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20 May 2009, Volume 36 Issue 3 Previous Issue    Next Issue

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Anesthesia management for radioactive seed implantation in treatment of oral and YANG Xu-dong, DONG Wen, ZHANG Jian-guo Inter J Stomatol. 2009, 36 (3):  253-255，259.  DOI: 10.3969/j.issn.1673-5749.2009.03.001 Abstract ( 1843 )   HTML ( 6 )   PDF（pc） (156KB) ( 800 )   Save Objective To investigate characteristics of anesthesia management for radioactive seed implantation in treatment of oral and maxillofacial malignant tumor. Methods 76 patients with oral and maxillofacial malignant tumor receiving treatment of radioactive seed implantation were given three types of anesthesia according to indications: Local anesthesia plus intravenous sedation（group LA）, general anesthesia with endotracheal intubation（group TT） and general anesthesia with laryngeal mask airway（group LMA）. Changes of patients′ blood pressure（BP）, heart rate（HR） and saturation of pulse oxygen（SpO2） during operation were recorded. Characteristics of anesthesia induction and maintenance and perioperative complications were observed. Results Among the 76 patients, 12 patients were enrolled into group LA, 24 patients were enrolled into group TT and 40 patients were enrolled into group LMA. Perioperative cardiovascular response in group LA was more intense than that in group TT and group LMA（P<0.05）. The lowest SpO2 during operation of group LA was lower than preoperative value and than that of group TT and group LMA（P<0.05）. Patients in group LA had more body movements and more pain than that in group TT and group LMA（P<0.05）. One patient of group LA had hypoxemia during operation. In group TT, 9 patients had difficult intubation and the successful rate of first insertion was 62.5%. One patient of group TT received emergency tracheotomy because of postoperative airway obstruction. The successful rate of first insertion in group LMA was 90%. There was no difference between group TT and group LMA with respect to cardiovascular change and lowest SpO2. 9 patients of group LMA showed leakage during operation but no hypoxemia occurred. Conclusion In maxillofacial radioactive seed implantation surgery, different anesthesia methods should be chosen according to indications. Local anesthesia plus intravenous sedation is not likely to produce perfect analgesia, while general anesthesia with endotracheal intubation may have difficult intubation. Laryngeal airway mask is easy to insert and can be used under safety and feasibility in such operations. Related Articles | Metrics

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Clinical evaluation of dentine sensitivity after scaling and root planing GONG Yi-ming, DING Xiao-jun, REN Ying Inter J Stomatol. 2009, 36 (3):  256-259.  DOI: 10.3969/j.issn.1673-5749.2009.03.002 Abstract ( 2432 )   HTML ( 6 )   PDF（pc） (191KB) ( 922 )   Save Objective To evaluate the prevalence and intensity of dentine sensitivity（DS） after scaling and root planing. Methods The study was carried out with 38 subjects who had chronic periodontitis requiring for scaling and root planing. DS was scored by the subjects on a 0-10 visual analogue scale（VAS） after cold air stimulation of the test teeth at baseline and 5 minutes after the treatment, 1 week after the treatment and 4 weeks after the treatment. The prevalence and intensity of DS was compared between the baseline and post -treatment. Results There was a significant increase in the prevalence of DS after 1 week after the treatment（52.6%） compared to baseline data（28.9%, P<0.05）. The VAS of sensitive teeth 1 week after the treatment（4.1±1.7） was also significantly higher than that at baseline（2.9±1.7, P<0.05）. The prevalence and intensity of DS showed statistical decrease 4 weeks after the treatment, no significant difference was found compared with baseline（P>0.05）. Conclusion Scaling and root planing may play a role in the etiology of dentine sensitivity. Related Articles | Metrics

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The diagnosis and treatment of basal cell naevus syndrome WANG Yin , GUO Jing-jie, YANG Jun, SUN Geng-lin, LI Long-jiang Inter J Stomatol. 2009, 36 (3):  260-262.  DOI: 10.3969/j.issn.1673-5749.2009.03.003 Abstract ( 2870 )   HTML ( 4 )   PDF（pc） (196KB) ( 840 )   Save Objective The purpose of this study was to evaluate the clinical manifestation, diagnosis and treatment of basal cell naevus syndrome（BCNS）. Methods Reviewed the procedure of diagnosis and treatment by analyzing the records of 4 inpatients of BCNS in General Hospital Affiliated to Tianjin Medical University from 1999 to 2007. Results The inpatients characterized with typical facial features, cutaneous basal cell naevus（carcinoma） were obviously seen on the skin, palmar or plantar pits were viewed, bilamellar calcification of falx cerebri, bifid, fused or markedly splayed ribs were found, and histologically confirmed odontogenic keratocysts of jaw could be detected in most cases of BCNS. No family history was found in all cases of the group. Conclusion Multiple odontogenic keratocysts of jaw is one of the most important clinical manifestation of BCNS. The correct and prompt treatment will provide the patients with better life quality. Related Articles | Metrics

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Dentoskeletal and soft tissue profile changes after maxillary YE Jin-mei, DENG Li-qin, ZHAI Jia-yu, JIANG Jie, WANG Hong-tao, DENG Xi-he Inter J Stomatol. 2009, 36 (3):  263-266.  DOI: 10.3969/j.issn.1673-5749.2009.03.004 Abstract ( 1578 )   HTML ( 7 )   PDF（pc） (223KB) ( 808 )   Save Objective To evaluate the changes of dentoskeletal and soft tissue profile of the patients with skeletal class Ⅲ after maxillary protraction with rapid expansion in the primary class Ⅲ dentition. Methods Eight patients with serious skeletal class Ⅲ, 5 males and 3 females, in the primary dentition were selected. The patients present with a concave facial profile, anterior or posterior crossbite. No apparent mandibular displacement was found in all patients. Cephalograms were taken before and after maxillary protraction with expansion. Results The maxillary was protracted significantly, whereas the mandible was positioned backward significantly, with a concomitant decrease in the skeletal facial angle. The corresponding soft tissue changes displayed significant decrease in soft tissue facial angle, the skeletal and soft tissue profile showed similar increases in lower facial height. The maxillary incisors tipped labially, while the mandibular incisors tipped lingually. Lip structure changed with increased upper lip convesity and decreased lower lip convexity, the inclination of the upper and the lower lip decrease significantly. Conclusion This treatment shows that significant dentoskeletal and soft tissue changes and improvements in dentofacial profile result from 6 months of treatment with maxillary expansion and protraction. Related Articles | Metrics

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Clinical evaluation of rotary ProTaper in preparation of root canal during retrea LI Yan, ZHAO Jin, SUN Yu-liang, NIU Qiao-li Inter J Stomatol. 2009, 36 (3):  267-269.  DOI: 10.3969/j.issn.1673-5749.2009.03.005 Abstract ( 1840 )   HTML ( 10 )   PDF（pc） (114KB) ( 1402 )   Save Objective To assess the clinical effect of rotary ProTaper in preparation of root canal during retreatment. Methods A total of 120 teeth which needed endodontic retreatmemt were selected and randomly divided into 2 groups with 60 teeth in each group. The root canals were prepared with rotary ProTaper and crown-down technique in experimental group（PT） and K-files with step-back technique in control group（HF）, respectively. And both filled with cold lateral condensation technique. To record the prepared time and numbers of postoperative complications, and according to X-ray of pre-therapy and post-therapy to estimate the effect of root canal preparation and filling. Results The time of preparation in PT group was obviously shorter than HF group. The effect of root canal shaping and filling in PT group was better than that in HF group. There were 3 fractured instruments in PT group. Conclusion Rotary ProTaper showed high performance, better shaping ability and effective obturation, but we should pay attention to prevent instrumental fracture. Related Articles | Metrics

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Effect on incidence of cleft palate interfered by different do HE Wei , LU Sheng -jun , LI Cheng -hao , MENG Tian , ZHOU Jing -lin , SHI Bing Inter J Stomatol. 2009, 36 (3):  270-272.  DOI: 10.3969/j.issn.1673-5749.2009.03.006 Abstract ( 1873 )   HTML ( 7 )   PDF（pc） (120KB) ( 1262 )   Save Objective To define the optimal dose of dexamethasone induced cleft palate in C57BL/6J mice and to provide a reliable model of cleft palate for further study. Methods Pregenant mice at specific period were divided into five groups randomly, that were control group and experimental groups of Ⅰ, Ⅱ, Ⅲ, Ⅳ. The mice of the control group were injected sodium chloride 0.1 mL and the mice of experimental Ⅰ, Ⅱ, Ⅲ, Ⅳ groups were injected dexamethasone of 12.0, 6.0, 3.2, 1.6 mg/kg respectively at 8:00 am on embryo 10 to embryo 12. To weigh pregnant mice and embryos and record the number of embryonic resorption and cleft palate after pregnant mice were killed on embryo 17.5. Results Weight of pregnant mice was significantly different（P<0.05）, but the number of embryonic resorption and cleft palate had no significant difference between control group and experimental Ⅲ, Ⅳ groups（P > 0.05）. Incidence of embryonic cleft palate had significant difference between control group and experimentalⅠ,Ⅱgroups（P<0.05）. However, incidence of embryonic resorption increased significantly in experimental Ⅰgroup（P<0.05）. There was no difference in embryonic weight among each group（P>0.05）. Conclusion 6.0 mg/kg is the optimal dose of dexamethasone to induce cleft palate in C57BL/6J mice. Related Articles | Metrics

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Dental age assessment using Demirjian′s method on Chengdu children aged from eig CHEN Jian-wei, LIU Ze-ping, GUO Jing, LIU Ren-kai, CHEN Ting-ting, ZOU Shu-juan Inter J Stomatol. 2009, 36 (3):  273-275.  DOI: 10.3969/j.issn.1673-5749.2009.03.007 Abstract ( 1644 )   HTML ( 5 )   PDF（pc） (118KB) ( 751 )   Save Objective To evaluate the applicability of Demirjian′s method for dental age estimation in Chengdu children, aged from 8 to 16, and to modify it if needed. Methods Demirjian′s method was used to assess the dental maturity score and dental age of 445 Chengdu children. The differences between dental age and chronological age were compared using paired t -test. The nonlinear regression method was used to establish the logistic model between the dental maturity scores and chronological age. Results The mean differences between dental age and chronological age were 0.67 years in female and 0.52 years in male. The logistic model of the dental maturity scores and chronological age was an exponential model. Conclusion Demirjian's method need to be modified to be used in dental age assessment of Chengdu children. Related Articles | Metrics

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Evaluation about the effects of non -extraction treatment for patients of differe ZAN Lin, LIN Bao-shan, DENG Xiao, CHEN Song Inter J Stomatol. 2009, 36 (3):  276-280.  DOI: 10.3969/j.issn.1673-5749.2009.03.008 Abstract ( 1675 )   HTML ( 6 )   PDF（pc） (181KB) ( 928 )   Save Objective To evaluate the optimal time for fixed appliance treatment and the relation between orthodontic treatment and growth of Angle class Ⅱ division 1 malocclusion during growth periods. Methods 60 patients with Angle class Ⅱ division 1 malocclusion were selected according to the cervical vertebral maturation （CVM） method for the assessment of mandibular growth made by Baccetti, including non-extraction group and control group in the growth peak, and non-extraction group and control group after growth peak. The number of male and female in each group was the same. All the lateral cephalometric photos before and after treatment were analyzed. Results Soft and hard tissues had been changed after treatment. The bone effect of non -extraction group in the growth peak after treatment was better than the non-extraction group after the growth peak（P＜0.05）, but no statistically significant difference was found in most parts of teeth and soft tissues between the two groups （P＞0.05）. Conclusion The development of maxilla is restrained and the growth of mandible and chin is stimulated after non-extraction treatment of Angle class Ⅱ division 1 malocclusion during growth period. In order to get a better bone effect, treatment should be given as early as possible in the growth peak. Related Articles | Metrics

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Changes of hard tissues of patients with Angle class Ⅱ division 1 malocclusion b NA Bin, BAI Xue-qin, LIU Xue-heng Inter J Stomatol. 2009, 36 (3):  281-284.  DOI: 10.3969/j.issn.1673-5749.2009.03.009 Abstract ( 1450 )   HTML ( 6 )   PDF（pc） (138KB) ( 1059 )   Save Objective The study was to investigate the changes of hard tissues of patients with Angle class Ⅱ division 1 malocclusion by Damon-Ⅲ and MBT technique. Methods The sample consisted 20 patients with Angle class Ⅱ division 1 malocclusion by MBT technique and 20 patients with Angle class Ⅱ division 1 malocclusion by Damon-Ⅲ technique. All of them were extracted all the first premolars and without any other anchorage appliances added. The pre- and after-treatment cephalometric films were measured to assess the treatment effect. Results After treatment, the maxilla and mandible in two groups did not change significantly in sagittal direction, but had the trend to increase in vertical. The dental measurement were changed but had a little bit of difference between two groups. Conclusion Good results could be obtained in patients with Angle class Ⅱ division 1 malocclusion by using Damon-Ⅲ and MBT technique. Anchorage could be controlled successfully in two groups. But the anterior tooth torque control is dissatisfactory in Damon-Ⅲ technique group. Related Articles | Metrics

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The clinical analysis of 2×4 corrective technique applied in correcting the ante CUI Zhou-ying, LAI Wen-li, JIANG Xing-ke, ZHANG Ying-min Inter J Stomatol. 2009, 36 (3):  285-287.  DOI: 10.3969/j.issn.1673-5749.2009.03.010 Abstract ( 1511 )   HTML ( 5 )   PDF（pc） (165KB) ( 1245 )   Save Objective To discuss the clinical effects and characteristics of 2×4 corrective technique applied in correcting the anterior crossbite during the mixed dentition. Methods The 2×4 corrective technique and biteplate of posterior upper teeth as well as Class Ⅲ elastic force was applied to correct the anterior crossbite of mixed dentition. Results This method was able to correct the anterior crossbite and also to reduce the time of treatment and to spare the frequency of seeing the doctor again. Conclusion 2 ×4 corrective technique is an effective method of correcting the anterior crossbite during the mixed dentition and is valuable to spread. Related Articles | Metrics

Case Report

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Root canal therapy for taurodontism： A case report and literature review SHAO Mei -ying, ZHENG Guang -ning, HU Tao Inter J Stomatol. 2009, 36 (3):  288-290.  DOI: 10.3969/j.issn.1673-5749.2009.03.011 Abstract ( 2481 )   HTML ( 10 )   PDF（pc） (211KB) ( 1051 )   Save Taurodontism is characterized by larger pulp champer, decreased root length and less marked cervical constriction. It has also been associated with several syndromes and anomalies, however, it most frequently appears as an isolated anomaly. A failure of Hertwig′s epithelial root sheath to invaginate at the appropriate horizontal level shed important light on the pathogenesis of taurodontism. To date, the etiopathogenesis of taurodontism is unclear. When these teeth are infected by endodontitis or apical periodontitis, root canal therapy is still the best choice. One case of taurodontism was reported and relevant literatures were reviewed. The possible etiology and treatment of taurodontism was discussed. Related Articles | Metrics

Reviews

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Effects of the chitosan and its derivatives on the cariogenic bacteria JING Jun-jun, HAO Yu-qing Inter J Stomatol. 2009, 36 (3):  291-293.  DOI: 10.3969/j.issn.1673-5749.2009.03.012 Abstract ( 1626 )   HTML ( 4 )   PDF（pc） (112KB) ( 1122 )   Save Chitosan is a unique degradable polymer of biological activity. The recent study found that chitosan had a variety of physiological effects, in particular, having a good antibacterial activity. This article summarized its effects on the growth of bacteria, the adhesion of bacteria and the plaque pH value, also the affecting factors of its antibacterial activity. Related Articles | Metrics

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Research progress on migration of dental pulp cells YANG Hui, HU Tao Inter J Stomatol. 2009, 36 (3):  294-296.  DOI: 10.3969/j.issn.1673-5749.2009.03.013 Abstract ( 1359 )   HTML ( 5 )   PDF（pc） (112KB) ( 969 )   Save Defensive reaction is initiated when the pulp is suffered from potential harmful stimulus. Secreting or releasing cytokines constructs a complex regulatory network to activate certain signaling pathways, resulting in reparative dentin formation to protect the pulp from noxious stimulus. The directional migration of dental pulp cells to the injured sites is pivotal to the regeneration process. This review focused on the research progress in migration of dental pulp cells. Related Articles | Metrics

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Research progress and assessment of laser fluorescence method for early caries de LI Xiao -lan, LING Jun-qi Inter J Stomatol. 2009, 36 (3):  297-299，302.  DOI: 10.3969/j.issn.1673-5749.2009.03.014 Abstract ( 1446 )   HTML ( 4 )   PDF（pc） (132KB) ( 675 )   Save Dental caries is a progressive disease and deficiency in which multiple factors coactivate to hard tissue of the tooth. It reflects as demineralization of calcified tissue and disintergration of organic material, and progresses from color-changing to substantial cavity. The detection of early caries is a key element in the prevention and treatment of dental caries. Laser fluorescence is a new diagnostic tool to detect and quantify caries based on the principle that carious dental tissues emit higher fluorescence than sound tissue. With its higher sensitivity, accuracy and reliability than conventional diagnostic methods and non-invasive technique, laser fluorescence is considered to be an effective adjunct tool for early caries detection. This article intended to review its principle, diagnostic value, clinical application and influencing factors. Related Articles | Metrics

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Present study of physiologic root resorption in primary teeth WANG Jiao-cui, ZHAO Wei Inter J Stomatol. 2009, 36 (3):  300-302.  DOI: 10.3969/j.issn.1673-5749.2009.03.015 Abstract ( 1697 )   HTML ( 5 )   PDF（pc） (114KB) ( 1277 )   Save Primary root resorption is a physiological event for the primary teeth and plays an important role during normal replacement procedure． The structure and functions of odontoclast during primary root resorption and the related enzymes were summarized in this article． Related Articles | Metrics

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The role of core binding factor α1 in periodontal tissue during the orthodontic HE Qi, CHEN Dan-peng, PAN Jin-song Inter J Stomatol. 2009, 36 (3):  303-306.  DOI: 10.3969/j.issn.1673-5749.2009.03.016 Abstract ( 1522 )   HTML ( 3 )   PDF（pc） (150KB) ( 921 )   Save Core binding factor α1（Cbfα1） has been identified as a key regulator of osteoblast differentiation and bone formation, a osteoblast-specific ranscription factor in osteoblast genesis and differentiation. Cbfα1 participates in the tissues remodeling during orthodontic tooth movement and plays an important role in the remodeling of periodontal tissue． Related Articles | Metrics

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Reconsideration of calcium hydroxide as an intracanal medication ZHONG Su-lan, YIN Shi-hai Inter J Stomatol. 2009, 36 (3):  307-309.  DOI: 10.3969/j.issn.1673-5749.2009.03.017 Abstract ( 1820 )   HTML ( 18 )   PDF（pc） (112KB) ( 2936 )   Save Calcium hydroxide（CH） is used mostly as an intracanal medication in clinical situations. The disinfection of CH has been widely acknowledged. However, the current studies show that CH is not effective against for all bacteria, especially the root canal flora of refractory apical periodontitis, the antibacterial efficacy is not expected. The medicaments and clinical operation may influence the antibacterial efficacy. Related Articles | Metrics

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Photo-activated disinfection and its application in the treatment of root canal i QI Yi-pin, LING Jun -qi Inter J Stomatol. 2009, 36 (3):  310-312.  DOI: 10.3969/j.issn.1673-5749.2009.03.018 Abstract ( 1824 )   HTML ( 4 )   PDF（pc） (108KB) ( 729 )   Save Photo-activated disinfection（PAD）, also known as photodynamic therapy or light-activated antimicrobial chemo-therapy, involves the use of a photoactive dye（photosensitizer） that is activated by exposure to light of a specific wavelength in the presence of oxygen. It is endowed with several favorable features for the treatment of infection in root canals, including a broad spectrum of antibacterial effect, the localization of its action, and the efficient inactivation of antibiotic-resistant strains. PAD provides an alternative approach to controlling root canal infection. This review summarized the mechanism of PAD and researches on its application in the inactivation of root canal bacteria. Related Articles | Metrics

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Advancement of cell adhesion molecules in periodontal diseases MAO Xue -li, LING Jun -qi Inter J Stomatol. 2009, 36 (3):  313-315.  DOI: 10.3969/j.issn.1673-5749.2009.03.019 Abstract ( 1621 )   HTML ( 3 )   PDF（pc） (108KB) ( 871 )   Save Different populations of cells are involved in the activity of inflammatory and immune responses. Cell adhesion molecules are proteins which locate on cell surface or in the surrounding of cell and mediate the contact of cell-cell or cell-matrix. In this review we summarized the structure, distribution, and function of cell adhesion molecules involved in the periodontal diseases. Related Articles | Metrics

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Clinical research model of the psychosocial factors contributing to periodontal d LI Quan, XU Chun-jiao Inter J Stomatol. 2009, 36 (3):  316-318.  DOI: 10.3969/j.issn.1673-5749.2009.03.020 Abstract ( 1496 )   HTML ( 4 )   PDF（pc） (106KB) ( 894 )   Save Along with the transformation of medical pattern from the traditional biomedical model to the biopsychosocial medical model, social psychic factors may contribute to the onset, progress, treatment and prognosis of the periodontal disease. Based on the latest clinical studies of the relationship between psychosocial factors and periodontal disease, psychological measurements, characteristics of the periodontal outcome measures, research design and the statistical analysis and control of the confounding factors were concretely demonstrated in this review, which made it convenient to further explore the etiological relationship between the psychosocial factors and the periodontal disease in clinical study. Related Articles | Metrics

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Roles of 4-1BB and 4-1BB ligand in oral cancer immunotherapy SUN Shun-tao, YANG Hong-yu Inter J Stomatol. 2009, 36 (3):  319-322.  DOI: 10.3969/j.issn.1673-5749.2009.03.021 Abstract ( 1352 )   HTML ( 3 )   PDF（pc） (140KB) ( 747 )   Save 4-1BB and 4-1BB ligand（4-1BBL） are members of the tumor necrosis factor/tumor necrosis factor receptor family, which are expressed on T cells and antigen-presenting cells （APC） respectively. In recent study, therapies utilizing the 4-1BB/4-1BBL signaling pathway have been shown to have antitumor effects in a number of model systems. In this report, we focus solely on the role of 4-1BB and its receptor 4-1BBL in costimulation and discuss its potential as a target for the immunotherapy of oral cancer. Related Articles | Metrics

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Research progress on the role of environmental factors in the etiology of non-Hod LI Xin, LI Long-jiang Inter J Stomatol. 2009, 36 (3):  323-325.  DOI: 10.3969/j.issn.1673-5749.2009.03.022 Abstract ( 1435 )   HTML ( 3 )   PDF（pc） (106KB) ( 1035 )   Save The last thirty years saw a rise in the incidence of non-Hodgkin lymphoma, and it is now one of the most common neoplasms. Lymphomagenesis is a complex process and that many of the pathologic subtypes of lymphoma have different etiologies. Thus, the study of environmental factors becomes more and more important. This paper reviewed the research advance on the role of environmental factors in the etiology of non-Hodgkin lymphoma. Related Articles | Metrics

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Matrix extracelluar phosphoglycoprotein and its important fragments ZHOU Xiao-yan, WEI Xi Inter J Stomatol. 2009, 36 (3):  326-328，331.  DOI: 10.3969/j.issn.1673-5749.2009.03.023 Abstract ( 1607 )   HTML ( 4 )   PDF（pc） (143KB) ( 759 )   Save Matrix extracelluar phosphoglycoprotein（MEPE）, which is one of the matrix extracelluar non-collagenous proteins, is expressed in bone, teeth and renal proximal convoluted tubules. It is considered to be a potential phosphatonin. And it plays an important role in bone formation and mineralization. ARASM fragments and dentonin/AC-100, motifs derived from MEPE, are the focus of recent research. Related Articles | Metrics

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The correlation of cyclophilin A with oral squamous cell cancer MA Lan, SHEN Shi-qian, WANG Zhen, ZHANG Wei-wei, CAO Zheng-guo Inter J Stomatol. 2009, 36 (3):  329-331.  DOI: 10.3969/j.issn.1673-5749.2009.03.024 Abstract ( 1759 )   HTML ( 3 )   PDF（pc） (108KB) ( 1033 )   Save Cyclophilin A is a group of highly conserved proteins and it generally presents in many kinds of cells. Cyclophilin A has many biological functions and plays an important role in the pathophysiologic process. Cyclophilin A could participate in the tumorgenesis, invasion, cell proliferation, vascular growth of oral squamous cell carcinoma, which was reviewed in the paper. Related Articles | Metrics

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Research progress of emdogain in the field of stomatology ZHANG Li-juan, ZHAO Shi-fang Inter J Stomatol. 2009, 36 (3):  332-334.  DOI: 10.3969/j.issn.1673-5749.2009.03.025 Abstract ( 1596 )   HTML ( 4 )   PDF（pc） (109KB) ( 1072 )   Save Emdogain is the conjugate of enamel matrix derivative and corresponding carrier, which can promote regeneration of periodontal tissues, biomineralization, bone induction and so on. Many researchers reached some results in emdogain from culture in vitro, animal studies and clinic trials. This review summarized emdongain and its role in periodontal disease, maxillofacial defects, dental implantation and so on. Related Articles | Metrics

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Mechanism of bone morphogenetic protein/Smad singaling pathway and its response t CHENG Zong-sheng, GUAN Jian Inter J Stomatol. 2009, 36 (3):  335-337.  DOI: 10.3969/j.issn.1673-5749.2009.03.026 Abstract ( 1654 )   HTML ( 4 )   PDF（pc） (118KB) ( 644 )   Save Bone morphogenetic protein（BMP）, one of multifunctional secreted signaling molecules, is a member of the transforming growth factor-β superfamily. BMP regulates a wide spectrum of cellular functions such as proliferation, differentiation, migration and apoptosis, and also plays central roles in morphogenesis of various organs, embryonic development as well as reparation of injured tissues. Smad（sma-mad） protein is intracellular signaling transduction and regulatory molecules of BMP. Signal transduction studies have revealed that Smad can transduce the BMP signal from the cellmembrane to the nucleus, forming the BMP/Smad singaling pathway. Recently, researches have show that BMP/Smad singaling pathway regulates bone formation in distraction osteogenesis（DO）. Indepth understanding of osteoblast BMP/Smad signaling pathway to stimulate the mechanical response mechanisms and the role of molecular biology DO mechanism for the application of exogenous BMP and provide a theoretical basis for gene therapy. Related Articles | Metrics

综述

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Relationship between high temperature requirement A and dental caries caused by < LI Jing, LIU Xing-rong Inter J Stomatol. 2009, 36 (3):  338-338～340.  Abstract ( 1601 )   HTML ( 2 )   PDF（pc） (119KB) ( 1059 )   Save Streptococcus mutans（S.mutans） is known as a primary pathogen of dental caries, and its exopolysaccharide synthesis, adherence to tooth surface and biofilm formation is important physiological and virulence factor of S.mutans. High temperature requirement A（HtrA） is a periplasmic heat shock protein, which reduces the ability to withstand high temperature, extreme of pH and oxidative stress. This article reviewed the relationship between HtrA and virulence factors of S.mutans. Related Articles | Metrics

Reviews

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Crosstalk between Wnt and Notch signaling pathways and their relationships with o PANG Bao -xing, JIN Xiao -ming Inter J Stomatol. 2009, 36 (3):  341-343.  DOI: 10.3969/j.issn.1673-5749.2009.03.028 Abstract ( 1314 )   HTML ( 3 )   PDF（pc） (118KB) ( 1555 )   Save Wnt and Notch signaling pathways have long been regarded as the signaling pathways playing critical roles in the tumorigenesis and progression of various kinds of human cancers. This article reviewed the crosstalk between Wnt and Notch signaling pathways, particularly focusing on their relationship with oral squamous cell carcinoma. Related Articles | Metrics

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Research progress of cyclo-oxygenase-2 selective inhibitor Celecoxib and the inva HUO Qiu-ju, LI Wei-zhong Inter J Stomatol. 2009, 36 (3):  344-346，350.  DOI: 10.3969/j.issn.1673-5749.2009.03.029 Abstract ( 1493 )   HTML ( 2 )   PDF（pc） (141KB) ( 707 )   Save Cyclo-oxygenase（COX） is the major rate-limiting enzyme for the synthesis of prostaglandins. COX-2, which is the inducible form, involved in inflammation and cancer incidence. Study found, COX-2 was overexpressed in the majority of malignant carcinomas including tongue squamous carcinoma. In addition, the increasing activity of COX-2 can improve the adhesion capacity of cells and the extracellular matrix protein, enhance expression level of matrix etalloprotease, and increase the invasion of tumor cells. Further studing the relationship between the cyclo -oxygenase -2 selective inhibitor and tongue squamous carcinoma invasion is very important for tongue cancer treatment and prognosis. Related Articles | Metrics

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Research progress of finite element analysis on fatigue behavior o f all -ceramic HUANG Jue-hui, ZHAO Ke, ZHANG Xin-ping Inter J Stomatol. 2009, 36 (3):  347-350.  DOI: 10.3969/j.issn.1673-5749.2009.03.030 Abstract ( 1322 )   HTML ( 2 )   PDF（pc） (133KB) ( 692 )   Save All-ceramic crowns and bridges have been widely used for dental restorations owing to their excellent functionality, aesthetics and biocompatibility. However, the premature clinical failure of all -ceramic crowns and bridges may easily occur when subjected to repetitive occlusal contact loading. In order to provide efficient theoretical instruction for clinical applications, the finite element method can be used to analyze the fatigue behavior, optimize the design of all-ceramic crowns and bridges, and to evaluate the reliability and durability. This paper reviewed the recent research progress of fatigue behavior of all -ceramic crowns and bridges by finite element method. Related Articles | Metrics

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Regulation of receptor activator of nuclear factor-κB ligand-receptor activator LIU Li, LUO Yun, WANG Min Inter J Stomatol. 2009, 36 (3):  351-354.  DOI: 10.3969/j.issn.1673-5749.2009.03.031 Abstract ( 1496 )   HTML ( 3 )   PDF（pc） (147KB) ( 1014 )   Save Receptor activator of nuclear factor-κB ligand（RANKL）-receptor activator of nuclear factor-κB（RANK）and osteoprotegerin（OPG） discovered in the mid 1990s is the key signaling system for the regulation of bone resorption. RANKL-RANK signaling regulates osteoclast formation, activation and survival in normal bone modeling and remodeling and increases bone resorption in a variety of pathologic conditions. OPG protects bone from excessive resorption by binding to RANKL and preventing it from binding to RANK. This article reviewed regulation of RANKL-RANK-OPG in bone modeling and remodeling. Related Articles | Metrics

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Clinical research about cracked tooth CHEN Yu, LIN Zheng-mei Inter J Stomatol. 2009, 36 (3):  355-357，360.  DOI: 10.3969/j.issn.1673-5749.2009.03.032 Abstract ( 1593 )   HTML ( 33 )   PDF（pc） (135KB) ( 2106 )   Save Epidemiological data reveals that as the improving of the oral health, morbidity rate of caries and periodontal diseases has decreased. Tooth fracture becomes a common cause of tooth loss in industrialized countries. Cracks and fractures can be classified as follows due to the extension and tissue involved: craze lines, fractured cusps, cracked teeth, split teeth and vertical root fractures. According to the pulp status and cracked extension, tooth fracture falls into two different types, which are incomplete tooth fracture and complete tooth fracture of vital and non-vital tooth. Cracked tooth belongs to the incomplete tooth fracture of tooth with vital pulp. The cracked tooth with symptoms is called cracked tooth syndrome. This review focused on the clinical research about cracked tooth, which was providing thoughtway to diagnosis and therapy of cracked tooth. Related Articles | Metrics

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Research progress on manufacturing factors of the fracture about nickel-titanium CHEN Xiao-chun, CHEN Xin-mei Inter J Stomatol. 2009, 36 (3):  358-360.  DOI: 10.3969/j.issn.1673-5749.2009.03.033 Abstract ( 1502 )   HTML ( 5 )   PDF（pc） (109KB) ( 954 )   Save Although the nickel-titanium（Ni-Ti） alloy with super-elastic property is more and more used in endodontics, it has been reported that rotary Ni-Ti instruments are more prone to intracanal fracture compared with stainless steel instruments. These unexpected fractures occur without any visible changes to the instruments which produce a prominence problem creating a major obstacle to normally routine therapy. Many studies showed that the presence of defects on and in the Ni-Ti instruments before used restrict clinical application. In recent years, considerable attempt has been undertaken to improve these condition and produced more flexible and resistant Ni-Ti endodontic instruments, which may minimize the occurrence of fractures. This article reviewed the development of manufacturing methods of Ni-Ti endodontic instrument. Related Articles | Metrics

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The role of methyl mercaptan in the etiology of periodontitis MA Qin-rui, HE Yong-hong, WAN Hu-chun Inter J Stomatol. 2009, 36 (3):  361-363.  DOI: 10.3969/j.issn.1673-5749.2009.03.034 Abstract ( 1522 )   HTML ( 3 )   PDF（pc） (110KB) ( 805 )   Save Methyl mercaptan is the metabolite of putative periodontal pathogen catalyzed by L-methionine-γ-lyase（METase）. It plays an important role in cytoskeletal reorganization through increasing permeability of mucosa, cell migration through inhibiting synthesis and secretion of collagen and extracellular matrix, and in collagen degradation and alveolar bone resorption through immunological activities. Production of methyl mercaptan declines with inhibiting the enzyme activity. The objective of this article was to review the production of methyl mercaptan and the relationship of methyl mercaptan and periodontitis. Related Articles | Metrics

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Research progress of orthopedic treatment on facial bone with implant anchorage i CANG Song, BAI Yu-xing, WANG Bang-kang Inter J Stomatol. 2009, 36 (3):  364-366.  DOI: 10.3969/j.issn.1673-5749.2009.03.035 Abstract ( 1490 )   HTML ( 3 )   PDF（pc） (110KB) ( 822 )   Save Stable anchorage on orthopedic treatment is very important. Orthodontists routinely use teeth for the application of force to bone to effect skeletal change. Unfortunately, this indirect application of force limits the potential for orthopedic change and often causes undesirable tooth movement and root resorption. Hence, using of skeletal anchorage to apply force directly to bone would be more desirable. Recently, dental implants are used foranchorage on orthopedic treatment in orthodontics because of their good biocompatibility. Scholars do a lot of substructure and clinic research on orthopedic treatment in orthodontics. In the article, we reviewed orthopedic treatment on facial bone with implant anchorage in orthodontics. Related Articles | Metrics

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Research progress of root filling material removal by modern methods of root trea XIA Qian, GUO Bin Inter J Stomatol. 2009, 36 (3):  367-369，373.  DOI: 10.3969/j.issn.1673-5749.2009.03.036 Abstract ( 1413 )   HTML ( 7 )   PDF（pc） (135KB) ( 1129 )   Save The re-treatment of failed endodontic treatment includes complete removal of the root filling material, shaping root canals, disinfection with medicaments and ultimately filling. Removing as much filling material as possible is very essential for success. However, one of the greatest difficulties faced by re-treatment is achieving complete removal of filling materials. With the development of modern instruments and techniques, stainless steel hand files, engine-driven rotary files, solvents, heat-carrying and ultrasonic instruments are helpful devices aiming to remove completely the root filling material. This review was undertaken of the current literature on modern methods of filling material removal. Related Articles | Metrics

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Research advance of the jaw bone density KANG Ning, GONG Ping Inter J Stomatol. 2009, 36 (3):  370-373.  DOI: 10.3969/j.issn.1673-5749.2009.03.037 Abstract ( 1352 )   HTML ( 2 )   PDF（pc） (136KB) ( 837 )   Save The measurement of the jaw bone density is vital to the diagnosis and treatment of the periodontal disease and oral implant prosthesis, and it is one of the major topics in oral medicine for a long time. With the development of modern measurement instrument, widely used of non-invasive and high accuracy measurement technology of bone density, great progress has been made in the jaw bone density measurement recently. The ionizing radiation measurement is the most popular technology used in domestic and international characterized by low cost and good performance in measurement accuracy, while the non-ionizing radiation measurement is more safer and environment-protected by avoiding the dangers of radiation. In this paper, the progress of jaw bone density measurement was reviewed in both the ionizing radiation and non-ionizing radiation measurement fields. Related Articles | Metrics

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The clinical application of hard palatal mucoperiosteum flap YAN Guang-tang, LIANG Shang-zheng Inter J Stomatol. 2009, 36 (3):  374-376.  DOI: 10.3969/j.issn.1673-5749.2009.03.038 Abstract ( 1564 )   HTML ( 2 )   PDF（pc） (99KB) ( 1253 )   Save Hard palatal mucoperiosteum flap has merits of manufacturing easily and high survival rate. It can be manufactured pedicle flap with blood vessel, random flap, free flap to repair the defects of soft tissues of oral maxillofacial region, especially to the defects of smaller area on oral soft tissues. This article was an overview of clinical application of hard palatal mucoperiosteum flap, proposing to provide choices to clinical surgical works. Related Articles | Metrics