Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (4): 433-435.doi: 10.3969/j.issn.1673-5749.2011.04.018

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Research progress on T lymphocyte subsets of oral lichen planus

Liu Yajing, Wang Wenmei.   

  1. Dept. of Oral Medicine, The Affiliated Nanjing Stomatological Hospital of Medical College, Nanjing University, Nanjing 210008, China
  • Received:2010-12-18 Revised:2011-02-21 Online:2011-07-20 Published:2011-07-20

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Abstract:

Oral lichen planus（OLP） is a chronic autoimmune disease of oral mucosal accompanied with lesions of skin, gential tract, nails and hair. The histology of OLP is characterized by a dense subepithelial band-like infiltrate of T lymphocytes, disruption of the epithelial basement membrane and degeneration of basal keratinocytes. This paper reviewed the research progresses of CD4+/CD8+ T cells and OLP, memory/naive T cells and OLP, Th1, Th2, Th9, Th17 cells and OLP, regulatory T cells and OLP, etc.

Key words: oral lichen planus, T lymphocyte subsets, cell-mediated immunity


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