Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (1): 110-112.doi: 10.3969/j.issn.1673-5749.2012.01.030

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Migration inhibitory factor and effect of its on periodontal diseases

Zhao Danfeng, Gong Qimei, Ling Junqi.   

  1. Dept. of Conservative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou 510055, China
  • Received:2010-08-28 Revised:2011-07-18 Online:2012-01-01 Published:2012-01-01

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Abstract:

Migration inhibitory factor（MIF） is described as a potent pro-inflammatory mediator that inhibited the migration of macrophages, which plays an important role in the regulation of physiological, pathological and immunologic response processes. Special emphasis is placed on the emerging concept that MIF has a central role as a regulator of inflammatory responses, and the implications it might have for the development of periodontal diseases.

Key words: migration inhibitory factor, periodontal diseases, cytokine


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