Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (2): 145-149.doi: 10.7518/gjkq.2018.02.005

• Oral Medicine • Previous Articles     Next Articles

Research progress on the etiology of recurrent aphthous ulcer in children

Cai Donglin1, Lu Rui1,2   

  1. 1.The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) &Key Laboratory of Oral Biomedicine Ministry of Education, School of Stomatology, Wuhan University, Wuhan 430079, China;
    2.Dept. of Oral Medicine, Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2017-09-21 Revised:2017-11-02 Online:2018-03-01 Published:2018-03-01
  • Supported by:
    This study was supported by the Cultivation Project of Wuhan Young and Middle-aged Backbone Talent in Medicine (the fifth batch of 2017).

Abstract: Recurrent aphthous ulcer (RAU) is the most common ulcerative disease of the oral mucosa. Although RAU appears in all ages, the onset of RAU peaks during childhood. Childhood RAU, as a special patient group, displays distinct etiology. The etiology of childhood RAU includes genetic, local trauma, psychologic, nutritional factors, microbial infection, and abnormal immunologic response. Moreover, some cases of childhood RAU are associated with several systemic diseases. This article presents the current progress on the etiology of RAU in children.

Key words: recurrent aphthous ulcer, children, etiology

CLC Number: 

  • R781.5

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