Int J Stomatol

Inter J Stomatol ›› 2010, Vol. 37 ›› Issue (5): 555-558.doi: 10.3969/j.issn.1673-5749.2010.05.017

Previous Articles     Next Articles

Research advances of immunomodulatory treatment applied in periodontitis

GUO Ye, ZHAO Lei, WU Yafei.   

  1. Dept. of Periodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China
  • Online:2010-09-20 Published:2010-09-20

RichHTML

7

PDF (PC)

1350

Abstract:

Periodontitis is a chronic infection caused by bacteria in dental plaque which is characterized by destruction of periodontal tissues caused by direct aggression of bacteria and host response. When periodontal tissues were stimulated by bacteria, a series of inflammatory signal pathways were activated and the expression of inflammatory mediators increased. Therefore, development of periodontitis may be regulated via the mediation of signaling pathways and inflammatory mediators. There were substantial researches concerning immunomodulatory treatment, and this article aimed to review new progress of immunomodulatory treatment applied in periodontitis.

Key words: host immune response, inflammatory response, immunomodulatory treatment, signal pathway, inflammatory mediator


TrendMD: 
[1] Liu Siyu,Li Xin,Xu Xiaoyu,Sun Yinyin,Pan Yingxiao,Wang Sainan,Lu Shulai. Research advances in the relationship between oral lichen planus and cardiovascular diseases [J]. Int J Stomatol, 2021, 48(2): 141-146.
[2] Zhu Bowen,Chen Limei,Guo Zhuling. Review of NLRP3 inflammasomes in periodontal diseases [J]. Int J Stomatol, 2019, 46(4): 450-455.
[3] Xue Lingfa, Zhang Daizun, Xiao Wenlin, Yu Baojun. Mechanical strain induces mouse bone mesenchymal stem cells osteogenic differentiation [J]. Inter J Stomatol, 2017, 44(6): 679-685.
[4] Ding Ye, Ren Jingyi, Yu Hongqiang, Zhou Yanmin, Yu Weixian. Roles of pathogen-associated and damage-associated molecular patterns in immune inflammatory response [J]. Inter J Stomatol, 2016, 43(2): 172-176.
[5] Wu Leng, Wang Jun, Zhao Lei, Wu Yafei.. Nucleotide-binding oligomerization domain-like-receptor family pyrin domain-containing 3 inflammasomes and the relationship between it and periodontal diseases [J]. Int J Stomatol, 2015, 42(6): 710-714.
[6] Zhan Xueling, Gao Jie, Wu Buling. Role and significance of Toll-like receptors 2 and 4 signaling pathway in inflammatory treatment [J]. Inter J Stomatol, 2014, 41(3): 304-308.
[7] RONG Qiong1, HU Yan2.. Effects of desmosome and signal pathways in the pathogenesis of pemphigus [J]. Inter J Stomatol, 2011, 38(2): 192-196.
[8] GUO Ping1, LIN Xin-ping2.. Effect and regulatory mechanisms of mechanical strain on the expression of core binding factor-α1 [J]. Inter J Stomatol, 2011, 38(2): 218-220.
[9] TU Yan, CHEN Hui. Mechanism of cardiovascular disease caused by oral infection [J]. Inter J Stomatol, 2010, 37(02): 182-182～185.
[10] CHEN Yi -yang, HUANG Hong-zhang. Transforming growth factor -beta -Smad signal pathway in the development of palat [J]. Inter J Stomatol, 2008, 35(6): 650-650～653.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[9] . [J]. Foreign Med Sci: Stomatol, 2004, 31(02): 126 -128 .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .