国际口腔医学杂志 ›› 2026, Vol. 53 ›› Issue (5): 719-727.doi: 10.7518/gjkq.2026020
• 综述 • 上一篇
摘要:
美学区种植体周围龈乳头的恢复是口腔种植修复中实现美学与功能协调的关键环节,其高度退缩会直接影响种植体的功能和美学效果。种植体周围龈乳头的解剖结构特殊,重建效果和重建后长期稳定性一直是困扰临床医生的难题。本文从龈乳头的解剖基础、影响因素及重建策略三大方面进行分析,总结认为影响美学区种植体周围龈乳头高度的关键因素包括解剖因素、手术因素、修复设计因素及患者个体因素,当前的重建策略主要包括传统外科增量技术与新型生物技术,为美学区种植治疗中龈乳头的保存及重建提供参考。
中图分类号:
| [1] | Tavelli L, Barootchi S, Avila-Ortiz G, et al. Peri-implant soft tissue phenotype modification and its impact on peri-implant health: a systematic review and network meta-analysis[J]. J Periodontol, 2021, 92(1): 21-44. |
| [2] |
Mahasneh SA, Goodwin M, Pretty I, et al. The use of radiographs to assess the impact of the distance between the contact area and the crest of the bone to predict the presence or absence of interdental papilla: an in vivo study[J]. Br Dent J, 2023. doi: 10. 1038/s41415-023-6184-z .
doi: 10. 1038/s41415-023-6184-z |
| [3] | Godani A, Iyer J, Nadgere J, et al. Impact of immediate interim restoration on peri-implant tissues around immediately placed single dental implants in the esthetic region: a systematic review and meta-analysis[J]. J Prosthet Dent, 2025, 134(4): 1075-1088. |
| [4] | Berlucchi I, Francetti L, Del Fabbro M, et al. The influence of anatomical features on the outcome of gingival recessions treated with coronally advanced flap and enamel matrix derivative: a 1-year prospective study[J]. J Periodontol, 2005, 76(6): 899-907. |
| [5] | Noverraz S, Noverraz Y, Xi T, et al. Influence of surgically assisted rapid maxillary expansion on the interdental papilla height of maxillary central incisors[J]. J Orofac Orthop, 2021, 82(6): 372-381. |
| [6] | Xiao YZ, Lin ZQ, Wang PS, et al. Relationship of gingival phenotypes and faciolingual thickness, papilla height, and gingival angle in a Chinese population[J]. Int J Periodontics Restorative Dent, 2021, 41(1): 127-134. |
| [7] | Yang G, Cao J, Hu WJ, et al. Measurements of the gingival papillae architecture using cone-beam computed tomography in young Chinese adults[J]. Peer-J, 2020, 8: e10006. |
| [8] | Albrektsson T, Johansson C. Osteoinduction, osteoconduction and osseointegration[J]. Eur Spine J, 2001, 10(): S96-S101. |
| [9] | Yuan X, Pei XB, Chen JL, et al. Comparative analyses of the soft tissue interfaces around teeth and implants: insights from a pre-clinical implant model[J]. J Clin Periodontol, 2021, 48(5): 745-753. |
| [10] | Abrahamsson I, Berglundh T, Wennström J, et al. The peri-implant hard and soft tissues at different implant systems. A comparative study in the dog[J]. Clin Oral Implants Res, 1996, 7(3): 212-219. |
| [11] | Chanthasan S, Mattheos N, Pisarnturakit PP, et al. Influence of interproximal peri-implant tissue and prosthesis contours on food impaction, tissue health and patients’ quality of life[J]. Clin Oral Implants Res, 2022, 33(7): 768-781. |
| [12] | Berglundh T, Armitage G, Araujo MG, et al. Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 World Workshop on the classification of periodontal and peri-implant disea-ses and conditions[J]. J Clin Periodontol, 2018, 45(): S286-S291. |
| [13] | Choquet V, Hermans M, Adriaenssens P, et al. Clinical and radiographic evaluation of the papilla level adjacent to single-tooth dental implants. A retrospective study in the maxillary anterior region[J]. J Pe-riodontol, 2001, 72(10): 1364-1371. |
| [14] | Salama H, Salama MA, Garber D, et al. The interproximal height of bone: a guidepost to predictable aesthetic strategies and soft tissue contours in ante-rior tooth replacement[J]. Pract Periodontics Aesthet Dent, 1998, 10(9): 1131-1141, 1142. |
| [15] | Jung RE, Heitz-Mayfield L, Schwarz F, et al. Evidence-based knowledge on the aesthetics and maintenance of peri-implant soft tissues: osteology foundation consensus report part 3-aesthetics of peri-implant soft tissues[J]. Clin Oral Implants Res, 2018, 29(): 14-17. |
| [16] | Papapanou PN, Sanz M, Buduneli N, et al. Perio-dontitis: consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Pe-riodontal and Peri-Implant Diseases and Conditions[J]. J Periodontol, 2018, 89(): S173-S182. |
| [17] | Fischer KR, Büchel J, Testori T, et al. Gingival phenotype assessment methods and classifications revi-sited: a preclinical study[J]. Clin Oral Investig, 2021, 25(9): 5513-5518. |
| [18] | Di Gianfilippo R, Valente NA, Toti P, et al. Influen-ce of implant mucosal thickness on early bone loss: a systematic review with meta-analysis[J]. J Perio-dontal Implant Sci, 2020, 50(4): 209-225. |
| [19] | Jung RE, Becker K, Bienz SP, et al. Effect of peri-implant mucosal thickness on esthetic outcomes and the efficacy of soft tissue augmentation procedures: consensus report of group 2 of the SEPA/DGI/OF workshop[J]. Clin Oral Implants Res, 2022, 33(): 100-108. |
| [20] | Souza AB, Tormena M, Matarazzo F, et al. The influence of peri-implant keratinized mucosa on brushing discomfort and peri-implant tissue health[J]. Clin Oral Implants Res, 2016, 27(6): 650-655. |
| [21] | Chen ST, Buser D, Sculean A, et al. Complications and treatment errors in implant positioning in the aesthetic zone: diagnosis and possible solutions[J]. Periodontol 2000, 2023, 92(1): 220-234. |
| [22] | Monje A, Roccuzzo A, Buser D, et al. Influence of buccal bone wall thickness on the peri-implant hard and soft tissue dimensional changes: a systematic review[J]. Clin Oral Implants Res, 2023, 34(3): 157-176. |
| [23] | Chen ST, Darby IB, Reynolds EC. A prospective cli-nical study of non-submerged immediate implants: clinical outcomes and esthetic results[J]. Clin Oral Implants Res, 2007, 18(5): 552-562. |
| [24] | Chandran KRS, Goyal M, Mittal N, et al. Accuracy of freehand versus guided immediate implant placement: a randomized controlled trial[J]. J Dent, 2023, 136: 104620. |
| [25] | 任帅吉, 杜静冰. 美学区单颗牙缺失即刻种植与拔牙位点保存后延期种植的临床效果分析[J]. 中国口腔种植学杂志, 2024, 29(6): 561-567. |
| Ren SJ, Du JB. Comparison of clinical outcomes between immediate implantation and delayed implantation following alveolar ridge preservation for single-tooth loss in the aesthetic zone[J]. Chin J Oral Implantol, 2024, 29(6): 561-567. | |
| [26] | Raj A, Pradhan S, Shetty P, et al. Comparison of crestal bone loss and papilla fill after conventional and immediate implant placement: a 12 month clinical and radiographic prospective study[J]. F1000-Res, 2023, 12: 821. |
| [27] | Atieh MA, Shah M, Abdulkareem M, et al. The socket shield technique for immediate implant placement: a systematic review and meta-analysis[J]. J Esthet Restor Dent, 2021, 33(8): 1186-1200. |
| [28] | MacLean S, Hermans M, Villata L, et al. A retrospective multicenter case series evaluating a novel 3.0-mm expanding tapered body implant for the rehabilitation of missing incisors[J]. Quintessence Int, 2016, 47(4): 297-306. |
| [29] | Frizzera F, Calazans NNN, Pascoal CH, et al. Flapless guided implant surgeries compared with conventional surgeries performed by nonexperienced individuals: randomized and controlled split-mouth clinical trial[J]. Int J Oral Maxillofac Implants, 2021, 36(4): 755-761. |
| [30] | Froum SJ, Wang WC, Hafez T, et al. Incision design and soft tissue management to maintain or establish an interproximal papilla around integrated implants: a case series[J]. Int J Periodontics Restorative Dent, 2018, 38(1): 61-69. |
| [31] | Luo W, Wang XY, Chen YQ, et al. Radiographic evaluation of a cross-shaped incision technique for thick-gingiva and thin-gingiva patients treated with implant-supported fixed prosthesis[J]. BMC Oral Health, 2021, 21(1): 655. |
| [32] | Lee EK, Herr Y, Kwon YH, et al. I-shaped incisions for papilla reconstruction in second stage implant surgery[J]. J Periodontal Implant Sci, 2010, 40(3): 139-143. |
| [33] | Parihar AS, Manas A, Gopinath PV, et al. A compa-rative study of mid-crestal incision and diode laser shaped incision to assess papilla level in second stage dental implant surgery[J]. J Pharm Bioallied Sci, 2022, 14(): S236-S238. |
| [34] | Saleh MHA, Urban IA, Alrmali A, et al. Papilla reconstruction using a vertical interproximal tunnel approach[J]. Int J Oral Implantol, 2023, 16(1): 55-64. |
| [35] | Kamakshi LNVA, Uppoor AS, Nayak DG, et al. Evaluation of papilla levels following three diffe-rent techniques for the second stage of implants-a clinical and radiographic study[J]. J Indian Soc Pe-riodontol, 2021, 25(2): 120-127. |
| [36] | Kois JC. Predictable single-tooth peri-implant esthetics: five diagnostic keys[J]. Compend Contin Educ Dent, 2004, 25(11): 895-896, 898, 900, 906-907. |
| [37] | Siegenthaler M, Strauss FJ, Gamper F, et al. Ante-rior implant restorations with a convex emergence profile increase the frequency of recession: 12-mon-th results of a randomized controlled clinical trial[J]. J Clin Periodontol, 2022, 49(11): 1145-1157. |
| [38] | González-Martín O, Lee E, Weisgold A, et al. Contour management of implant restorations for optimal emergence profiles: guidelines for immediate and delayed provisional restorations[J]. Int J Periodontics Restorative Dent, 2020, 40(1): 61-70. |
| [39] | Chu SJ. Inverted body-shift concept in macroimplant design to enhance biologic and esthetic outcomes: a clinical report[J]. J Prosthet Dent, 2021, 126(6): 720-726. |
| [40] | Lops D, Romeo E, Mensi M, et al. CAD/CAM abutments in the esthetic zone: a systematic review and meta-analysis of soft tissue stability[J]. J Clin Med, 2023, 12(11): 3847. |
| [41] | Wang LN, Wang TT, Lu YF, et al. Comparing the clinical outcome of peri-implant hard and soft tissue treated with immediate individualized CAD/CAM healing abutments and conventional healing abutments for single-tooth implants in esthetic areas over 12 months: a randomized clinical trial[J]. Int J Oral Maxillofac Implants, 2021, 36(5): 977-984. |
| [42] | BinShabaib MS, Mehmood A, Akram Z, et al. Peri-implant clinical and radiographic status and whole salivary cotinine levels among cigarette and waterpipe smokers and never-smokers[J]. J Oral Sci, 2018, 60(2): 247-252. |
| [43] | Stefanini M, Marzadori M, Tavelli L, et al. Peri-implant papillae reconstruction at an esthetically fai-ling implant[J]. Int J Periodontics Restorative Dent, 2020, 40(2): 213-222. |
| [44] | Urban IA, Mancini L, Wang HL, et al. The ‘iceberg’ connective tissue graft technique for peri-implant papilla augmentation following interproximal bone reconstruction[J]. Int J Periodontics Restora-tive Dent, 2024, 44(5): 510-519. |
| [45] | Yi ZM, Miao XH, Wang L, et al. A customized subepithelial connective tissue graft for interdental papilla reconstruction and soft tissue augmentation[J]. J Esthet Restor Dent, 2022, 34(3): 451-460. |
| [46] | Marques T, Santos NBMD, Sousa M, et al. Mixed-thickness tunnel access (MiTT) through a linear vertical mucosal incision for a minimally invasive approach for root coverage procedures in anterior and posterior sites: technical description and case series with 1-year follow-up[J]. Dent J, 2023, 11(10): 235. |
| [47] | Happe A, Schmidt A, Neugebauer J. Peri-implant soft-tissue esthetic outcome after immediate implant placement in conjunction with xenogeneic acellular dermal matrix or connective tissue graft: a rando-mized controlled clinical study[J]. J Esthet Restor Dent, 2022, 34(1): 215-225. |
| [48] | Panwar M, Kosala M, Malik D, et al. Comparison of acellular dermal matrix allografts and connective tissue autografts in soft-tissue augmentation around immediate implants: a pilot study[J]. Med J Armed Forces India, 2022, 78(): S251-S257. |
| [49] | Urban IA, Barootchi S, Urban IA, et al. Hard- and soft-tissue reconstruction in the anterior maxilla for esthetic implant therapy[J]. Compend Contin Educ Dent, 2023, 44(7): 385-389, 390. |
| [50] | Wessels R, Vervaeke S, Seyssens L, et al. A 5-year cohort study on early implant placement with gui-ded bone regeneration or alveolar ridge preservation with connective tissue graft[J]. Clin Implant Dent Relat Res, 2020, 22(6): 697-705. |
| [51] | Miron RJ, Pikos MA, Estrin NE, et al. Extended platelet-rich fibrin[J]. Periodontol 2000, 2024, 94(1): 114-130. |
| [52] | Sharma K, Roy S, Kumari A, et al. A comparative evaluation of soft and hard tissue changes around dental implants placed with and without platelet-rich fibrin[J]. Cureus, 2023, 15(3): e36908. |
| [53] | Tavelli L, Barootchi S, Rasperini G, et al. Clinical and patient-reported outcomes of tissue engineering strategies for periodontal and peri-implant reconstruction[J]. Periodontol 2000, 2023, 91(1): 217-269. |
| [54] | Latimer JM, Maekawa S, Yao Y, et al. Regenerative medicine technologies to treat dental, oral, and craniofacial defects[J]. Front Bioeng Biotechnol, 2021, 9: 704048. |
| [55] | Ebrahimi R, Khorshidi H, Boroumand R, et al. Eva-luation of the effect of hyaluronic acid injection on the reconstruction of reduced interdental papillae in patients referred to Shiraz school of dentistry[J]. J Dent, 2023, 24(3): 305-311. |
| [56] | Becker W, Gabitov I, Stepanov M, et al. Minimally invasive treatment for papillae deficiencies in the esthetic zone: a pilot study[J]. Clin Implant Dent Relat Res, 2010, 12(1): 1-8. |
| [57] | Bertl K, Gotfredsen K, Jensen SS, et al. Can hya-luronan injections augment deficient papillae at implant-supported crowns in the anterior maxilla? A randomized controlled clinical trial with 6 months follow-up[J]. Clin Oral Implants Res, 2017, 28(9): 1054-1061. |
| [58] | Bertl K, Gotfredsen K, Jensen SS, et al. Adverse reaction after hyaluronan injection for minimally invasive papilla volume augmentation. A report on two cases[J]. Clin Oral Implants Res, 2017, 28(7): 871-876. |
| [59] | McGuire MK, Scheyer ET. A randomized, double-blind, placebo-controlled study to determine the safety and efficacy of cultured and expanded autologous fibroblast injections for the treatment of interdental papillary insufficiency associated with the papilla priming procedure[J]. J Periodontol, 2007, 78(1): 4-17. |
| [60] | Wu DT, Munguia-Lopez JG, Cho YW, et al. Polymeric scaffolds for dental, oral, and craniofacial regenerative medicine[J]. Molecules, 2021, 26(22): 7043. |
| [1] | 班红艳,连小丽,代晓华,邹慧儒. 3~6岁儿童乳牙龋病严重程度影响因素分析[J]. 国际口腔医学杂志, 2026, 53(5): 703-710. |
| [2] | 刘伟,杨广良,杨静,甘守艳,罗丽娟,张鎏,国威,黄咏喻,罗宝. 贵州省惠水地区成人牙齿缺失情况调查及影响因素分析[J]. 国际口腔医学杂志, 2026, 53(2): 216-224. |
| [3] | 王晓萌,邝海,何灏逾,李鸿艺,林洁舲,李飞燕. 唇腭裂语音治疗效果及相关因素研究分析[J]. 国际口腔医学杂志, 2025, 52(5): 627-633. |
| [4] | 任家银,游梦. 基于影像学证据的牙骨质—骨结构不良区域的种植考量[J]. 国际口腔医学杂志, 2025, 52(4): 421-427. |
| [5] | 周婕妤,赵蕾,吴亚菲,李勇,赵寰. 腭侧带蒂结缔组织转瓣移植联合冠修复重建美学区龈乳头1例[J]. 国际口腔医学杂志, 2025, 52(3): 323-332. |
| [6] | 赵美林,赵依琼,黄姣. Ⅲ期C级牙周炎正畸患者上前牙龈乳头缺陷伴牙龈退缩1例[J]. 国际口腔医学杂志, 2025, 52(3): 333-340. |
| [7] | 胡雨欣,吕广超,马骁,曹姗姗,李秋兰,赵克,张新平. 牙科树脂渗透陶瓷复合材料制备的研究进展[J]. 国际口腔医学杂志, 2025, 52(1): 133-140. |
| [8] | 吴媚, 梁妍景, 彭雪沛, 陈卫宏, 郭星铜, 侯黎莉. 口腔癌术后言语功能影响因素分析[J]. 国际口腔医学杂志, 2025, 52(1): 42-49. |
| [9] | 薛晶. 流动树脂注射充填技术的临床应用[J]. 国际口腔医学杂志, 2024, 51(6): 653-661. |
| [10] | 蒋佳珍,蒋晓鸽,陈嵩. 颧牙槽嵴区微种植钉成功率的影响因素[J]. 国际口腔医学杂志, 2024, 51(6): 677-686. |
| [11] | 徐一尘,鲁勇. 腭裂术后瘘修复的研究进展[J]. 国际口腔医学杂志, 2024, 51(5): 624-629. |
| [12] | 廖洪林,方仲瀚,张艳艳,刘飞,沈颉飞. 牙种植术后三叉神经创伤性神经病理性疼痛的诊断与防治[J]. 国际口腔医学杂志, 2023, 50(6): 729-738. |
| [13] | 刘云通,刘畅,高丽钞,罗瑜雪,曹钰彬,华成舸. 术后下牙槽神经功能障碍的研究进展[J]. 国际口腔医学杂志, 2023, 50(4): 479-484. |
| [14] | 吴嘉馨,程兴群,吴红崑. 透明质酸在修复龈乳头退缩中的临床应用进展[J]. 国际口腔医学杂志, 2023, 50(3): 347-352. |
| [15] | 陆倩,夏海斌,王敏. 种植体磨光整形术治疗种植体周围炎的研究进展[J]. 国际口腔医学杂志, 2023, 50(2): 152-158. |
|
||