国际口腔医学杂志

国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (6): 666-672.doi: 10.7518/gjkq.2018.06.008

• 材料学专栏 • 上一篇    下一篇

天然支架材料在牙髓组织工程再生中的研究进展

李龙飚,汪成林,叶玲()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院牙体牙髓病科 成都 610041
  • 收稿日期:2017-12-11 修回日期:2018-05-23 出版日期:2018-11-01 发布日期:2018-11-15
  • 通讯作者: 叶玲
  • 作者简介:李龙飚,学士,Email： 1094162752@qq.com
  • 基金资助:
    科学技术部国际合作专项基金(2014DFA31990)

Research progress on natural scaffold in the regeneration of dental pulp tissue engineering

Longbiao Li,Chenglin Wang,Ling Ye()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2017-12-11 Revised:2018-05-23 Online:2018-11-01 Published:2018-11-15
  • Contact: Ling Ye
  • Supported by:
    This study was supported by Special Fund for International Cooperation of the Ministry of Science and Technology(2014DFA31990)

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摘要：

组织工程为牙髓再生带来了新的可能性,支架材料在其中扮演着重要作用,受到了越来越多的关注。天然支架材料是指从动植物组织中提取的可降解材料,其特点是与细胞外基质相似度高,或本身就是细胞外基质的组成部分,通常具有良好的生物活性、亲水性、材料与细胞界面相容性。目前,进入牙髓组织工程动物实验或临床应用研究的支架材料皆为天然支架材料,本文就牙髓组织工程再生中各种天然支架材料的分类、优缺点及应用等研究进展作一综述。

关键词: 牙髓组织工程, 牙髓再生, 支架材料

Abstract:

Tissue engineering has brought new possibilities for dental pulp regeneration. Scaffold materials play an important role in it, and have attracted more and more attention. Natural scaffold material is a biodegradable material extracted from animal or plant tissue, which is characterized by high similarity with extracellular matrix, or itself as part of extracellular matrix, usually with good bioactivity, hydrophilicity, and compatibility of material and cell interface. At present, the scaffolds for the research of dental pulp tissue engineering animal experiment or clinical application are all natural scaffold materials. This article reviews the research progress on the classification, advantages and disadvantages and application of various natural scaffold materials in the regeneration of dental pulp tissue engineering.

Key words: dental pulp tissue engineering, pulp regeneration, scaffold

中图分类号: 

  • R318.08
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