Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (1): 51-54.doi: 10.3969/j.issn.1673-5749.2011.01.015

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Research progress on secreted aspartyl proteinase -2

LIN Yan, ZHAO Wei.   

  1. Dept. of Pediatric Dentistry, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou 510055, China; Research Institute of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou 510055, China
  • Received:2009-09-15 Revised:2010-06-01 Online:2011-01-20 Published:2011-01-20

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Abstract:

The secreted aspartyl proteinase（Sap）-2 is required for growth of the fungus and is a virulence factor. Moreover, Sap-2 is known to induce antibody response during Saccharomyces albicans infection. Sap-2 is involved in many aspects of pathogenic process. The origin, structure, biological characteristics, expression, influence factors, the mechanism of pathogenicity and application will be reviewed in this paper.

Key words: secreted aspartyl proteinase-2, virulence factor, Saccharomyces albicans


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