Int J Stomatol

Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (5): 597-602.doi: 10.7518/gjkq.2018.05.017

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Long non-coding RNA associated with p53 and the relationship with tumor

Tongtong Han,Qiaoer Chen(),Youming. Zhu   

  1. School of Stomatology, Anhui Medical University, Hefei 230032, China
  • Received:2017-10-22 Revised:2018-03-09 Online:2018-09-01 Published:2018-09-20
  • Contact: Qiaoer Chen E-mail:chqe0111@163.com

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Abstract:

p53 gene is a negative regulator of cell growth which can suppress the tumor through the regulation of cell proliferation and apoptosis under normal circumstances. The mutation of p53 often lead to the tumorigenesis. Recently, Long non-coding RNA (lncRNA) was identified as having a function role in the tumorigenesis and development of a variety of tumors. The review aimed to discuss the relationship of LncRNA which associated with p53 and oral cancer, and provide new strategies for patients with oral cancer.

Key words: p53, long non-coding RNA, tumors, oral cancer

CLC Number: 

  • R782

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