国际口腔医学杂志

国际口腔医学杂志 ›› 2023, Vol. 50 ›› Issue (4): 388-394.doi: 10.7518/gjkq.2023053

• 牙体牙髓病学专栏 • 上一篇    下一篇

根管内感染控制对年轻恒牙牙髓再生治疗的影响及研究进展

吴思佳(),舒畅,王洋,王媛,邓淑丽,王慧明()   

  1. 浙江大学医学院附属口腔医院 浙江大学口腔医学院 浙江省口腔疾病临床医学研究中心浙江省口腔生物医学研究重点实验室 浙江大学癌症研究院 杭州 310006
  • 收稿日期:2022-09-02 修回日期:2023-03-02 出版日期:2023-07-01 发布日期:2023-06-21
  • 通讯作者: 王慧明
  • 作者简介:吴思佳，住院医师，硕士，Email：22018586@zju.edu.cn
  • 基金资助:
    浙江省“尖兵”“领雁”研发攻关计划(2022C03060)

Effect and research progress on root canal infection management of regenerative endodontic procedure in immature permanent teeth

Wu Sijia(),Shu Chang,Wang Yang,Wang Yuan,Deng Shuli,Wang Huiming.()   

  1. Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China
  • Received:2022-09-02 Revised:2023-03-02 Online:2023-07-01 Published:2023-06-21
  • Contact: Huiming. Wang
  • Supported by:
    “Pioneer” and “Leading Goose” Research and Development Program in Zhe-jiang Province(2022C03060)

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摘要：

牙髓再生治疗（REP）中根管内感染控制至关重要，包括根管冲洗和根管内封药2个过程。根管内残留细菌、根管冲洗剂和药物的细胞毒性等与根管内感染控制相关的因素会影响REP的预后，因此需要寻求最佳的根管内感染控制方案，以满足抗菌功效和利于组织再生的要求。新型根管冲洗剂、冲洗技术以及新型抗菌支架的研发和应用，能够减小其对REP的不利影响，具有良好的应用前景。本文拟讨论根管内感染控制对REP的影响，并对其前沿进展进行综述。

关键词: 牙髓再生治疗, 感染控制, 残留细菌, 细胞毒性, 抗菌效果

Abstract:

Root canal infection management is a crucial step in regenerative endodontic procedure (REP), which include root canal irrigation and intracanal medicaments. Various factors, such as residual microorganisms or the cytotoxicity of root canal irrigants and drugs, affect the outcomes of REP. Scholars should search for an optimum infection management remedy to acquire sufficient antimicrobial efficacy and proper environment for tissue regeneration. The development of novel canal irrigants and irrigation techniques and the exploration of novel antibacterial scaffold can alleviate the adverse effects of REP. This article intends to discuss the influences of infection management on REP and elucidate its promising advances.

Key words: regenerative endodontic procedure, infection management, residual microorganism, cytotoxicity, antibacterial efficacy

中图分类号: 

  • R 781.33
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