Int J Stomatol

Int J Stomatol ›› 2025, Vol. 52 ›› Issue (1): 25-33.doi: 10.7518/gjkq.2025018

• Oral Oncology • Previous Articles     Next Articles

Application of carbon dots to the diagnosis and treatment of oral and maxillofacial malignant tumors

Tianyu Fu1(),Xue Zhang2,Siqi Wang1,Chengyi Guo1,Xiaoyu Dong1,Yapeng Cheng1,Rui Li3()   

  1. 1.School of Stomatology, Zhengzhou University, Zhengzhou 450052, China
    2.Dept. of Oral Medicine, the First Affilia-ted Hospital of Zhengzhou University, Zhengzhou 450052, China
    3.Dept. of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  • Received:2024-06-15 Revised:2024-09-02 Online:2025-01-01 Published:2025-01-11
  • Contact: Rui Li E-mail:3129531805@qq.com;liruisichuan@163.com

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Abstract:

Owing to advancements in nanomaterials and diagnostic and therapeutic modalities, nanomedicine has attracted considerable interest. Carbon dots are zero-dimensional nanomaterials with fluorescent properties and applicable to the diagnosis and treatment of oral cancer. They potentially enhance detection sensitivity, reduce adverse drug reactions, and improve therapeutic efficacy, thereby providing a new avenue for the management of oral cancer. This paper reviews progress in research on carbon-dot-based strategies for oral cancer diagnosis and treatment and their applications in chemotherapy, photodynamic therapy, photothermal therapy, and immunotherapy. It also explores the feasibility of using carbon dots in oral cancer management and potential development in the biomedical field.

Key words: carbon dots, oral cancer, diagnosis, chemotherapy, photodynamic therapy, photothermal therapy, immunotherapy

CLC Number: 

  • R739.8

TrendMD: 

Fig 1

The schematic diagram of the principle of PDT"

Fig 2

The schematic diagram of the principle of PTT"

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