Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (1): 63-66.doi: 10.3969/j.issn.1673-5749.2011.01.018

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Research progress on chromosome gene locus on the nonsyndromic cleft lip with or without cleft palate

ZHUGE Xu-qing, ZHENG Qian.   

  1. Dept. of Cleft Lip and Palate Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2009-10-04 Revised:2010-06-07 Online:2011-01-20 Published:2011-01-20

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Abstract:

Cleft lip with or without cleft palate（CL/P） is one of the most common congenital deformity which is considered as a combination factors of genetic and environment. More risked genes have been found under the great development of the molecular genetics. This context is a review on the novest CL/P-linked research about the locus of the risk candidate genes on the chromosomes.

Key words: nonsyndromic cleft lip with or without cleft palate, chromosome, gene locus


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