  75-78.  DOI: 10.3969/j.issn.1673-5749.2011.01.021 Abstract ( 923 )   HTML ( 2 )   PDF（pc） (141KB) ( 481 )   Save Temporal and spatial distinct patterns of gene expression regulate biological processes involved in cell development, differentiation, cell cycle, death and pathology. The identification of differential expression gene between the different functional status cells has become an important content of gene research. In recent years, a variety of methods have been developed for analying differentially expressed genes, including subtractive hybridization, mRNA differential display, representational difference analysis, serial analysis of gene expression, suppression subtractive hybridization, expressed sequence tags, DNA chip, quantitative polymerase chain reaction and semiquantitative polymerase chain reaction. This manuscript reviews the two most commonly used technologies of rapid and large-scale screening for differentially expressed genes, and highlights recent applications in dental pulp studies. Related Articles | Metrics

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Study methods of the dental-maxillo-facial growth and development ZHANG Qiang1, CHEN Yang-xi2. Inter J Stomatol. 2011, 38 (1):  79-82.  DOI: 10.3969/j.issn.1673-5749.2011.01.022 Abstract ( 1294 )   HTML ( 3 )   PDF（pc） (158KB) ( 1166 )   Save The knowledge about cranio-maxillo-facial growth and development is an important part of orthodontic theories. People from different nations, regions, and genders have various patterns of craniofacial structure and occlusions, and the research about facial growth is complicated and difficult. Along with the advancement of technology, the studies on cranio-maxillo-facial growth develop from cross-sectional study to long-term longitudinal study, from 2-demensional to 3-demensional information acquisition. And the developing computer technique and software make the research more intensive. Such studies help our orthodontists to make precissive prediction of growth and clinic judgement. This topic is to overview the recent methods of studying cranio-maxillo-facial development. Related Articles | Metrics

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Research progress on chitin and its derivatives in repair of bone defect ZHOU Hong-bo, ZHU Zhi-min. Inter J Stomatol. 2011, 38 (1):  83-86.  DOI: 10.3969/j.issn.1673-5749.2011.01.023 Abstract ( 1009 )   HTML ( 2 )   PDF（pc） (133KB) ( 830 )   Save At the present, the main approach to repair the maxillary and facial malformation and dysfunction caused by bone defect is bone graft. Many researches focus on seeking for an ideal repair material. Chitin and its derivatives are a kind of native polymer. They have the potential to be an ideal repair material because of their special molecular structure and excellent biological characteristics. In this article, the recent studies on the application of chitin and its derivatives for repair of bone defect are reviewed. Related Articles | Metrics

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Advance in tooth colour measurement QIAN Jie-lei1, HUANG Jing1, LU Er-yi2. Inter J Stomatol. 2011, 38 (1):  87-90.  DOI: 10.3969/j.issn.1673-5749.2011.01.024 Abstract ( 1106 )   HTML ( 5 )   PDF（pc） (137KB) ( 1383 )   Save Accurate tooth color measurements play an important role in successful prosthesis. With the development of technology, various methods of colour matching emerge one after another, as well as related researches. This review will focus on the advance of tooth colour measurements including visual, colorimeter and digital image shade matching. Related Articles | Metrics

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Advances in application of cone beam CT in diagnosis and treatment of temporomandibular joint diseases LI Chun-jie1, JIA Yuan-yuan2, WANG Hu3, SHI Zong-dao1. Inter J Stomatol. 2011, 38 (1):  91-94.  DOI: 10.3969/j.issn.1673-5749.2011.01.025 Abstract ( 1167 )   HTML ( 2 )   PDF（pc） (141KB) ( 1494 )   Save Cone beam CT（CBCT） has been used more and more in the diagnosis and treatment of temporomandibular joint diseases in recent years. CBCT has great advantages in detecting and evaluating the osseous and joint space changes of the temporomandibular joint in different directions and aspects. It provides a new platform and a new approach in improving diagnostic accuracy and selection of rational treatment methods. This article introduces progress on the application of CBCT in diagnosing and treatment of temporomandibular joint diseases and explores its prospective in clinical practices and scientific researches in the field. Related Articles | Metrics

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Research progress on cementoblast WU Wei-feng, GUO Shu-juan, WU Ya-fei. Inter J Stomatol. 2011, 38 (1):  95-97.  DOI: 10.3969/j.issn.1673-5749.2011.01.026 Abstract ( 1192 )   HTML ( 11 )   PDF（pc） (110KB) ( 907 )   Save Cementum regeneration plays an important role in periodontal tissue regeneration. This paper reviewed the scholarly cementoblast cell researches, explained the source and function of cementoblasts, the influence of bone morphogenetic protein, enamel matrix derivative, cementum protein-1, and dentin non-collagen protein on cementoblasts cell proliferation, differentiation and mineralization. Related Articles | Metrics

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Research progress on pluripotency regulation by Oct4 and its isoforms KONG Qian-ying, WEI Xi. Inter J Stomatol. 2011, 38 (1):  98-101.  DOI: 10.3969/j.issn.1673-5749.2011.01.027 Abstract ( 982 )   HTML ( 2 )   PDF（pc） (143KB) ( 760 )   Save Reprogramming of somatic cells to embryonic stem cell（ESC）-like induced pluripotent stem cells has been achieved by transfection of the four transcriptions factors（oct4, sox2, c-Myc and klf4）. Oct4 is indispensable for reprogramming, and plays important roles in transcriptional regulation, signal transduction, epigenetic modification and so on. By reviewing how Oct4 and its isoforms contribute to pluripotency maintenance in ESC, we show how Oct4 works in pluripotency regulation of cellular reprogramming. Meanwhile, this will help to provide rationale for the researches on stemness regulation by Oct4 in dental pulp stem cell. Related Articles | Metrics

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Current status of transport distraction osteogenesis for the reconstruction of craniomaxillofacial skeletal defect SONG Ji-chuan, ZHOU Nuo. Inter J Stomatol. 2011, 38 (1):  102-105.  DOI: 10.3969/j.issn.1673-5749.2011.01.028 Abstract ( 995 )   HTML ( 2 )   PDF（pc） (127KB) ( 607 )   Save Transport distraction osteogenesis has been an extremely effective surgical technique for reconstructing critical-size skeletal defects of human long bones. It can also be applied efficiently in the reconstruction of extensive defects of craniomaxillofacial bones, which are caused by trauma, tumour resection, osteomyelitis, and bony nonunion and so on. This study reviewed its application in the craniomaxillofacial skeletal reconstruction. Related Articles | Metrics

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Research progress on CA125 as a tumor marker GENG Xue-fei, XING Ru-dong. Inter J Stomatol. 2011, 38 (1):  106-108.  DOI: 10.3969/j.issn.1673-5749.2011.01.029 Abstract ( 1264 )   HTML ( 4 )   PDF（pc） (108KB) ( 757 )   Save CA125 antigen was detected in 1981. Studies have found that the level of CA125 in the healthy people and benign tumor sufferers is low, but high in malignant tumor sufferers, especially when the tumor grows very fast. This article will summarize the CA125 contents in all kinds of malignant tumor sufferers and discuss the relationships between CA125 levels and the existence of tumor, clinical stage and prognosis, especially concentrating on the studies of CA125 levels and oral cancer. Related Articles | Metrics

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Research progress on periodontal conditions in subjects following orthodontic therapy ZHOU Hang, CAI Ping. Inter J Stomatol. 2011, 38 (1):  109-111.  DOI: 10.3969/j.issn.1673-5749.2011.01.030 Abstract ( 1044 )   HTML ( 7 )   PDF（pc） (105KB) ( 729 )   Save Although orthodontic treatment brings some harmful effects, the therapeutic effect is affirmative. The adverse effect of orthodontic treatment on periodontal tissues is one of the problems which often baffles clinicians. Many factors can influence periodontal conditions, such as orthodontic force, orthodontic attachments and oral hygiene. This article is to review the total reference of malocclusion and orthodontic treatment with periodontal disease, and the effects of orthodontic treatment on gingival hyperplasia, gingival recession, loss of adhesion, root resorption and to contribute to clinical work. Related Articles | Metrics

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Methods of measuring tooth mobility LI Lei-dan, LI Chao-lun. Inter J Stomatol. 2011, 38 (1):  112-114.  DOI: 10.3969/j.issn.1673-5749.2011.01.031 Abstract ( 1933 )   HTML ( 4 )   PDF（pc） (106KB) ( 2015 )   Save Tooth mobility refers to the movement degree of natural teeth or implants in the force, which can evaluate the situation of teeth supporting tissues, for the treatment as an important indicator of prognosis. Dentists usually measure tooth mobility with denting forceps in clinic, which mostly depends on experience. To avoid such error, a lot of instruments have been invented. This article will introduce some of them to review the achievement and advancement in this field． Related Articles | Metrics

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Review on the factors affecting torque expression in orthodontic treatment JIANG Chun-miao, AN Shu, WANG Jun. Inter J Stomatol. 2011, 38 (1):  115-118.  DOI: 10.3969/j.issn.1673-5749.2011.01.032 Abstract ( 2094 )   HTML ( 19 )   PDF（pc） (132KB) ( 3152 )   Save Proper buccolingual inclination of teeth is essential to esthetics, stability and occlusion in orthodontic treatment. Factors influencing torque in various orthodontic treatments are frequently discussed by clinical orthodontists. Good control of torque can get the normal buccolingual inclination and beautiful curve of the teeth. Clinically, there are many factors affecting the tooth torque control, such as labial surface shape of crown, root-tooth angle, tip and the center height of clinical crown. Besides, preset angle of brackets, adhesive height, texture of the arch wires, and so on, also have effects. In this paper, we will give a comprehensive review on the factors affecting torque expression in three aspects: Anatomical factors of the tooth, brackets and the properties of the archwire, respectively. Related Articles | Metrics

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Study of relationship between expression of CC chemokine receptor 7 and its ligands and oral squamous cell carcinoma JIN Xin, WANG Jing, WANG Fang, ZENG Xin, CHEN Qian-ming. Inter J Stomatol. 2011, 38 (1):  119-121.  DOI: 10.3969/j.issn.1673-5749.2011.01.033 Abstract ( 1017 )   HTML ( 3 )   PDF（pc） (116KB) ( 649 )   Save Chemokines belong to the small molecule chemoattractive cytokine family. They are involved in diverse biological actions through combining with their specific receptors. Recent studies showed that the expression of CC chemokine receptor 7（CCR7） were significantly associated with the invasion and lymph node metastasis of oral squamous cell carcinoma（OSCC）. This review will concentrate on the functions of CCR7 and its ligands, and their effects in invasion and lymph node metastasis of OSCC. Related Articles | Metrics