Inter J Stomatol ›› 2015, Vol. 42 ›› Issue (1): 59-62.doi: 10.7518/gjkq.2015.01.016

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Advances in the patterns and pathways of bone invasion by oral cancers

Li Chunjie1, Li Bo1, Li Longjiang1, Shi Zongdao2   

  1. 1. State Key Laboratory of Oral Diseases, Dept. of Head and Neck Tumor Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China; 2. State Key Laboratory of Oral Diseases, Dept. of Oral and Maxillofacial Surgery Clinic, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2014-02-08 Revised:2014-10-29 Online:2015-01-01 Published:2015-01-01

Abstract: Oral cancer grows invasively and is a common malignancy that invades bone tissues. Mandibular involvement is a key aspect in the treatment and prognosis of oral cancer. The preservation of the mandible, an important functional organ, has attracted increasing attention. However, the procedures for mandible preservation and mandibulectomy are inconsistent among oral and maxillofacial surgeons. The discrepancies are primarily caused by the uncertainty of the exact patterns of bone invasion by oral cancers. This article reviews the present materials to explore the mechanisms involved in mandibular preservation and mandibulectomy in oral cancer treatment.

Key words: oral cancer, cancer invasiveness, mandible

CLC Number: 

  • R 739.8

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