Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (1): 48-51.doi: 10.3969/j.issn.1673-5749.2012.01.013

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Biological therapy for dentin-pulp complex regeneration and repair

Luo Chuanxia1,2, Lin Zhengmei1.   

  1. 1. Dept. of Conservative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat- Sen University, Guangzhou 510055, China; 2. Dept. of Stomatology, Guangzhou Panyu Central Hospital, Guangzhou 511400, China
  • Received:2010-12-26 Revised:2011-11-04 Online:2012-01-01 Published:2012-01-01

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Abstract:

Safe and effective approaches for dentin-pulp complex regeneration and repair are the focus of scientist’s research around the conservative dentistry. Whereas, all current therapies have limitations. Gene therapy and stem cell-based therapy which are brand-new biological therapies build more favorable situation for tissue regeneration and repair comparing with traditional treatment. This review will summarize current knowledge of gene-and stem cell-based therapies for dentin-pulp complex regeneration and repair.

Key words: dental pulp exposure, repair, gene therapy, stem cell-based therapy


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