Int J Stomatol ›› 2022, Vol. 49 ›› Issue (5): 506-510.doi: 10.7518/gjkq.2022083

• Oral Microbiology • Previous Articles     Next Articles

Research progress on sugar transporter and regulatory mechanisms in Streptococcus mutans

Gong Tao(),Li Yuqing,Zhou Xuedong.()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China School of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2022-01-06 Revised:2022-05-08 Online:2022-09-01 Published:2022-09-16
  • Contact: Xuedong. Zhou;
  • Supported by:
    National Natural Science Foundation of China(81670978)


Dental caries is one of the most prevalent infectious diseases. Streptococcus mutans (S. mutans) is regarded as the major etiological pathogen. Sugars are the major carbohydrate sources used by bacteria and act as important substance basis for energy metabolism, material metabolism and physiological functions. Sugar transporter is the first process of sugar metabolism and is closely related to the formation of cariogenic virulence factors of S. mutans. This article reviewed the research progress on the ways of sugar transporter and its regulatory mechanisms of S. mutans to provide a reference for the research of sugar transport-related mechanisms in other oral bacterial.

Key words: dental caries, Streptococcus mutans, sugar transporter, regulatory mechanisms

CLC Number: 

  • R 788


Fig 1

PTS and ABC transporter"

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