Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (4): 416-418.doi: 10.3969/j.issn.1673-5749.2011.04.013

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Research progress on gene involved in non-syndromic tooth agenesis

Ye Niansong, Wang Sheng, Lai Wenli.   

  1. Dept. of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2010-11-19 Revised:2011-01-24 Online:2011-07-20 Published:2011-07-20

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Abstract:

Tooth agenesis refers to tooth absence during tooth development, including hypodontia, oligodontia and anodontia. Tooth agenesis, which is grouped into syndromic and non-syndromic（isolated） types according to the existence of concomitant abnormalities, could be trigered by autosomal dorminant, autosomal recessive and X-linkage inheritence under either family or isolated backgroud. Progress involving paired box gene-9, muscle segment homeobox gene-1, axis inhibitor-2, ectodermal dysplasia in associate with non-syndromic tooth agenesis is reviewed here.

Key words: non-syndromic tooth agenesis, paired box gene, muscle segment homeobox gene, axis inhibitor, ectodermal dysplasia


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