Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (6): 769-772.doi: 10.7518/gjkq.2013.06.019

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Research progress on periodontal ligament stem cell

Lu Shaowen, Shui Yanqing   

  1. Dept. of Conservative Dentistry and Endodontics, Periodontics and Mucosa, The Affiliated Hospital of Stomatology, Kunming Medical University, Kunming 650031, China
  • Received:2013-04-23 Revised:2013-07-23 Online:2013-11-01 Published:2013-11-01

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Abstract:

Periodontitis is a chronic inflammatory disease caused by dental plaque biofilm. It is a disease of the periodontium characterized by irreversible loss of connective tissue attachment and supporting alveolae, which may result in tooth loss. The aim of therapy is to regenerate the destroyed connective tissue attachment and supporting alveolae. Mesenchymal stem cells obtained from periodontal ligament are multipotent cells. These cells proliferate and differentiate into different types of tissues. Thus, mesenchymal stem cells are valuable for periodontal regeneration and periodontal tissue engineering. This review provides an overview of periodontal ligament stem cells and discusses recent studies and research prospects.

Key words: periodontal tissue engineering, periodontal ligament stem cell, challenge, pros, stem cell, periodontal tissue regeneration, periodontal ligament

CLC Number: 

  • Q 254

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