Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (3): 332-335.doi: 10.3969/j.issn.1673-5749.2012.03.014

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Research progress on quorum sensing inhibitors in oral microbiol area

Wang Shuang1, Zhang Liping1, Xu Yi1,2.   

  1. 1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China; 2. Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2011-07-26 Revised:2012-01-18 Online:2012-05-01 Published:2012-05-01

Abstract:

Quorum sensing systems are bacterial cell -to-cell communication systems. Some natural substances and chemical compounds found recently interfere with quorum sensing systems. In this review we highlight inhibitors of acylhomoserine lactone and LuxS/AI-2 mediated quorum sensing in gram-negative bacteria and the corresponding research outcomes in the oral microbiol area.

Key words: quorum sensing, inhibitor, autoinducer


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