Int J Stomatol

Inter J Stomatol ›› 2015, Vol. 42 ›› Issue (1): 48-53.doi: 10.7518/gjkq.2015.01.014

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Function of microRNAs in oral lichen planus

Liu Jiajia, Wu Yuanqin, Zeng Xin, Zhou Yu.   

  1. State Key Laboratory of Oral Diseases, Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Online:2015-01-01 Published:2015-01-01

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Abstract:

MicroRNAs(miRNAs) have attracted increasing attention because of their important roles in regulating gene expression. Gene regulation by miRNAs is involved in various biological processes, such as cell proliferation, apoptosis and metabolism, growth, differentiation, vascularization, and immune response. The expression spectrum and changes of miRNAs are closely related to the occurrence and development of various diseases, such as tumor, inflammatory diseases, and autoimmune diseases. This article reviews the current research statuses of miRNAs in oral lichen planus.

Key words: microRNA, autoimmune diseases, oral lichen planus


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