Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (6): 790-794.doi: 10.7518/gjkq.2013.06.024

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Commonly used surgical methods and progress in clinical treatment of Crouzon syndrome

Liu Lan, Zhang Kailiang, Yang Lan   

  1. Dept. of Oral and Maxillofacial Surgery, The Second Hospital of Lanzhou Uuniversity, Lanzhou 730030, China
  • Received:2013-03-28 Revised:2013-07-19 Online:2013-11-01 Published:2013-11-01

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Abstract:

Crouzon syndrome is an autosomal dominant hereditary disease caused by craniosynostosis that is characterized by hypsicephaly and facial abnormalities such as surface central sag and exophthalmos. Treatment mainly includes surgery, physical therapy, and gene therapy. In particular, surgery is the primary treatment modality and it can be used for a variety of complications. Currently, surgical treatment is merely a remedy for Crouzon syndrome. Future clinical research will determine whether Crouzon syndrome can be diagnosed during embryonic development through gene technology, as well as preventing and blocking the occurrence of Crouzon syndrome through medical treatment. This paper reviews the progress on the surgical timing and treatment methods for Crouzon syndrome.

Key words: Crouzon syndrome, surgical method, gene therapy, advances

CLC Number: 

  • R 782.05

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