国际口腔医学杂志 ›› 2024, Vol. 51 ›› Issue (2): 193-200.doi: 10.7518/gjkq.2024005
张宇1(),贾志宇2,唐慧芳1,张志勇1,李文静1,田松波1(
)
Yu Zhang1(),Zhiyu Jia2,Huifang Tang1,Zhiyong Zhang1,Wenjing Li1,Songbo Tian1(
)
摘要:
免疫球蛋白G4相关性唾液腺炎(IgG4-RS)是一种与IgG4密切相关的慢性自身免疫性疾病,其发病率低,病因和发病机制尚不明确,以唾液腺尤其是颌下腺无痛性持续性肿大为主要临床表现,多数患者血清IgG4升高,淋巴浆细胞浸润,后期全身多器官可继发病变,组织病理学是该病最可靠的诊断方法。临床上倾向于传统糖皮质激素作为首选用药,现阶段可尝试应用生物制剂进行靶向治疗。本文根据国内外文献,对IgG4-RS的病因、临床表现、诊断与鉴别诊断、治疗和预后的研究进展作一综述,以期为该病的临床诊疗和研究提供帮助。
中图分类号:
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