国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (1): 32-35.doi: 10.7518/gjkq.2018.01.006

• 综述 • 上一篇    下一篇

改良介孔生物活性玻璃在颌面部骨缺损修复中的研究进展

汪洋1, 申玉芹2, 于文雯1, 孙新华1   

  1. 1.吉林大学口腔医院正畸科 长春 130021
    2.吉林大学口腔医院牙周科 长春 130021
  • 收稿日期:2017-05-28 修回日期:2017-10-24 出版日期:2018-01-01 发布日期:2018-01-01
  • 通讯作者: 孙新华,教授,学士,Email:xinhuasun8@163.com
  • 作者简介:汪洋,硕士,Email:1138431264@qq.com
  • 基金资助:
    国家自然科学基金(81371153); 吉林省科学技术厅自然科学基金项目(20150101173JC); 白求恩前沿交叉学科创新项目(20131080031)

Reasearch progress on modified mesoporous bioactive glasses for repairing maxillofacial bone defects

Wang Yang1, Shen Yuqin2, Yu Wenwen1, Sun Xinhua1   

  1. 1. Dept. of Orthodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China
    2. Dept. of Periodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2017-05-28 Revised:2017-10-24 Online:2018-01-01 Published:2018-01-01
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81371153), Jilin Provincial Science and Technology Department Natural Science Fund (20150101173JC) and Interdisciplinary Innovation Project of Bethune (20131080031).

摘要: 介孔生物活性玻璃是一类能够与骨组织形成键合作用的多孔径生物活性材料,具有良好的生物相容性、生物降解性、骨生成和骨传导性能,在骨组织工程领域具有极大的潜力。近年来,研究者致力于改变介孔生物活性玻璃结构的研究,以提高其生物学性能,从而提升其潜在的临床应用价值。本文就改良介孔生物活性玻璃在颌面部骨缺损修复领域的研究进展进行综述。

关键词: 改良介孔生物活性玻璃, 颌面部骨缺损, 修复

Abstract: Mesoporous bioactive glasses is a kind of bioactive material that exhibits a bonding effect with bone tissues. They possess high biocompatibility, biodegradability and good bone formation and conduction properties, which are essential for bone tissue engineering applications. With the aim of increasing their clinical value, researchers in recent years have improved the performance of mesoporous bioactive glasses by reforming their structures. This article provides a brief review on the research progress of modified mesoporous bioactive glasses for maxillofacial bone defect repair.

Key words: modified mesoporous bioactive glasses, maxillofacial bone defects, repairment

中图分类号: 

  • R782.2+3
[1]Hench LL, Jones JR. Bioactive glasses: frontiers and challenges[J]. Front Bioeng Biotechnol, 2015, 3:194.
[2]Kaur G, Pickrell G, Kimsawatde G et al. Synthesis, cytotoxicity, and hydroxyapatite formation in 27- Tris-SBF for sol-gel based CaO-P 2 O 5 -SiO 2 -B 2 O 3 -ZnO bioactive glasses[J]. Sci Rep, 2014, 4:4292.
[3]张爱娟, 高增丽. 硼对模拟体液中生物活性玻璃矿化速度的影响[J]. 硅酸盐通报, 2015, 34(12):3721- 3725 Zhang AJ, Gao ZL. The effect of boron on bioactive glass mineralization rate in simulated humors[J]. Bull Chin Ceramic Soc, 2015, 34(12):3721-3725.
[4]Azevedo MM, Tsigkou O, Nair R, et al. Hypoxia inducible factor-stabilizing bioactive glasses for di-recting mesenchymal stem cell behavior[J]. Tissue Eng Part A, 2015, 21(1/2):382-389.
[5]Coraça-Huber DC, Fille M, Hausdorfer J, et al. Efficacy of antibacterial bioactive glass S53P4 against S. aureus biofilms grown on titanium discs in vitro [J]. J Orthop Res, 2014, 32(1):175-177.
[6]贺金晶. 含铜介孔生物活性玻璃/多孔羟基磷灰石复合支架的制备及其义眼座应用的基础研究[D]. 杭州: 浙江大学, 2014. He JJ. Preparation of bioactive glass/porous hydro-xyapatite composite scaffolds and basic research on the application of the prosthetic eyes[D]. Hangzhou:Zhejiang University, 2014.
[7]Zhao L, Yan X, Zhou X, et al. Mesoporous bioactive glasses for controlled drug release[J]. Microporo Mesoporo Mater, 2008, 109(1/2/3):210-215.
[8]Hong Y, Chen X, Jing X, et al. Preparation, bioac-tivity, and drug release of hierarchical nanoporous bioactive glass ultrathin fibers[J]. Adv Mater, 2010, 22(6):754-758.
[9]刘涛. 丝素蛋白、介孔生物玻璃陶瓷骨修复复合材料的制备与性能研究[D]. 杭州: 浙江大学, 2014. Liu T. Preparation and properties of fibroin and mesoporous ceramic bone repair composite materials [D]. Hangzhou: Zhejiang University, 2014.
[10]车晨, 耿亚亚, 郝葆青. 生物活性玻璃分子生物学特性的研究进展[J]. 内蒙古农业大学学报(自然科学版), 2015, 36(1):179-183. Che C, Geng YY, Hao BQ. Advances in molecular biological characteristics of bioactive glass[J]. J Inner Mongolia Argicul Univer (Nat Sci Ed), 2015, 36(1):179-183.
[11]Wu C, Zhou Y, Xu M, et al. Copper-containing mesoporous bioactive glass scaffolds with multifunc-tional properties of angiogenesis capacity, osteos-timulation and antibacterial activity[J]. Biomaterials, 2013, 34(2):422-433.
[12]张学广. 胶原膜及生物活性玻璃用于颌骨囊肿骨缺损修复[J]. 现代口腔医学杂志, 2002, 16(5):429- 430. Zhang XG. Collagen membrane and bioactive glass used in the repair of bone defect of maxilla cyst[J]. J Moden Stomatol, 2002, 16(5):429-430.
[13]Stoor P, Mesimäki K, Lindqvist C, et al. The use of anatomically drop-shaped bio-active glass S53P4 implants in the reconstruction of orbital floor frac-tures—a prospective long-term follow-up study[J]. J Cranio-maxillo-fac Surg, 2015, 43(6):969-975.
[14]van Gestel NAP, Geurts J, Hulsen DJW, et al. Clin-ical applications of S53P4 bioactive glass in bone healing and osteomyelitic treatment: a literature review[J]. 2015, 2015:684826.
[15]McAndrew J, Efrimescu C, Sheehan E, et al. Through the looking glass: bioactive glass S53P4 (Bone Alive ® ) in the treatment of chronic osteomyelitis[J]. Ir J Med Sci, 2013, 182(3):509-511.
[16]Drago L, Romanò D, De Vecchi E, et al. Bioactive glass BAG-S53P4 for the adjunctive treatment of chronic osteomyelitis of the long bones: an in vitro and prospective clinical study[J]. BMC Infect Dis, 2013, 13:584.
[17]Detsch R, Stoor P, Grünewald A, et al. Increase in VEGF secretion from human fibroblast cells by bioactive glass S53P4 to stimulate angiogenesis in bone[J]. J Biomed Mater Res A, 2014, 102(11):4055- 4061.
[18]Lindfors NC, Koski I, Heikkilä JT, et al. A prospec-tive randomized 14-year follow-up study of bioactive glass and autogenous bone as bone graft substitutes in benign bone tumors[J]. J Biomed Mater Res B Appl Biomater, 2010, 94(1):157-164.
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