Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (6): 742-745.doi: 10.3969/j.issn.1673-5749.2012.06.012

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Biological effects of lipoteichoic acid from Streptococcus mutans

Zhang Ya, Yu Danni.   

  1. Dept. of Stomatology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China
  • Received:2012-02-03 Revised:2012-08-13 Online:2012-11-01 Published:2012-11-01

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Abstract:

Lipoteichoic acid, the virulence factor of Streptococcus mutans（S.mutans）, plays an important role in dental caries caused by S.mutans and induces dental pulp immune response during the advances in dental caries. Research progress reviewed in this paper is the biological effects of lipoteichoic acid from S.mutans, including structure and functions, periodontal disease progress, complement activation, production of cytokine, and apotosis of pulp cells.

Key words: Streptococcus mutans, lipoteichoic acid, biological effects


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