Int J Stomatol

Int J Stomatol ›› 2025, Vol. 52 ›› Issue (3): 405-410.doi: 10.7518/gjkq.2025027

• Reviews • Previous Articles    

Progress of research on the application of indocyanine green fluorescence imaging technology in the surgical treatment of oral squamous cell carcinoma

Maikeliya Aikepaer1(),Maimaitituxun Tuerdi1,2()   

  1. 1.Dept. of Oral and Maxillofacial Trauma and Orthognathic Surgery, First Affiliated Hospital (Stomatological Hospital) of Xinjiang Medical University, Urumqi 830054, China
    2.Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi 830054, China
  • Received:2024-04-20 Revised:2024-10-16 Online:2025-05-01 Published:2025-04-30
  • Contact: Maimaitituxun Tuerdi E-mail:943126491@qq.com;maimaitituxun@aliyun.com;maimai-tituxun@aliyun.com
  • Supported by:
    National Natural Science Foundation of China(82360198)

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Abstract:

The surgical resection of oral squamous cell carcinoma (OSCC) mostly relies on the experience of clinicians, such as visual examination, palpation, and preoperative imaging examination. Real-time and objective intraoperative evaluation methods are also lacking. Indocyanine green (ICG) is a safe and pollution-free organic fluorescent dye that accumulates and develops at a lesion under near-infrared (NIR) fluorescence. This technique can be applied in the visua-lization of primary tumors and surrounding blood vessels and nerves, sentinel lymph-node biopsy, cervical lymph-node dissection, and the evaluation of free-flap blood supply for the repair and reconstruction of OSCC. NIR imaging technology may become a key link in the early diagnosis and precise treatment of OSCC in the future. This article reviews the application of ICG-NIR in OSCC.

Key words: indocyanine green, near infrared fluorescence imaging, oral squamous cell carcinoma

CLC Number: 

  • R739.8

TrendMD: 
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